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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. High-throughput functional analysis and clinical relevance of all possible variants of a gene

    SBC: HELIGENICS, INC.            Topic: NHGRI

    Modern pharmaceuticals have greatly improved the quality of life for many patients suffering a variety of illnesses. Unfortunately, among the 17 most commonly prescribed drugs, only 6 are highly effective for most patients, 5 have a modest effect, and 6 show little clinical effect. Worse still, unwanted illness and death from treatment of patients with the incorrect drug or dosage causes over 275, ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Point-of-care lateral flow immunoassay for diagnosis of pertussis

    SBC: DXDISCOVERY INC            Topic: NIAID

    Pertussis (Whooping cough) is a highly contagious, airborne disease that is rapidly re-emerging as a serious public health threat in the United States. Despite high vaccine coverage, annual reported cases in the U.S. have been increasing recently, with an average of 25,000 per year from 2010-2019. This is a level unseen since the early 1960s. Diagnosis of pertussis is challenging because its early ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: 100

    Abstract Duchenne Muscular Dystrophy (DMD) is a fatal muscle disease with an incidence of 1 in 5000 males. DMD results from mutations in the gene encoding dystrophin, a 427 kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and laminin in the extracellular matrix. The α7β1 integrin is a transmembrane linkage system in skeletal and card ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Applications of AI to ensemble forecasts of compound extreme weather events in support of operational adaptation of electric utilities

    SBC: CLIMATE FORECAST APPLICATIONS NETWORK, LLC            Topic: 91

    We propose a high-impact innovation for weather forecasting that integrates global ensemble weather forecasts with an AI-driven post-processing model of extreme weather indices. This innovation will provide the basis for skillful probabilistic forecasts of compound extreme weather events at extended lead times. Extreme weather/climate events of relevance to electric utilities focused on in Phase I ...

    SBIR Phase I 2023 Department of CommerceNational Oceanic and Atmospheric Administration
  5. Cold Spray Low-Friction Composite Metal-Solid Lubricant Coatings

    SBC: APPLIED TUNGSTENITE CORP            Topic: S4

    nbsp;In Phase II, Applied Tungstenite will further explore the cold spray deposition settings and coating compositions to develop a set of coatings that are ready for providing to our customers.In addition to further refining coatings based on the metals studied in Phase I, Applied Tungstenite will expand the trade space to include other base metals, to produce coatings with optimal materials prop ...

    SBIR Phase II 2021 National Aeronautics and Space Administration
  6. Radiological Emergency Responder Field Team Route Training Simulation Using Gaming Technology and Commonly Used Atmospheric Model Outputs

    SBC: Radiation Emergency Services, LLC            Topic: NIEHS

    Project Summary Attachment In the radiological response community, with the exception of a limited number of large-scale exercises, there is a gap in technology that hinders hands-on survey training. Even when there is an available exercise, the compressed time sequence prevents realistic practice for some players, particularly field survey teams. The goal of this Phase I project is to initiate ef ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  7. A novel agent to manage thrombocytopenic patients with platelet transfusion refractoriness

    SBC: FIBROPLATE INC            Topic: NHLBI

    PROJECT SUMMARY Platelet Transfusion Refractoriness (PTR) or the failure to achieve the desired level of blood platelets after platelet transfusion, hampers the management of bleeding episodes in thrombocytopenic patients. PTR condition is associated with a high risk of severe bleeding complications and reduced survival rate, longer hospital stays and higher hospital costs. Existing management str ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  8. Fibrinogen coated albumin spheres to accelerate bone healing in older adults.

    SBC: FIBROPLATE INC            Topic: NIA

    PROJECT SUMMARY Elderly people are at great risk for bone fracture and they are more likely to suffer complications during fracture healing. An inefficient healing process exposes the elderly to higher rates of delayed healing or nonunions. The slow recovery after geriatric fractures dramatically increases risks of degenerative decline, morbidity, and mortality with a negative socio-economic impac ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  9. Ti, Cu, Al / WS2 Composite Dry Film Lubricant

    SBC: APPLIED TUNGSTENITE CORP            Topic: S4

    This SBIR Phase I will formulate and test a metal/WS2 Composite Dry Film Lubricant.The variables which will affect the result are the carrier gas temperature, the impact velocity on the substrate and the ratio of WS2 to metal.Three different metals are being explored to increase chances of success. Harder, higher melting point metals like Ti64 are more challenging for the Cold Spray technique, but ...

    SBIR Phase I 2020 National Aeronautics and Space Administration
  10. Dissimilar Metal Welding of Refractory Metals

    SBC: GENNEXT MATERIALS & TECHNOLOGIES LLC            Topic: Z10

    The fusion welds of dissimilar refractory metals suffer from many limitations including shrinkage cavities, solidification cracking, embrittlement due to impurities, inferior strength and ductility, increased fabrication cost etc. GenNext Materials and Technologies, LLC proposes to develop dissimilar refractory metal friction welds for fabricating hollow cathodes free from these limitations.nbsp;n ...

    SBIR Phase I 2020 National Aeronautics and Space Administration
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