Award Data

We propose to develop a universal strategy to encapsulate protein-based therapeutics using our patented non-toxic, non-immunogenic, water soluble, nanometer size capsules. These nanocapsules have a functionalized surface rendering them "unseen" by the normal immunogenic scavenging response of the body. In addition, the nanoencapsulated proteins not only exhibit superior shelf stability, but are ...

We propose that a comparative colorimetric assay be developed that will use a ticket of the same dimensions as the current ANP immunoassay tickets. This will allow the AChE test to be conducted using a similar workflow as the lateral flow immunoassay-based HHAs and be similarly read on the ANP reader to yield an unambiguous result independent of user judgment.

Low-light-level photodetector arrays are proposed for detecting the weak optical emission spectra from the trace atoms in the laser-induced breakdown spectroscopy (LIBS). The proposed semiconductor image intensifier and low-light-level camera utilize the miniaturized and monolithically integrated version of a proven solid-state detector technology, and is expected to be able to detect femto-watts ...

The integration of NIRS measures with EEG could be a significant advance in rapid detection and continuous monitoring of cerebral dysfunction following traumatic brain injury. We have developed a dense array EEG system that can be applied rapidly in the field environment. We have developed a prototype NIRS brain imaging system that can be integrated with the EEG system, in both sparse and dense ar ...

The integration of NIRS measures with EEG could be a significant advance in rapid detection and continuous monitoring of cerebral dysfunction following traumatic brain injury. We have developed a dense sensor array EEG system that can be applied rapidly in a field environment. We have developed a prototype NIRS brain imaging system that can be integrated with the EEG system, in both sparse and d ...

Hood Technology, along with its partner Williams International, propose to develop, test and supply a Non-Intrusive Stress Measurement System (NSMS) designed specifically for small turboshaft engines. This system will address the issues of these small engines at the sensor, acquisition and software levels, providing a non-proprietary, commercial-based NSMS system tailored for this class of powerp ...

This proposal covers the development and prototype testing of a new Smart Water Piping Corrosion and Scale Monitor for use in the main types of water based utility systems including: potable, closed and open cooling water, condensate, feedwater, and, after the project completion, electric cable cooling. The Monitor will have three main components: a new multi-parameter Corrosion and Scale Sensor, ...

The objective of this research is prove the feasibility of automatically migrating radiation effects predicted in TCAD level tools to compact modeling tools. This transition will enable compact models that possess radiation effects to be quickly generated, which can then be used in circuit design activity. This "model-in-a-day" approach is a substantial improvement over the current ad hoc approach ...

Preservation of the perishable food, especially fresh fruits and vegetables (FF&V), is particularly challenging due to substantial amount of refrigeration required to prevent spoilage. In the case of FF&V, the refrigerated air can quickly become contaminated with ethylene gas produced by the fruits and vegetables, which can lead to autocatalytic ripening of FF&V and accelerate spoilage even at id ...

Silicon carbide (SiC)semiconductors offer revolutionary improvements in power electronics due to much lower conduction and switching losses, higher switching frequencies, higher voltage capability, higher operating temperatures and other superior properties relative to standard silicon. Losses in a converter will be decreased by a factor of ten, frequency will be increased by a factor of ten and ...