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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Silver coatings to combat catheter associated infections

    SBC: ACRYMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Abstract Indwelling catheterization is a leading cause of nosocomial infections that present an enormous drain of health care funding in the US. Clinical infections associated with urinary catheterization have been estimated to add more than $1000 to patient care. Those that occur with central venous catheterization escalate the cost to between $35,000 and $50, ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Synthesis and Processing of Sulfonated Block Copolymer Biomaterials

    SBC: AEGIS BIOSCIENCES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Aegis BioSciences has developed a new and versatile class of anionic, nanostructured hydrogel materials with promising applications in wound care, anti-thrombogenic coatings, and drug delivery. These multi-phase block copolymers are derived from inexpensive, commercially available materials which are subsequently sulfonated. Indeed, growing interest in these ma ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. PROTEASE MODULATING WOUND DRESSINGS FOR THE TREATMENT OF VENOUS ULCERS

    SBC: AEGIS BIOSCIENCES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): It is estimated that 2.5 million people in the United States have chronic venous ulcers. In the developed world, at least 0.1% of the adult population is likely to experience venous ulceration at some time. With the overall prevalence, estimated to be between 1.1 and 3.0 incidents per one thousand individuals, occurrence of venous ulcers increases exponentially ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. High-throughput Prediction of Compound Tissue Distribution

    SBC: ANALYTICAL BIOLOGICAL SERVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The aim of the proposed research is to develop tools for the prediction of the distribution of drug compounds in the human body. There is currently no experimental high throughput screening (HTS) method for determining compound tissue distribution. A drug compound's propensity to be taken up by different tissues and organs affects whether it will reach its acti ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Open, Flexible Platform for CAM Adherence Monitoring and Mind-Body Investigations

    SBC: AMES TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There are very few proven biological markers to support complementary and alternative medicine (CAM) adherence investigations. Most tools currently available to CAM investigators are oriented to bio-feedback techniques and of little proven efficacy for use in quantitative research investigations. To support their work, CAM investigators need tools and technolog ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Intelligent Microtome Instrumentation

    SBC: BARLOW SCIENTIFIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Locating fluorescently-tagged cells in whole organisms is important to the development of gene therapy, stem cell therapy delivery methods, and for drug research. This project will develop an intelligent microtome to identify fluorescently labeled cells in whole mice and to collect those cells in thin sections. During Phase I, a small-mammal cryomicrotome with ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. The DBT-SUD In-Session Response to Dysfunctional Behavior for ACT Teams

    SBC: BEHAVIORAL TECH RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Dissemination of evidence-based practices remains a high priority at NIDA. A number of barriers limit accessibility to these effective practices in routine community-based treatment settings. Persons with severe and persistent mental illness (SPMI) commonly experience both substance use disorders (SUD) and borderline personality disorder (BPD), resulting in ser ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Improved Dehydration Process for Pharmaceutical Synthesis

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Most pharmaceutical synthesis involve condensation or dehydration reactions at some point in the process that generates water as a by-product. This water must be removed since (1) water is often not a desirable component of the finished product, (2) water limits conversion to final product, and (3) water generated slows the reaction rate. Many Pharmaceuticals h ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Smoothing Methods to Investigate Non-linear Effect in Correlated Data Studies

    SBC: Data Numerica Institute, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Correlated data are very common in health studies. Such data could come from longitudinal studies, community panel surveys, genetic family studies or spatial studies. Typically, linear mixed-effect models are used for modeling continuous response, and generalized linear mixed models are applied to non-Gaussian data. In addition to such likelihood approaches, qu ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Analytic Methods for Heterogeneous Multilevel Data

    SBC: Data Numerica Institute, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Multilevel data are very common in sociological, behavioral and biomedical researches. The data could come from longitudinal community surveys, genetic family studies or spatial-temporal studies to investigate some health outcomes. Typically, the interest focuses on the impact of some treatment intervention. Such data could be very complex when there are multip ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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