Award Data

Optofluidics will develop Protein Qspec, a new particle analysis QC instrument designed to characterize protein aggregates in biologic drugs. The primary concern for this class of therapeutics is that they can elicit an immune response from patients who develop anti-drug antibodies which can eliminate the therapeutic benefit. The presence of particulate matter, in these therapeutics (e.g. shed gla ...

A robust system level design process will be used to identify the design of transparent tapered resistive (TTR) elements, including the materials, fabrication processes, and lifecycle costs. The transparent tapered resistive film will be designed to provides a tapered resistive layer across the film while remaining transparent in the visual and near-infrared optical bands for use in radio-frequenc ...

Vibrant Corporation and Sandia National Laboratories (SNL) propose to apply Process Compensated Resonance Testing (PCRT) to the DLA's need for an NDI method to detect counterfeit, nonconforming and improperly processed materiel. PCRT collects and analyzes the resonance frequencies of a component to detect structural defects, characterize material, analyze population variation, monitor manufacturin ...

The objective of this proposal is to demonstrate the feasibility of developing flex hoses for hydraulic and other piping system interfaces that can withstand high pressure environments, hydrodynamic, and other forces unique to deep submergence system operating environments. This hose and connecter system coined FlexiHOSE© proposed by MEI-Charlton, Inc. (MEIC) will meet the need of operating under ...

Modern supercontinuum (SC) light sources are generated by non-linear interactions between ultrashort pulse lasers and optical fibers. Output in near-ultraviolet to near-infrared wavelength ranges has been demonstrated. These light sources have high brightness and are spatially coherent. Recently, output to 4.5 µm was achieved using fluoride glass fibers; optical absorption by the fiber prevents l ...

Southwest Sciences proposes development of residential fire sensing systems based on low cost optical imaging sensors combined with newly introduced highly miniaturized, low power CO sensors. Sensor modules will also include temperature sensors. The modules will be part of a low power wireless network. Each module will be about ½ the size of a business card, a few mm thick, and will operate for ...

A key factor of international efforts to identify and suppress the supply of and demand for nuclear materials, and thereby to deter potential traffickers, is the ability to accurately identify contradicted material and ultimately to trace it back to its origin. Alpha particle spectroscopy is widely used in nuclear forensics to assay trace quantities of sensitive nuclear materials, but the limited ...

Voxtel proposes to develop fiber-coupled near-infrared avalanche photodiode (APD) receivers with photon detection efficiency (PDE) and dark count rate (DCR) with more than two orders of magnitude faster maximum count rate (MCR) than Geiger-mode APDs, which are constrained by a fundamental tradeoff between DCR and MCR: if the APD is cooled to reduce DCR, then its dead time must increase to avoid af ...

THE WORK PROPOSED IN THIS EFFORT IS DIRECTED TOWARDS DETERMINING THE CORRELATION BETWEEN OBSERVED AIRBORNE RADIOIODINE CONCENTRATIONS IN THE AUXILIARY AND FUEL HANDLING BUILDINGS AT TMI-2 FOLLOWING THE ACCIDENT IN 1979 WITH DIURNAL TEMPERATURE VARIATIONS. APPROXIMATELY 5000 MEASUREMENTS WERE MADE DURING THE PERIOD APRIL-JULY, 1979 INDESIGNATED AREAS OF THE AUXILIARY/FUEL HANDLING BUILDING AND THE ...

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