Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. A Synthetic Human Cytomegalovirus Vaccine Platform

    SBC: TOMEGAVAX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The goal of this project is to synthesize, based on genomic sequence information, a human cytomegalovirus (HCMV) strain with demonstrated ability to establish persistent infection in sero-positive individuals. The resulting synthetic product will form the basis for the development of attenuated HCMV vaccines. Innovative synthetic biology methods will overcome ...

    STTR Phase I 2013 Department of Health and Human Services
  2. Quantitative dual-mode scanner for breast cancer therapy

    SBC: PET/X LLC            Topic: NCI

    DESCRIPTION (provided by applicant): The goal of this project is to develop a dual-mode PET/x-ray mammography scanner (PET/X) to improve the way in which breast cancer therapies are matched to patients by providing early evaluation of therapy efficacy through 'window' studies on an individual patient basis. More than 200,000 women in the US start therapy for breast cancer each year. In 2 ...

    STTR Phase I 2013 Department of Health and Human Services
  3. Primary Screener for Mathematics (PSM) and Diagnostic Assessment of Math Skills

    SBC: STRETCHING CHARTS, INC.            Topic: NICHD

    DESCRIPTION (provided by applicant): Based on the poor performance of fourth grade students on national and international tests of mathematics, it is evident students in the early grades are not adequately prepared in mathematics. Several researchers havedemonstrated that students who complete kindergarten with an inadequate knowledge of basic mathematics concepts and skills will continue to exper ...

    STTR Phase I 2013 Department of Health and Human Services
  4. Instrumentation enabling a 16-fold decrease in oligonucleotide cost

    SBC: APDM, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): Although balance and gait disorders are one of the most common and devastating chronic medical problems of older people, especially those with chronic neurological diseases, clinicians or clinical researchers do not measure balance and gait frequently, accurately, or sensitively. Our long-term goal is to develop and commercialize a unique system called the Hom ...

    SBIR Phase I 2013 Department of Health and Human Services
  5. Process Development on a Schistosomiasis Vaccine, SchistoShield???

    SBC: PAI Life Sciences, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Schistosomiasis is a major neglected tropical disease of public health concern to a billion people with 200 million currently infected and 779 million at risk to acquire the infection, the majority of these in Africa.The disease has a high impact on affected people's lives with disability adjusted life years at 70 million years which rank this malady ahea ...

    SBIR Phase I 2013 Department of Health and Human Services
  6. Vaccine Adjuvant for Rapid Tolerance Induction in Allergy Patients

    SBC: TRIA BIOSCIENCE CORP.            Topic: NIAID

    DESCRIPTION (provided by applicant): Allergy is a major cause of illness and disability with an estimated 40-50 million people afflicted in the US alone. AIT provides long-term benefits for the patient and its need for optimization creates a compelling business opportunity. There is a very strong rationale to develop GLA for allergy based on its superior drug profile to MPL, a related TLR4 agonist ...

    SBIR Phase I 2013 Department of Health and Human Services
  7. Broadly protective (universal) virus-like particle (VLP) based influenza vaccine

    SBC: ALGOMEDIX, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): A safe and effective therapeutic for treatment of osteoarthritis (OA) represents a major unmet medical need. OA is the leading cause of disability in the US and pain is a predominant clinical feature. However, chronicuse of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with potentially life-threatening gastrointestinal bleeding and calculations ...

    SBIR Phase I 2013 Department of Health and Human Services
  8. Minimal Residual Disease Monitoring by T-cell Receptor Repertoire Profiling

    SBC: ADAPTIVE BIOTECHNOLOGIES CORPORATION            Topic: NCI

    DESCRIPTION (provided by applicant): Minimal Residual Disease Monitoring by T-cell Receptor Repertoire Profiling T-cell neoplasms are generally more aggressive and have poorer outcomes than comparable B-cell lymphomas. In addition, for many of these patients, prognosis following disease relapse is dismal. Detecting the presence or absence of Minimal Residual Disease (MRD) following treatment is em ...

    SBIR Phase I 2013 Department of Health and Human Services
  9. Phase II of VerOFy: A New Tool to Improve Productivity for Stress Research

    SBC: PRESAGE BIOSCIENCES, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): With few exceptions, extensive characterization of signal pathway alterations in cancer, and advances in our capacity to identify potent modulators of distinct molecular targets, has not translated into breakthrough drugs. In a recent New York Times article (Nov. 14, 2009), Mervyn Turner, Chief Strategy Officer for Merck was quoted: We invest far too long in b ...

    SBIR Phase I 2013 Department of Health and Human Services
  10. Enzyme Replacement Therapy for Sanfilippo A Lysosomal Rare Disease

    SBC: XL Sci Tech Inc            Topic: NCI

    DESCRIPTION (provided by applicant): Current practice in the USA for inoperable esophageal cancer is a palliative treatment using metal stent for end-stage cancer patients. Outside the USA (especially in Far East countries including China and Korea), therehave been reported clinical benefits of attaching sealed sources such as prostate seeds to the outside of an esophageal stent. Although simple a ...

    SBIR Phase I 2013 Department of Health and Human Services
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