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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Biliary Tract-Specific Fluorescence Image-guided Surgery

    SBC: OPTOSURGICAL LLC            Topic: NIBIB

    Abstract The primary liver cancer including intrahepatic bile duct cancer pose significant global burden of illness with increasing incidence and mortality in US and around the world. Surgery remains the most effective form of treatment. However, surgical complication rates for medium to high complexity hepatectomies persist in 30-40% range even in highly skilled hands and at high volume centers. ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  2. A Biocatalytic Route to Nitrile Reduction

    SBC: QUZYME, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The recently identified ykvM gene family encodes an enzyme belonging to a unique family of nitrile oxido-reductases that catalyze the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine, a transformation never before observed in biology. Nitrile containing compounds are ubiquitous in the pharmaceutical, agricultural, and chemical industries, wh ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Accessible Eye Tracking Solution for Assessment of Cognitive Deficits in Alzheimer's Disease

    SBC: SENAPTEC INC            Topic: NIA

    PROJECT SUMMARY Millions of Americans currently suffer from Alzheimer’s disease, and the number is expected to escalate rapidly in the coming years. The disease prevalence has a significant financial and emotional impact on families, caregivers, and the healthcare system as a whole. Although there is currently no cure for Alzheimer’s, early disease detection and diagnosis of the disease can pr ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Accessible Graphical Display for Numberical Data

    SBC: VIEWPLUS TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term goal of this proposed project is a commercial technology permitting mainstream authors easily to create and distribute a wide variety of one and two dimensional data plots that are easily accessible by all people including those who are blind or have other print disabilities. This would extend the ViewPlus IVEO technology to include virtually all ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Accessible Graphical Display for Numerical Data

    SBC: VIEWPLUS TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long range goal of this project is to provide authoring tools permitting graphical information to be exported from popular computer applications in a form that is universally usable by all people, in particular by p eople who are blind or who have other print disabilities. ViewPlus has already created the hardware and software technologies required for all ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  6. A CD8+ T cell Diagnostic to Identify Children with Pulmonary Tuberculosis

    SBC: ViTi, Inc            Topic: NIAID

    DESCRIPTION (provided by applicant): Tuberculosis (TB) disease, which results from infection with Mycobacterium tuberculosis (Mtb), is a leading cause of infectious morbidity and mortality in children lt 5 years old worldwide. In TB endemic regions, in which the vast majority of the world's annual 9 million adult cases of TB disease reside, children lt 5 years old account for 30-40% of the ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. A CD8+ T cell diagnostic to identify children with pulmonary tuberculosis

    SBC: ViTi, Inc            Topic: NIAID

    DESCRIPTION provided by applicant Tuberculosis TB disease which results from infection with Mycobacterium tuberculosis Mtb is a leading cause of infectious morbidity and mortality in children andlt years old worldwide In TB endemic regions in which the vast majority of the worldandapos s annual million adult cases of TB disease reside children andlt years old account for ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. A Certifiable Federated Identity System for Cross-Agency Collaboration

    SBC: GALOIS, INC.            Topic: N/A

    The Department of Homeland Security's charter has a fundamental requirement to collaborate with other government agencies. Secure collaboration on this scale requires strong identity management which can "vouch for" DHS personnel working with other agencies, and makes it possible to provide DHS resources to individuals in other agencies whose work requires it. We propose the development of a reu ...

    SBIR Phase I 2009 Department of Homeland Security
  9. A Cognitive-Behavioral Multimedia Internet Program to Prevent Youth Depression

    SBC: Oregon Center For Applied Science, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Depression is one of the most prevalent mental disorders to afflict adolescents. It seriously impacts role functioning and typically takes a recurrent or chronic course. Because most depressed youth never receive treatment, there is a critical need to develop effective prevention programs that can be easily implemented and widely disseminated. The proposed proj ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  10. A Combined High-Throughput Single-Cell Transcriptomic and Secretomic Assay for Neurodegenerative Disease Biomarker Discovery

    SBC: ISOPLEXIS CORPORATION            Topic: 105

    In this Phase I application IsoPlexis proposes to deliver a novel method for targeted profiling of both the transcriptome and secretome from an array ofsingle central and peripheral immune cellsSpecificallywe will deliver a single cellmRNA and secreted protein capture assay with proven sensitivity for detecting the most important predictive biomarkers for neurodegenerative diseasesThere is growing ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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