Award Data

X-ray fluorescence spectroscopy is a widely used and extremely sensitive analytical technique for qualitative and quantitative chemical analysis. Superconducting Transition Edge Sensor (TES) microcalorimeter detectors have now been developed that achieve an energy resolution of 2 eV for 1.5 keV X-rays, which is sufficient to enable the measurement of the small shift of the X-ray line position that ...

DESCRIPTION (provided by applicant): According to the National Institutes of Health, there are more than 80 million people in the US who suffer from a potentially sight-threatening disease. Doctors see seven to eight million new cases of eye disease annually. More than two million Americans age 50 and older have advanced AMD, the stage that can lead to severe vision impairment and 10 million have ...

O-glycosylation is one type of important protein modification and plays crucial roles in many cellular processes. Currently, there is limited commercial source for the glycosyl amino acid building blocks that can be utilized in glycopeptide synthesis. Inthis Phase I project, Life BioScience Inc. (LBSI) proposed to utilize its established glycan technologies and extensive research experience of ...

DESCRIPTION provided by applicant Driving while intoxicated DWI is a major public health hazard In the U S there were deaths in caused by alcohol impaired drivers National Highway Traffic Safety Administration NHTSA a The New Mexico Dept of Transportation DoT reported the total DWI cost to New Mexico in alone was over one billion dollars NM DoT In New ...

X-ray fluorescence spectroscopy is a widely used and extremely sensitive analytical technique for qualitative as well as quantitative chemical analysis. Superconducting Transition Edge Sensor (TES) microcalorimeter detectors have now been developed that achieve an energy resolution of 2 eV (full width at half maximum) for 1.5 keV X-rays, which is sufficient to enable the measurement of the small s ...

DESCRIPTION (provided by applicant): The objective of this Phase II competitive renewal project is to implement a clinical study to collect data to validate EyeStar(tm), a software system as the basis for comprehensive telescreening for all stages of diabetic retinopathy (DR). According to the CDC, approximately 80 million people in the U.S. have some form of eye disease, including 20 million dia ...

DESCRIPTION (provided by applicant): This proposed project is motivated by the fact that comprehensive, broad-scale screening for eye diseases such as age-related macular degeneration (AMD), glaucoma, and diabetic retinopathy (DR), including advanced stages, is economically prohibitive without the introduction of computer-assisted diagnosis of retinal images. According to the CDC approximately 80 ...

DESCRIPTION (provided by applicant): This SBIR project is developing a system capable of remotely monitoring, in real-time, the adherence of an HIV patient to Antiretroviral therapy (ART). ART is a medication regimen that once started, needs to be followedfor the rest of the patient's life. ART has been successful in improving the quality and expectancy of life of HIV patients as well as in r ...

DESCRIPTION (provided by applicant): The annual healthcare costs of heavy drinking in the U.S. are estimated to be 24.6 billion (Bouchery et al., 2011). Effectively intervening with hazardous, risky, and problem drinkers would reduce both their morbidityand their healthcare costs. One way to address the needs of problem drinkers is by screening for and intervening with them in primary care. It is ...

DESCRIPTION (provided by applicant): Preterm infants (lt 37 weeks gestation) have difficulty with oral feeding due to immature suck, swallow, respiration, and low endurance. As the ability to feed by mouth is a criterion for hospital discharge, it is oftendelayed, leading to increased medical cost, maternal stress, and delayed mother-infant reunification. No oral feeding device currently exists to ...