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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. ATCOM SHARP Box for Real-Time Turbulence Mitigation

    SBC: EM PHOTONICS INC            Topic: NASAA402

    When imaging over long distances, atmospheric turbulence between the camera and subject degrades the collected data limiting the effective resolution, regardless of the quality of the optic and sensor used. This reduction in image quality can have serious impacts on the ability to carry out missions by reducing situational awareness and preventing target identification. EM Photonics has been worki ...

    SBIR Phase II 2017 Department of DefenseSpecial Operations Command
  2. A Phase a clinical trial of ALK in geographic atrophy

    SBC: ALKEUS PHARMACEUTICALS, INC.            Topic: NEI

    DESCRIPTION provided by applicant The long term goal of this work is to develop an oral drug for the prevention of age related macular degeneration AMD AMD is the leading cause of blindness in the United States with million Americans diagnosed or at risk of irreversibly losing vision and over million people who already have debilitating vision loss Currently there is no FDA approved ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Multimodal Image Analysis Software for Epilepsy

    SBC: Electrical Geodesics, Inc.            Topic: 108

    DESCRIPTION provided by applicant Epilepsy is a debilitating brain disorder and surgery is the key treatment modality for those patients whose seizures cannot be controlled medically Epilepsy surgery is complex requiring multimodal imaging data for planning and execution and image analysis software is essential for this process The overall goal of this application is to develop a robust com ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. A Cytomegalovirus based therapeutic vaccine against oncogenic human papillomaviruses

    SBC: TOMEGAVAX, INC.            Topic: 102

    Abstract High risk human papillomaviruses HPV cause cervical cancer the second most common neoplasm among women globally and a large proportion of oropharyngeal cancers Although prophylactic vaccines to HPV are effective they have no therapeutic effect and thus do not benefit the millions of individuals already infected Thus there is both a medical need and a commercial opportunity for a HP ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Mobility Life Monitoring Mobility in Daily Lives of People with Neurological Disease

    SBC: APDM, INC.            Topic: NIA

    Project Summary Falls are the leading cause of injuries hospital visits nursing home admissions and reduced quality of life for people with neurological disorders Although there is consensus that impaired mobility is the basis for most falls it is very di cult to evaluate these complex abilities outside a laboratory setting Brief clinical examinations do not accurately re ect daily function ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Development and Commercialization of an Innovative Rapid HIV Incidence Assay

    SBC: SEDIA BIOSCIENCES CORPORATION            Topic: NIAID

    DESCRIPTION provided by applicant The objective of this Phase II project is to develop a commercially viable point of care Rapid HIV Incidence Assay the Asant Rapid HIV Recency Assay and establish its suitability for determination of recency of HIV infection in whole blood plasma serum specimens for epidemiological research and surveillance purposes from liquid blood serum or plasm ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Glycosaminoglycans to Treat and Prevent Radiation Induced Oral Mucositis

    SBC: GLYCOMIRA, LLC            Topic: NIDCR

    ABSTRACT Oral mucositis is a devastatingly painful inflammatory disease that frequently develops during cancer therapy and affects half a million people in the US The accompanying pain is so severe that patients often require narcotic pain medicines The clinical manifestations are ulcers in the mouth and gastrointestinal tract which are exacerbated by opportunistic infections Many patients al ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Nanofiltration Membranes for Isolation of Pharmaceutical Compounds II

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 300

    DESCRIPTION provided by applicant In the manufacture of pharmaceutical compounds organic syntheses are often carried out in organic solvents These solvents must then be separated from high value intermediates and active pharmaceutical ingredients APIs in order to produce the final product medications Many intermediate compounds and APIs are thermally labile and thermal separation processes ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Identifying activators of interferon regulatory factors for neuroprotection

    SBC: Neuralexo, LLC            Topic: 106

    Abstract Stroke is a leading cause of morbidity and mortality in the United States However less than of patients are eligible for the current approved interventions of tissue plasminogen activator or thrombectomy We seek to develop new therapeutics to reduce the extent of damage and functional impairment resulting from ischemic injury to the brain an area of significant unmet medical need ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Therapeutic factor XI blockade for sepsis

    SBC: Aronora, Inc            Topic: NHLBI

    DESCRIPTION provided by applicant Sepsis a detrimental systemic inflammatory and procoagulant response to infections remains a leading cause of death despite antibiotics and significant advances in disease management Antithrombotic drugs e g heparins can limit septic disseminated intravascular coagulation DIC however they can produce severe bleeding side effects and may support pathog ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health

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