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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Silver coatings to combat catheter associated infections

    SBC: ACRYMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Abstract Indwelling catheterization is a leading cause of nosocomial infections that present an enormous drain of health care funding in the US. Clinical infections associated with urinary catheterization have been estimated to add more than $1000 to patient care. Those that occur with central venous catheterization escalate the cost to between $35,000 and $50, ...

    SBIR Phase I 2006 Department of Health and Human Services
  2. Retinoids as Novel Treatment of Ischemic Stroke

    SBC: ACRYMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Stroke is the third leading cause of death in the U.S. and a major source of disability. Ischemic stroke, the most common type, is associated with a dramatic increase in calcium influx in brain tissue, an increased production in reactive oxygen species (ROS), cell death and inflammation. Studies by the PI have shown that retinoids block neuronal voltage-gated c ...

    STTR Phase I 2006 Department of Health and Human Services
  3. High-throughput Prediction of Compound Tissue Distribution

    SBC: ANALYTICAL BIOLOGICAL SERVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The aim of the proposed research is to develop tools for the prediction of the distribution of drug compounds in the human body. There is currently no experimental high throughput screening (HTS) method for determining compound tissue distribution. A drug compound's propensity to be taken up by different tissues and organs affects whether it will reach its acti ...

    SBIR Phase I 2006 Department of Health and Human Services
  4. Open, Flexible Platform for CAM Adherence Monitoring and Mind-Body Investigations

    SBC: AMES TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There are very few proven biological markers to support complementary and alternative medicine (CAM) adherence investigations. Most tools currently available to CAM investigators are oriented to bio-feedback techniques and of little proven efficacy for use in quantitative research investigations. To support their work, CAM investigators need tools and technolog ...

    SBIR Phase I 2006 Department of Health and Human Services
  5. Development Of A Pulsed Light Emitting Diode Dental Photocuring System

    SBC: B & W Tek Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): LED based curing lights are beginning to replace conventional halogen lamps as the first choice for dental photo-curing applications. The target of this proposal is to develop a new generation LED dental curing light. It will be the first curing light that is optimized according to the kinetic response of the dental composite, which plays a key role in determin ...

    SBIR Phase II 2006 Department of Health and Human Services
  6. Voice Transformation for Dysarthria- Phase I

    SBC: BIOSPEECH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Software will be developed that transforms speech compromised by dysarthria into easier-to-understand and more natural- sounding speech. The software will reside on laptop computers, with microphone input and amplified speaker or line output. Such software and hardware solutions will assist individuals with dysarthria to better communicate by voice, whether fac ...

    STTR Phase I 2006 Department of Health and Human Services
  7. WeBREATHe: Web-Based Respiratory Education About Tobacco and Health

    SBC: InterVision Media            Topic: N/A

    DESCRIPTION (provided by applicant): In the United States, it is estimated that approximately 43 percent of children under the age of five are exposed to Environmental Tobacco Smoke (ETS) either in the home or in public. There is mounting evidence that childhood exposure to ETS can have pervasive and lasting effects on an individual's health throughout the lifespan. The best described effect of ex ...

    STTR Phase I 2006 Department of Health and Human Services
  8. Home Sensor Date Fusion to Support Aging in Place

    SBC: CLEVERSET, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The aging of the U.S. population presents many challenges. The existing paradigm of care will not allocate resources efficiently as the size of the population requiring home care assistance grows. Our objective is to enhance elder independence by providing both better and more timely predictive health-status assessments and direct, real-time, recommendations an ...

    SBIR Phase II 2006 Department of Health and Human Services
  9. Improved Dehydration Process for Pharmaceutical Synthesis

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Most pharmaceutical synthesis involve condensation or dehydration reactions at some point in the process that generates water as a by-product. This water must be removed since (1) water is often not a desirable component of the finished product, (2) water limits conversion to final product, and (3) water generated slows the reaction rate. Many Pharmaceuticals h ...

    SBIR Phase I 2006 Department of Health and Human Services
  10. High Flux Blood Oxygenators

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Historically blood oxygenator technology either for short-term by-pass surgery or recently developed long-term strategies has been mass transfer limited by liquid side mass transfer fluid dynamics. Recent active mixing designs have led to systems which remove liquid side fluid limitations and have oxygen and carbon dioxide transport limited by membrane transpo ...

    STTR Phase I 2006 Department of Health and Human Services

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