Award Data

DESCRIPTION (provided by applicant): Pressure ulcers are a significant problem in long-term health care. Estimates of prevalence in the long-term and extended care environments cluster around 8 percent and appear stable over the past decade. Yet it has

DESCRIPTION (provided by applicant): Burn injuries represent the most terrifying and horrific trauma imaginable. This image is conditioned, in part, from the appearance of surviving bum victims that have been horribly scarred and disfigured follow

DESCRIPTION (provided by applicant): This project will develop a package of planning products for radiation treatment that will introduce a measure of quality assurance now lacking, provide clinicians the opportunity to raise tumor dose, and expose the tradeoffs among the treatment constraints and objectives. The new approach based on mixed integer programming (MIP) will ensure that the dose distr ...

DESCRIPTION (provided by applicant): Submerged Electro-Spark Deposition (SESD, US patent pending), developed at Advanced Surfaces And Processes, Inc., is a surface modification technique. Any conductive surface can be modified with regards to surface texture and chemical composition. The objective of the present proposal is to use SESD to incorporate appreciable amounts of bone mineral elements, i ...

DESCRIPTION (provided by applicant): Hepatitis C Virus (HCV) causes a persistent infection in most humans exposed to the virus. HCV infection in time can lead to cirrhosis and hepatocellular carcinoma. Although the annual number of newly infected patients has dropped significantly over the past decade, about 4 million people are currently persistently infected in the USA. There is presently no un ...

DESCRIPTION (provided by applicant): This program is focused on the development of a small-molecule tissue factor/factor Vlla (TF/FVIla) inhibitor with unique anti-inflammatory properties as a novel therapeutic agent for the treatment of unstable angina.

DESCRIPTION (provided by applicant): Cancer is the second leading cause of death in the U.S. Despite very active research in the area, the number of deaths related to cancer has not fallen significantly in the past decade. A major problem associated wi

DESCRIPTION (provided by applicant): Particle adhesion to tissue (vascular endothelium) depends critically upon particle/cell property (size, receptors), scale/geometric features of vasculature (diameter, bifurcation etc.) and local hemodynamic factors

DESCRIPTION (provided by applicant): The goal of the proposed study is to design, fabricate and test an optimal thrombectomy catheter for treatment of ischemic stroke. The size/extent of ischemic damage following a stroke may be dramatically reduced (and

Current bioaerosol monitoring strategies rely on inertia-based sampling and suffer from high power consumption and low efficiency limitations. In contrast, our overall objective is to design and demonstrate a novel electrostatic sampler that provides dramatic improvements including low power requirement (90% for 1-10mm), high viability (>80%), scalability for varying threat scenarios, low noise, a ...