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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Dendritic Cell Subset for Enhanced Cancer Vaccine

    SBC: Aastrom Biosciences, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Tumor antigen primed dendritic cells (DCs) are under widespread clinical evaluation for immunotherapy of multiple forms of cancer. Emerging evidence suggests that DCs are fundamental regulators of the immune response

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Bioreactor for Enhanced T-cell Based Therapy of Melanoma

    SBC: Aastrom Biosciences, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Malignant melanoma is a significant and deadly form of cancer worldwide. Emerging evidence has shown that melanoma cells express tumor-associated antigens that are specifically recognized by the immune system. Melanom

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Catheter to thermally classify atherosclerotic plaque

    SBC: ACCUMED SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of this study will be to detect the prevalence and prognostic value of plaque temperature heterogeneity in diabetic patients undergoing stent implantation. The objective is to develop and commercialize a

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Catheter to thermally classify atherosclerotic plaque

    SBC: ACCUMED SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of this study will be to detect the prevalence and prognostic value of plaque temperature heterogeneity in diabetic patients undergoing stent implantation. The objective is to develop and commercialize an intraluminal Thermal Sensing System (TSS) for taking surface temperature measurements of atherosclerotic plaque lesions within the walls of cor ...

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Antimicrobial Treatment in Burn Graft Biomaterials

    SBC: ACRYMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Burn injuries represent the most terrifying and horrific trauma imaginable. This image is conditioned, in part, from the appearance of surviving bum victims that have been horribly scarred and disfigured follow

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  6. SBIR TOPIC 192- BIOREACTOR TO MONITOR CNCR MMP'S

    SBC: ADVANCED SENSOR TECHNOLOGIES, INC.            Topic: N/A

    N/A

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  7. Incorporating Bone Minerals into Orthopaedic Surfaces

    SBC: ADVANCED SURFACES AND PROCESSES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Submerged Electro-Spark Deposition (SESD, US patent pending), developed at Advanced Surfaces And Processes, Inc., is a surface modification technique. Any conductive surface can be modified with regards to surface texture and chemical composition. The objective of the present proposal is to use SESD to incorporate appreciable amounts of bone mineral elements, i ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  8. Small Animal Handling Devices for Multiplatform Imaging

    SBC: ASI INSTRUMENTS, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Small animal imaging initiatives are growing rapidly due to the enormous potential for improved understanding and treatment of human disease through animal imaging. At present, every radiologic modality available for use in humans has been adapted for small animal use. Other modalities have been devised solely for the purpose of in vivo imaging of research anim ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  9. Novel Antifungals by Engineering the AbA NRPS gene

    SBC: AUREOGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There is an immediate need for efficient, novel antifungal drugs. The fungus Aureobasidium pullulans produces a cyclic peptide know as Aureobasidin A (AbA) which is a very potent, fungicidal drug that is currently bar

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Morpholino Antisense Drugs for Hepatitis C Virus

    SBC: Avi Biopharma, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Hepatitis C Virus (HCV) causes a persistent infection in most humans exposed to the virus. HCV infection in time can lead to cirrhosis and hepatocellular carcinoma. Although the annual number of newly infected patients has dropped significantly over the past decade, about 4 million people are currently persistently infected in the USA. There is presently no un ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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