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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Chemical-based Nitric Oxide Gas-generating Drug Device for the Treatment of Pulmonary Hypertension

    SBC: INOVODEL, INC.            Topic: NHLBI

    SUMMARY Patients with pulmonary hypertension (PH) experience low oxygen saturation, shortness of breath, low quality of life, and a short life span (lt10 years) following diagnosis. These patients frequently present to emergency rooms, and many are admitted to intensive care units (ICUs), straining the health care system. Despite therapy with phosphodiesterase-5 inhibitors, prostacyclin analogs, a ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Affordable, quantitative, point-of-care microchip-electrophoresis for screening and treatment monitoring of sickle cell disease, thalassemias, and anemias

    SBC: HEMEX HEALTH INC            Topic: NHLBI

    PROJECT SUMMARY Anemia is characterized by low blood hemoglobin levels and has a high prevalence, affecting over one-third of the world's population of about 2.5 billion people. More than 7% of the world’s population carry hemoglobin gene mutations that result in hemoglobin variants, one of which is Sickle Cell Disease (SCD). SCD impacts about 100,000 Americans. The trait form of SCD is the Sick ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Using epigenetic science to improve environmental health literacy

    SBC: NZUMBE INC            Topic: R

    Project Summary NIEHS defines environmental health as “the field of science that studies how the environment influences human health and disease”. The environment in this definition includes the natural environment, man-made chemicals and structures that often pollute the natural environment, and our social interactions and lifestyle choices. Because toxic environments are linked directly to h ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. MomNet: Development of a Coach-Training Program for an Empirically Supported, Guided ehealth Intervention for Depressed Mothers

    SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC.            Topic: 104

    Project Summary/Abstract Economically disadvantaged mothers of young children experience disproportionately high rates of depressive symptoms, yet often do not receive treatment due to instrumental and psychological barriers. Remission of maternal depression relates to improvements in both parenting behavior and child functioning, suggesting that treatment of maternal depression has the potential ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. SIBTime: Media-enhanced Technology for Promoting the Behavioral Health and Family Relationships of Typically Developing Young Siblings

    SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC.            Topic: NIMHD

    Project Summary/AbstractIndividuals who have disabilities and health impairments frequently have typically developing (TD) siblings who share high levels of involvement throughout their lifespan. Increasingly, siblings are being recognized by parents, government, and disability service providers as the next generation of caregivers for people with disabilities, yet the risks and stressors they exp ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Development and testing of a digitally assisted risk reduction platform for youth at high risk for suicide

    SBC: KSANA HEALTH INC            Topic: 104

    ABSTRACTDespite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Although promising approaches are available for preventative interventions with youth at-risk for suicide, they demonstrate modest benefit, and recent reviews have concluded that new developments are required that facilitate not only greater effectiveness, but also enh ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Sourcerer IC: A Web-Based Integrative Multi-Modal Workflow for Epilepsy Surgical Planning

    SBC: Brain Electrophysiology Laboratory Company, LLC            Topic: 106

    Abstract The overarching goal of this project is to create software that improves the use of intracranial EEG to qualify patients with medication-resistant epilepsy for neurosurgery. One million people in the US suffer from continual seizures that are not controlled by medication. The current estimate is that half of these could be treated effectively by surgical resection of the epileptic cortica ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Thrombopoietin Targeting in Myeloproliferative Neoplasms

    SBC: ARONORA INC            Topic: NHLBI

    Project Summary/Abstract Treatment of patients with myeloproliferative neoplasms (MPNs) is limited to palliative and cytoreductive agents that mitigate proliferative blood counts and their effects. Small molecule selective tyrosine kinase (JAK1/JAK2) inhibitors were also shown to provide modest patient benefit, including reduced symptomatology and improved quality of life. Despite the available th ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Novel Nano-immunotherapy for Treatment of Non-small Cell Lung Cancer

    SBC: PDX PHARMACEUTICALS, INC.            Topic: 102

    Treatment of non-small cell lung cancer (NSCLC) typically, which requires a combination of many highly toxicdrugs and radiation therapy, is not curative. Immune checkpoint inhibitors (ICIs) targeting PD-L1/PD-1 are causing a paradigm shift in NSCLC treatment, yet the 5-year survival rate remains below 20%.This Fast-Track SBIR application aims to develop a novel nano-immunotherapy (termed ARAC - An ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Amino Acids and Pediatric Hepatic Steatosis

    SBC: THE AMINO COMPANY LLC            Topic: 300

    7. Project Summary/Abstract Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in North America (1). Hepatic steatosis (HS) is the hallmark of NAFLD (2). NAFLD may transition in sub-groups to chronic inflammation (non- alcoholic steatohepatitis, NASH), and ultimately to cirrhosis. HS is prevalent in all stages of NAFLD. 3-10% of all children in the US and 40-70% of obese ch ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
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