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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Silver coatings to combat catheter associated infections

    SBC: ACRYMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Abstract Indwelling catheterization is a leading cause of nosocomial infections that present an enormous drain of health care funding in the US. Clinical infections associated with urinary catheterization have been estimated to add more than $1000 to patient care. Those that occur with central venous catheterization escalate the cost to between $35,000 and $50, ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Retinoids as Novel Treatment of Ischemic Stroke

    SBC: ACRYMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Stroke is the third leading cause of death in the U.S. and a major source of disability. Ischemic stroke, the most common type, is associated with a dramatic increase in calcium influx in brain tissue, an increased production in reactive oxygen species (ROS), cell death and inflammation. Studies by the PI have shown that retinoids block neuronal voltage-gated c ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Transgenic Plant Technology for Producing Therapeutic Recombinant Antibodies

    SBC: Altor BioScience, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): There is an urgent need to develop novel, cost-effective manufacturing processes to produce therapeutic antibodies commercially in order to reduce the high manufacturing expenses as well as to address the potential for limited manufacturing capacity. The long-term objectives of this application are to develop novel manufacturing processes using transgenic plant ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Tissue Factor Antagonists for ALI/ARDS

    SBC: Altor BioScience, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this project is to develop an anti-tissue factor antibody, Sunol-cH36, as a treatment for Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS). The association between coagulation and inflammation has been well established and a central role in the coagulopathy of ALI/ARDS has been attributed to tissue factor (TF). TF binding ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  5. High-throughput Prediction of Compound Tissue Distribution

    SBC: ANALYTICAL BIOLOGICAL SERVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The aim of the proposed research is to develop tools for the prediction of the distribution of drug compounds in the human body. There is currently no experimental high throughput screening (HTS) method for determining compound tissue distribution. A drug compound's propensity to be taken up by different tissues and organs affects whether it will reach its acti ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Open, Flexible Platform for CAM Adherence Monitoring and Mind-Body Investigations

    SBC: AMES TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There are very few proven biological markers to support complementary and alternative medicine (CAM) adherence investigations. Most tools currently available to CAM investigators are oriented to bio-feedback techniques and of little proven efficacy for use in quantitative research investigations. To support their work, CAM investigators need tools and technolog ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Microarrays in Fathead Minnows and Bass

    SBC: EcoArray, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Microarrays are a powerful way to measure the biological impact of contaminants in the environment. Because they are used to test changes in expression of many genes in parallel, they provide data on the mechanisms by which compounds affect health more quickly than methods now in use, which makes them much less expensive than current tests. Today, gene chips (m ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  8. SIMULATIONS FOR DRUG RELATED SCIENCE EDUCATION

    SBC: ARCHIE MD INC.            Topic: N/A

    N/A

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Development Of A Pulsed Light Emitting Diode Dental Photocuring System

    SBC: B & W TEK INC            Topic: N/A

    DESCRIPTION (provided by applicant): LED based curing lights are beginning to replace conventional halogen lamps as the first choice for dental photo-curing applications. The target of this proposal is to develop a new generation LED dental curing light. It will be the first curing light that is optimized according to the kinetic response of the dental composite, which plays a key role in determin ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Biomarker for liver ischemia/reperfusion-induced injury

    SBC: BANYAN BIOMARKERS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Liver injury induced by hepatic ischemia followed by reperfusion is a major pathogenic cause of liver failure during multiple trauma, thermal injury, hemorrhagic and septic shock, and liver transplantation, which contributes significantly to multiple organ failure and mortality. Current enzymatic assays of serum ALT or LDH are either non-specific or not sensiti ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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