Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A Synthetic Human Cytomegalovirus Vaccine Platform

    SBC: TOMEGAVAX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The goal of this project is to synthesize, based on genomic sequence information, a human cytomegalovirus (HCMV) strain with demonstrated ability to establish persistent infection in sero-positive individuals. The resulting synthetic product will form the basis for the development of attenuated HCMV vaccines. Innovative synthetic biology methods will overcome ...

    STTR Phase I 2013 Department of Health and Human Services
  2. Quantitative dual-mode scanner for breast cancer therapy

    SBC: PET/X LLC            Topic: NCI

    DESCRIPTION (provided by applicant): The goal of this project is to develop a dual-mode PET/x-ray mammography scanner (PET/X) to improve the way in which breast cancer therapies are matched to patients by providing early evaluation of therapy efficacy through 'window' studies on an individual patient basis. More than 200,000 women in the US start therapy for breast cancer each year. In 2 ...

    STTR Phase I 2013 Department of Health and Human Services
  3. Primary Screener for Mathematics (PSM) and Diagnostic Assessment of Math Skills

    SBC: STRETCHING CHARTS, INC.            Topic: NICHD

    DESCRIPTION (provided by applicant): Based on the poor performance of fourth grade students on national and international tests of mathematics, it is evident students in the early grades are not adequately prepared in mathematics. Several researchers havedemonstrated that students who complete kindergarten with an inadequate knowledge of basic mathematics concepts and skills will continue to exper ...

    STTR Phase I 2013 Department of Health and Human Services
  4. Position tracking and mobility assessment system for indoor monitoring of elders

    SBC: EMBEDRF LLC            Topic: NIA

    DESCRIPTION (provided by applicant): The goal of this project is to develop and evaluate a position tracking and mobility assessment system that will enable the elderly to live longer and more safely at home or in an assisted living facility. The ability to move is a critical function tat underlies the quality of life for the elderly. Changes in mobility such as speed of walking have been shown to ...

    STTR Phase II 2013 Department of Health and Human Services
  5. Monodispersed magnetic nanoparticles for improved diagnostic imaging. Phase II: S

    SBC: LODESPIN LABS, LLC            Topic: NIBIB

    DESCRIPTION (provided by applicant): In the proposed phase II NIH STTR funding opportunity (PA-12-089), LodeSpin Labs (LSL) is developing a magnetic nanoparticle tracer for use in Magnetic Particle Imaging (MPI), a disruptive new medical imaging technologycurrently being developed as a safe, effective and quantitative alternative to existing cardiac imaging technologies like CT and MRI. MPI is a p ...

    STTR Phase II 2013 Department of Health and Human Services
  6. Autologous HIV-1 resistant T cells through accelerated CCR5 gene disruption

    SBC: PRECISION GENOME ENGINEERING, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Treating patients infected with Human Immunodeficiency Virus-1 (HIV-1) is a substantial clinical challenge with evolving pharmaceutical drug and dosing options. Treatments should improve the health and quality of life for HIV-infected individuals by reducing viremia and preserving immunological function. Currents therapeutic approaches utilize combination antir ...

    STTR Phase II 2013 Department of Health and Human Services
  7. Instrumentation enabling a 16-fold decrease in oligonucleotide cost

    SBC: APDM, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): Although balance and gait disorders are one of the most common and devastating chronic medical problems of older people, especially those with chronic neurological diseases, clinicians or clinical researchers do not measure balance and gait frequently, accurately, or sensitively. Our long-term goal is to develop and commercialize a unique system called the Hom ...

    SBIR Phase I 2013 Department of Health and Human Services
  8. Process Development on a Schistosomiasis Vaccine, SchistoShield???

    SBC: PAI Life Sciences, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Schistosomiasis is a major neglected tropical disease of public health concern to a billion people with 200 million currently infected and 779 million at risk to acquire the infection, the majority of these in Africa.The disease has a high impact on affected people's lives with disability adjusted life years at 70 million years which rank this malady ahea ...

    SBIR Phase I 2013 Department of Health and Human Services
  9. Vaccine Adjuvant for Rapid Tolerance Induction in Allergy Patients

    SBC: TRIA BIOSCIENCE CORP.            Topic: NIAID

    DESCRIPTION (provided by applicant): Allergy is a major cause of illness and disability with an estimated 40-50 million people afflicted in the US alone. AIT provides long-term benefits for the patient and its need for optimization creates a compelling business opportunity. There is a very strong rationale to develop GLA for allergy based on its superior drug profile to MPL, a related TLR4 agonist ...

    SBIR Phase I 2013 Department of Health and Human Services
  10. Broadly protective (universal) virus-like particle (VLP) based influenza vaccine

    SBC: ALGOMEDIX, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): A safe and effective therapeutic for treatment of osteoarthritis (OA) represents a major unmet medical need. OA is the leading cause of disability in the US and pain is a predominant clinical feature. However, chronicuse of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with potentially life-threatening gastrointestinal bleeding and calculations ...

    SBIR Phase I 2013 Department of Health and Human Services
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