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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Chemical-based Nitric Oxide Gas-generating Drug Device for the Treatment of Pulmonary Hypertension
SBC: INOVODEL, INC. Topic: NHLBISUMMARY Patients with pulmonary hypertension (PH) experience low oxygen saturation, shortness of breath, low quality of life, and a short life span (lt10 years) following diagnosis. These patients frequently present to emergency rooms, and many are admitted to intensive care units (ICUs), straining the health care system. Despite therapy with phosphodiesterase-5 inhibitors, prostacyclin analogs, a ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Affordable, quantitative, point-of-care microchip-electrophoresis for screening and treatment monitoring of sickle cell disease, thalassemias, and anemias
SBC: HEMEX HEALTH INC Topic: NHLBIPROJECT SUMMARY Anemia is characterized by low blood hemoglobin levels and has a high prevalence, affecting over one-third of the world's population of about 2.5 billion people. More than 7% of the world’s population carry hemoglobin gene mutations that result in hemoglobin variants, one of which is Sickle Cell Disease (SCD). SCD impacts about 100,000 Americans. The trait form of SCD is the Sick ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Using epigenetic science to improve environmental health literacy
SBC: NZUMBE INC Topic: RProject Summary NIEHS defines environmental health as “the field of science that studies how the environment influences human health and disease”. The environment in this definition includes the natural environment, man-made chemicals and structures that often pollute the natural environment, and our social interactions and lifestyle choices. Because toxic environments are linked directly to h ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Noregen, a regenerative medicine ocular therapeutic
SBC: Retinal Solutions LLC Topic: NEIABSTRACT Ischemic retinopathies, such as diabetic retinopathy and retinal vein occlusion, are the leading cause of blindness in the United States. Common features are leaky vessels, swelling, capillary drop out, aberrant vessel growth and retinal detachment. Current treatments include laser ablation, anti-VEGFs and steroids. All are sub-optimal and only serve to slow disease progression and vision ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
MomNet: Development of a Coach-Training Program for an Empirically Supported, Guided ehealth Intervention for Depressed Mothers
SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC. Topic: 104Project Summary/Abstract Economically disadvantaged mothers of young children experience disproportionately high rates of depressive symptoms, yet often do not receive treatment due to instrumental and psychological barriers. Remission of maternal depression relates to improvements in both parenting behavior and child functioning, suggesting that treatment of maternal depression has the potential ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
New approach for immune modulation against T1D
SBC: EVOQ THERAPEUTICS, INC. Topic: 200PROJECT SUMMARY/ABSTRACT Type 1 diabetes (T1D) is an autoimmune disease that affects 1 in 300 people by the age of 18 in the US. T1D is characterized by acute onset of hyperglycemia resulting from immune-mediated destruction of the insulin- producing β-cells in the pancreas. There is currently no cure for T1D and the disease requires constant management where the current standard of care/manageme ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Development of MRS-2541, a methionyl-tRNA synthetase inhibitor, for Gram positive bacterial infections.
SBC: TSRL, INC. Topic: NIAIDThe objective of this grant is the preclinical development of MRS-2541, a novel antibiotic structure targeting Gram+ bacteria by a new mechanism of action. MRS-2541 inhibits bacterial methionyl- tRNA synthetase required for bacterial protein synthesis, which is very different from its mammalian counterpart. MRS-2541 is the result of an arduous testing cascade of over 500 compounds requiring broad- ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
SIBTime: Media-enhanced Technology for Promoting the Behavioral Health and Family Relationships of Typically Developing Young Siblings
SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC. Topic: NIMHDProject Summary/AbstractIndividuals who have disabilities and health impairments frequently have typically developing (TD) siblings who share high levels of involvement throughout their lifespan. Increasingly, siblings are being recognized by parents, government, and disability service providers as the next generation of caregivers for people with disabilities, yet the risks and stressors they exp ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Development and testing of a digitally assisted risk reduction platform for youth at high risk for suicide
SBC: KSANA HEALTH INC Topic: 104ABSTRACTDespite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Although promising approaches are available for preventative interventions with youth at-risk for suicide, they demonstrate modest benefit, and recent reviews have concluded that new developments are required that facilitate not only greater effectiveness, but also enh ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Sourcerer IC: A Web-Based Integrative Multi-Modal Workflow for Epilepsy Surgical Planning
SBC: Brain Electrophysiology Laboratory Company, LLC Topic: 106Abstract The overarching goal of this project is to create software that improves the use of intracranial EEG to qualify patients with medication-resistant epilepsy for neurosurgery. One million people in the US suffer from continual seizures that are not controlled by medication. The current estimate is that half of these could be treated effectively by surgical resection of the epileptic cortica ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health