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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel SCD1 inhibitors for treatment of cancer

    SBC: MODULATION THERAPEUTICS, INC.            Topic: 102

    DESCRIPTION provided by applicant Metastatic clear cell renal cell carcinoma mccRCC is an incurable cancer with a year survival of less than for which novel therapeutic agents need to be developed urgently It is notoriously resistant to chemotherapy and radiation Although molecularly targeted therapies have led to an improvement in survival the benefit is rather limited due to event ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. High-potency nitro antimicrobials for topical treatment of trichomoniasis

    SBC: DESIGNMEDIX, INC.            Topic: R

    DESCRIPTION provided by applicant Trichomonas vaginalis is the causative agent of the most common non viral sexually transmitted infection with million new cases reported annually in the world and million cases in the U S In addition to infections of the urogenital tract trichomoniasis increases the risk of adverse pregnancy outcomes and HIV transmission and increases the incidence ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Development of DRα1-MOG-35-55 for treatment of DR2 negative MS subjects

    SBC: VIROGENOMICS BIODEVELOPMENT INC            Topic: NIAID

    DESCRIPTION provided by applicant Our laboratory discovered and is developing partial p MHC class II constructs pMHC as a possible immunotherapy for multiple sclerosis MS pMHC containing the extracellular domains of the MS risk factor HLA DR linked covalently to the encephalitogenic peptide of myelin oligodendrocyte glycoprotein pDR MOG can reverse CNS inflammation and ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. A microchip to analyze trafficking leukocytes in Alzheimer’s disease patients

    SBC: ISOPLEXIS CORPORATION            Topic: NIA

    DESCRIPTION provided by applicant Alzheimerandapos s disease AD is one of the most common neurodegenerative diseases that lead to detrimental outcomes such as progressive memory deficit and cognitive impairment Although it is expected that the prevalence of AD will double over the next years currently no widely accepted molecular biomarkers for early detection or non invasive monitoring ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Advancing Human Health by Lowering Barriers to Electrophysiology in Genetic Model Organisms

    SBC: NEMAMETRIX, INC            Topic: 300

    DESCRIPTION provided by applicant The nematode Caenorhabditis elegans is a powerful experimental system that is widely used as a model for a large number of high impact medical conditions from aging and metabolic disorders to neurodegenerative diseases The strength of this microscopic worm as a medical model derives from the extensive genetic homology between nematodes and humans together ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. ESCALA (Escuela y Carrera Latina/Latino School and Career)

    SBC: IRIS MEDIA INC            Topic: NIMHD

    DESCRIPTION provided by applicant The proposed project will develop ESCALA Escuela y Carrera Latina Latino School and Career a mobile web app designed to increase the college and lowest educational attainment in the United States Because educational attainment is a major social determinant of health it is not surprising that Latinos also experience poor health outcomes compared to white ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Leveraging advanced clinical phenotyping to enhance problem lists and support value-based healthcare

    SBC: VMT, INC.            Topic: NLM

    Project Summary As United States healthcare seeks to address inconsistent quality and overwhelming cost data and technology have become central to all suggested approaches With newly available electronic health data and massive growth in processing power the hardest challenges in using clinical data are becoming clear Big data holds the potential to enable personalized patient care population ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. eHealth Intervention for Postpartum Depression in Healthcare Settings

    SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC.            Topic: 104

    DESCRIPTION provided by applicant Approximately of women experience postpartum depression PPD which results in significant suffering for new mothers and their families and has an adverse impact on infant development Fortunately effective treatments for PPD have been developed and validated However there are many barriers that make it difficult for women with PPD to access clinic ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Single-cell multi-protein device for informative cellular function evaluation

    SBC: ISOPLEXIS CORPORATION            Topic: 100

    DESCRIPTION provided by applicant ELISpot including its variant FLUOROSpot remains the mainstay to measure true secretion of single cells and to assess cellular function e g immunity in the pre clinical and clinical settings However because it measures only one or two proteins per single cell and provides minimal biological information it has limited utility for measuring cell biology an ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. The Madrina Network Web Portal

    SBC: MATIELLA, ANA CONSUELO AND ASSOCIATES            Topic: NCI

    Abstract The Madrina NetworkWeb PortalA Healthy WeightHealthy Lifestyle Intervention for Latinas Ana Consuelo MatiellaPIACMA Social Marketing This Fast Track application addressesa serious health disparityi ethe crisis of obesity among Latinasin the United Statesand the dire need of a timely and culturally and linguistically appropriate weight lossinterventionThis innovative research grant is in d ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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