List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Silver coatings to combat catheter associated infections

    SBC: ACRYMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Abstract Indwelling catheterization is a leading cause of nosocomial infections that present an enormous drain of health care funding in the US. Clinical infections associated with urinary catheterization have been estimated to add more than $1000 to patient care. Those that occur with central venous catheterization escalate the cost to between $35,000 and $50, ...

    SBIR Phase I 2006 Department of Health and Human Services
  2. Retinoids as Novel Treatment of Ischemic Stroke

    SBC: ACRYMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Stroke is the third leading cause of death in the U.S. and a major source of disability. Ischemic stroke, the most common type, is associated with a dramatic increase in calcium influx in brain tissue, an increased production in reactive oxygen species (ROS), cell death and inflammation. Studies by the PI have shown that retinoids block neuronal voltage-gated c ...

    STTR Phase I 2006 Department of Health and Human Services
  3. Transdermal GnRH Delivery System to Treat Infertility

    SBC: ADVANCED SENSOR TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ability to conceive and maintain a pregnancy is a desire most couples expect to fulfill in their lifetime. However, infertility affects between eight and fifteen percent of the American population. One of the most common causes of female infertility is anovulation, or the inability to stimulate and release an egg from the ovary. Although there are a number ...

    SBIR Phase I 2006 Department of Health and Human Services
  4. A Novel Needle-Based X-Ray System

    SBC: ADVANCED X-RAY TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of the project is to develop, clinically test and commercialize the novel insertable x-ray device developed by AXT. This portable x-ray needle, is intended for delivery of low energy, high RBE radiation directly to the tumour beds and is considered to be a viable alternative to radioactive sources used in the High Dose Rate Brachytherap ...

    SBIR Phase II 2006 Department of Health and Human Services
  5. High-throughput Prediction of Compound Tissue Distribution

    SBC: ANALYTICAL BIOLOGICAL SERVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The aim of the proposed research is to develop tools for the prediction of the distribution of drug compounds in the human body. There is currently no experimental high throughput screening (HTS) method for determining compound tissue distribution. A drug compound's propensity to be taken up by different tissues and organs affects whether it will reach its acti ...

    SBIR Phase I 2006 Department of Health and Human Services
  6. Open, Flexible Platform for CAM Adherence Monitoring and Mind-Body Investigations

    SBC: AMES TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There are very few proven biological markers to support complementary and alternative medicine (CAM) adherence investigations. Most tools currently available to CAM investigators are oriented to bio-feedback techniques and of little proven efficacy for use in quantitative research investigations. To support their work, CAM investigators need tools and technolog ...

    SBIR Phase I 2006 Department of Health and Human Services
  7. Novel Antifungals by Engineering the AbA NRPS gene

    SBC: AUREOGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There is an immediate need for novel drugs for the treatment of fungal infections, (antibiotics resistant) bacterial infections, and cancer. Cyclic peptides constitute a class of compounds that have made crucial contributions to the treatment of these diseases. Although cyclic peptides can be very efficient drugs, they are complex natural products and as such, ...

    SBIR Phase II 2006 Department of Health and Human Services
  8. Development Of A Pulsed Light Emitting Diode Dental Photocuring System

    SBC: B & W Tek Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): LED based curing lights are beginning to replace conventional halogen lamps as the first choice for dental photo-curing applications. The target of this proposal is to develop a new generation LED dental curing light. It will be the first curing light that is optimized according to the kinetic response of the dental composite, which plays a key role in determin ...

    SBIR Phase II 2006 Department of Health and Human Services
  9. Purification of Oligonucleotides and Nucleoside Triphosphates

    SBC: BERRY AND ASSOCIATES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Solid-phase oligonucleotide (ON) synthesis produces a complex mixture that contains, in addition to the target sequence, a plethora of other ONs and by-products. Purification is necessary to isolate the desired sequence from these other oligonucleotides. "Trityl-on" purification is a standard technique for short ONs (20-40 mers). In this approach, nucleobase de ...

    SBIR Phase II 2006 Department of Health and Human Services
  10. Low-cost custom microarray synthesis

    SBC: BIODISCOVERY LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In this project our goal is to develop and commercialize a very low cost microarray chip fabrication technology to reduce the cost by as much as a factor of ten and enable the use of microarrays by groups who can not afford the current generation of microarrays. Our technology combines the standard acid labile DMT protection group containing nucleophosphoramidi ...

    STTR Phase I 2006 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government