Award Data

The objective of the proposed work is to determine whether Dioxide Materials' miniature C02 sensors have the potential to be adapted for autonomous measurement of ocean carbon. The existing sensors have many advantages for measurements of ocean carbon. They are much smaller and less costly than the existing sensors, work with much smaller gas samples, and use much less power. The sensors were d ...

The goal of this project is to develop, implement, and experimentally validate a new Differential Global Navigation Satellite System (DGNSS) capable of providing sub-centimeter positioning accuracy for quasi-static scientific, mapping, and survey applications. The main feature of the proposed DGNSS solution is that it leverages GNSS reference data from existing NOAA's Continuously Operational Ref ...

Millions of heat pumps are used to heat and cool homes and buildings year round. Continuous operation means that components wear out at a greater rate. As a result, maintenance of residential heat pumps is a major cost driver. Current methods focus on reduced use through control settings. Typically, demand has wide swings throughout the day and people are unable to customize controls. Inevitably, ...

Passive microwave sensors aboard satellites provide valuable information regarding weather conditions by measuring atmospheric attenuation over a broad range of frequencies from 0-200 GHz. Additional ground-based sensors are desirable to provide complementary upward looking measurements that can be used to refine existing attenuation models. Operating over such a large bandwidth, however, places ...

DESCRIPTION (provided by applicant): Underage alcohol consumption is a public health concern with numerous negative sequelae, including adoption of other risky behaviors (smoking, other drug use, at-risk sexual behavior, drinking and driving), increased rates of depression or suicidal ideation, poor academic achievement, and behavioral problems (delinquency, violence, crime). Adolescents who drink ...

PROJECT SUMMARY This project aims to fill the urgent need for a safe and engaging intervention that promotes physical activity in a population of patients with chronic diseases (e.g., diabetes, asthma, osteoarthritis, and chronic heart failure). Compelling evidence suggests that physical activity is an effective therapeutic intervention for numerous chronic diseases. However, in spite of the wide ...

Aging, the progressive degeneration of body and mind, is a universal problem marked by a decline in tissue organization and function, and an increase in the likelihood of death. Progress in understanding the cellular and molecular basis of aging is rapidlyaccelerating, following the discovery that several well-known model organisms age in many of the same ways as humans. In addition to their contr ...

DESCRIPTION (provided by applicant): The objective of this project is to develop a commercially viable point of care Rapid HIV-1 Incidence Assay and establish its suitability for determination of recency of HIV-1 infection in whole blood, plasma, serum specimens for epidemiological, research and surveillance purposes. It is further intended to determine the feasibility of the application of the as ...

DESCRIPTION (provided by applicant): AuraSense Therapeutics (AST), along with Northwestern University, is applying a recently developed technology using oligonucleotide-functionalized nanoparticles (called spherical nucleic acids or SNAs) to control protein expression. These easily synthesized nanoparticles can have either DNA or RNA shells, and are less than 50 nm in hydrodynamic diameter. SNA co ...

DESCRIPTION (provided by applicant): The longterm goal of this project is to utilize cytomegalovirus (CMV) vectors carrying oncogenes of high risk human papillomaviruses (HPV) as novel therapeutic vaccines against cervical cancer. Although recently launched prophylactic vaccines protect against HPV infection, these VLP-based vaccines have not demonstrated significant benefit for individuals who a ...