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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Synthetic Human Cytomegalovirus Vaccine Platform

    SBC: TOMEGAVAX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The goal of this project is to synthesize, based on genomic sequence information, a human cytomegalovirus (HCMV) strain with demonstrated ability to establish persistent infection in sero-positive individuals. The resulting synthetic product will form the basis for the development of attenuated HCMV vaccines. Innovative synthetic biology methods will overcome ...

    STTR Phase I 2013 Department of Health and Human Services
  2. Position tracking and mobility assessment system for indoor monitoring of elders

    SBC: EMBEDRF LLC            Topic: NIA

    DESCRIPTION (provided by applicant): The goal of this project is to develop and evaluate a position tracking and mobility assessment system that will enable the elderly to live longer and more safely at home or in an assisted living facility. The ability to move is a critical function tat underlies the quality of life for the elderly. Changes in mobility such as speed of walking have been shown to ...

    STTR Phase II 2013 Department of Health and Human Services
  3. Instrumentation enabling a 16-fold decrease in oligonucleotide cost

    SBC: APDM, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): Although balance and gait disorders are one of the most common and devastating chronic medical problems of older people, especially those with chronic neurological diseases, clinicians or clinical researchers do not measure balance and gait frequently, accurately, or sensitively. Our long-term goal is to develop and commercialize a unique system called the Hom ...

    SBIR Phase I 2013 Department of Health and Human Services
  4. A noninvasive optical imaging of retinal amyloid beta deposits in AD patients

    SBC: Oregon Center For Applied Science, Inc            Topic: NIDA

    DESCRIPTION (provided by applicant): Marital discord is a significant risk factor for a range of negative mental and physical health outcomes.1, 2 Individuals in unhappy relationships experience increases in stress, anxiety, functional impairment, and depressive symptoms3 and are at significant risk for substance abuse disorders.4-7 Furthermore, work loss associated with marital problems translate ...

    SBIR Phase I 2013 Department of Health and Human Services
  5. Integrin Targeted Therapy for the Treatment of Ovarian Cancer

    SBC: BIOSPEECH INC            Topic: NIDA

    Summary Sleep disordered breathing (SDB) is believed to be a widespread, under-diagnosed condition associated with detrimental health problems, at a high cost to society. The current gold standard for diagnosis of SDB is a time- consuming, expensive, and obtrusive (requiring many attached wires) sleep study, or polysomnography (PSG). The immediate objective of the proposed research is to develop a ...

    SBIR Phase I 2013 Department of Health and Human Services
  6. Human Monoclonal Antibody To Treat P. aeruginosa Infections in Cystic Fibrosis

    SBC: Advantage Silver Dental Arrest, LLC            Topic: NIDCR

    DESCRIPTION (provided by applicant): Topical fluorides have been the mainstay in the prevention of dental caries for decades. However, topical fluoride alone is not enough to thwart tooth decay in high-risk populations. The purpose of this Phase I application is to determine the technical and scientific feasibility of using a combination povidone-iodine (PVP-I)-5% sodium fluoride (NaF) varnish as ...

    SBIR Phase I 2013 Department of Health and Human Services
  7. High Cell Density Bioartificial Pancreas Enabled by Implantable Oxygen Generator

    SBC: Pacific Diabetes Technologies            Topic: NIDDK

    DESCRIPTION (provided by applicant): Type 1 diabetes often leads to short-term and long-term complications which impair quality of life. Though many research groups are developing versions of an artificial endocrine pancreas (AP) system, current systems require at least one hormone delivery insertion site and at least one glucose sensor site. This complexity limits commercial viability and potenti ...

    SBIR Phase I 2013 Department of Health and Human Services
  8. Development of a forced air add-on attachment for rocket stoves in Kenya capable

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NIEHS

    DESCRIPTION: Enhanced Membrane System for Supplying Quality Drinking Water Contaminants in Drinking Water: While many of the traditional waterborne diseases (cholera, typhoid) are now uncommon in the developed world, the continue to be a major cause of disease in developing countries and waterborne disease kills more people worldwide than all forms of violence. Waterborne disease outbreaks contin ...

    SBIR Phase I 2013 Department of Health and Human Services
  9. Implantable construct for architectural control of re-vascularization of ischemic

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NIEHS

    DESCRIPTION: Summary Enhanced Recovery of Pharmaceutical Solvent driven by EPA Initiative Recent Events: On July 6, 2011 the United States Environmental Protection Agency (EPA) announced plans to establish new safeguards for hazardous secondary materialsrecycling with objectives to promote the economic, environmental, and public health benefits of recycling wastes, with an emphasis on several ind ...

    SBIR Phase I 2013 Department of Health and Human Services
  10. Early Detection of Evaporative Dry Eye Syndrome (EDE)

    SBC: PAIR TECHNOLOGIES, LLC            Topic: NEI

    DESCRIPTION (provided by applicant): Dry eye (DE) affects 25-30 million people in the U.S. alone and is responsible for 3.84 billion in direct annual health care costs. Evaporative dry eye (EDE) results from a lipid deficiency in tears causing the premature evaporation of tears. The problem to be solved is that current methods for accurately diagnosing EDE take time and are expensive. A fast, obj ...

    SBIR Phase I 2013 Department of Health and Human Services

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