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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Culture and Modeling of Routine and Non-Routine Behavior

    SBC: 21ST CENTURY SYSTEMS, INC.            Topic: SOCOM06014

    Crowd management is an important task for civilian, police, and military groups that can be very difficult on its own, and becomes even more difficult in hostile environments. The difficulty comes from the many levels of granularity that events can happen at. Making such a system automated adds further challenges, due to difficulties with modeling and sensors. Accurate large-scale crowd models are ...

    SBIR Phase I 2006 Department of DefenseSpecial Operations Command
  2. Intelligent Agent Toolset for 4D/RCS Architectures

    SBC: 21ST CENTURY SYSTEMS, INC.            Topic: N/A

    There is an increasing demand for systems with more autonomous operations interacting with other autonomous and human-based systems. What is needed is an architecture bundled with developer tools for the creation of intelligent real-time control systems that marry the talents of modern control theory, software technology, sensory processing, and semantic knowledge representations. It would be a st ...

    SBIR Phase I 2006 Department of CommerceNational Institute of Standards and Technology
  3. Silver coatings to combat catheter associated infections

    SBC: ACRYMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Abstract Indwelling catheterization is a leading cause of nosocomial infections that present an enormous drain of health care funding in the US. Clinical infections associated with urinary catheterization have been estimated to add more than $1000 to patient care. Those that occur with central venous catheterization escalate the cost to between $35,000 and $50, ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Retinoids as Novel Treatment of Ischemic Stroke

    SBC: ACRYMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Stroke is the third leading cause of death in the U.S. and a major source of disability. Ischemic stroke, the most common type, is associated with a dramatic increase in calcium influx in brain tissue, an increased production in reactive oxygen species (ROS), cell death and inflammation. Studies by the PI have shown that retinoids block neuronal voltage-gated c ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Antagonists of A2B Adenosine Receptors for Asthma

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This is a Phase II SBIR proposal to develop a new therapy for the treatment of asthma. The desired outcome will be the identification of a therapeutic candidate to replace theophylline, a non-selective adenosine receptor antagonist that is effective in treating asthma, but limited by side effects, primarily insomnia, mediated by blockade the A1AR in the brain. ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  6. A2A AR Agonists as Adjunct Therapy Against S. aureus Sepsis

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This is a phase I STTR application to study the efficacy of selective adenosine A2A receptor (A2AR) agonists developed in the laboratories of Adenosine Therapeutics (ATL) in models of Gram-positive bacterial sepsis which will be conducted in the University of Virginia (UVA) laboratories of Dr. Michael Scheld, an expert in the field of infectious disease. Sepsis ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. A2a AR Agonists for Rheumatoid Arthritis

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This is the first revision of a phase I STTR proposal to develop new therapies for the treatment of rheumatoid arthritis (RA). It is collaboration between a biotechnology company, Adenosine Therapeutics, LLC (ATL) based in Charlottesville, VA, and the University of Virginia laboratory of Dr. Donald L. Kimpel, a Rheumatologist experienced in the study of RA. Hum ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Safety of A2A Adenosine Agonist for Treatment of Sepsis

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): ATL146e is a synthetic small molecule developed by Adenosine Therapeutics, LLC (ATL) that acts as a selective agonist of the adenosine A2A receptor. ATL146e, sterile solution for intravenous (i.v.) bolus injection, is currently in Phase III of clinical development for use as a coronary vasodilator in pharmacodynamic stress imaging. ATL146e, when administered pa ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Transdermal GnRH Delivery System to Treat Infertility

    SBC: ADVANCED SENSOR TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ability to conceive and maintain a pregnancy is a desire most couples expect to fulfill in their lifetime. However, infertility affects between eight and fifteen percent of the American population. One of the most common causes of female infertility is anovulation, or the inability to stimulate and release an egg from the ovary. Although there are a number ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. A Novel Needle-Based X-Ray System

    SBC: ADVANCED X-RAY TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of the project is to develop, clinically test and commercialize the novel insertable x-ray device developed by AXT. This portable x-ray needle, is intended for delivery of low energy, high RBE radiation directly to the tumour beds and is considered to be a viable alternative to radioactive sources used in the High Dose Rate Brachytherap ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
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