Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. N/A

    SBC: ADVANCED DIGITAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase I 2003 Department of Health and Human Services
  2. Friction-Reducing Bandage to Prevent Skin Breakdown

    SBC: ADVANCED WOUND SYSTEMS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Pressure ulcers affect approximately 1.7 million patients in the U.S. The overall cost to the healthcare industry for treating pressure ulcers in the U.S. is estimated to exceed $7 billion, and it is well established that the cost of preventing a pressure ulcer is significantly less than its treatment. Skin breakdown is frequently seen in individuals with bot ...

    SBIR Phase I 2003 Department of Health and Human Services
  3. Radiation Protection Cancer Therapy with an SOD Mimetic

    SBC: AEOLUS PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Phase I. In the treatment of cancer, radiation therapy has been limited by the tolerance of the surrounding normal tissues, such as lung or mucosa. Until now, there have been no compounds available that protect the normal tissues without reducing the tumor response to radiation therapy. The overall goal of this project is to develop a new approach to radiation ...

    SBIR Phase I 2003 Department of Health and Human Services
  4. Electrochemical bDNA probe-based measurement of HIV load

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The National Institutes of Allergy and Infectious Disease have called for better tools for the detection and diagnosis of emerging and re-emerging infectious diseases. The need is for tests that are practical and affordable for use in resource poor settings, such as local public health departments in underdeveloped countries, disaster situations anywhere, an ...

    SBIR Phase I 2003 Department of Health and Human Services
  5. One-Step Rapid Screening for Childhood Lead Poisoning

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The CDC states that lead poisoning is the number one environmental health problem affecting children in the US because it affects one of every six at-risk children and it is acknowledged to be a source of cognitive and behavioral impairment. Only 25% of the at-risk US children are tested. Atomic absorption instruments do 80% of blood lead tests in the US, but t ...

    SBIR Phase I 2003 Department of Health and Human Services
  6. New Materials for Plague Antigen and Antibody Detection

    SBC: ANALYTICAL BIOLOGICAL SERVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop novel soluble sensing materials that can be used in homogenous fluorescence assays for the detection of Yersinia pestis antigens and antibodies. Y. pestis is the etiological cause of plague and a potential biowarfare agent. The sensing materials are solutions of functionalized liposomes that become fluorescent when they bind selectively t ...

    SBIR Phase I 2003 Department of Health and Human Services
  7. Screening for anti-RSV compounds with indicator cells

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to use an infection-independent cell-based assay to identify compounds that inhibit respiratory syncytial virus (RSV). The basis of this bioassay is expression of a reporter gene from an artificial viral genome present within the cytoplasm of transfected cells. Significant advances have been made in identifying the cis-acting elem ...

    SBIR Phase I 2003 Department of Health and Human Services
  8. Screening for anti-RSV compounds with indicator cells

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to use an infection-independent cell-based assay to identify compounds that inhibit respiratory syncytial virus (RSV). The basis of this bioassay is expression of a reporter gene from an artificial viral genome present within the cytoplasm of transfected cells. Significant advances have been made in identifying the cis-acting elem ...

    SBIR Phase II 2003 Department of Health and Human Services
  9. Construction of a Respiratory Syncytial Virus Replicon

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Respiratory syncytial virus (RSV) is the most important respiratory pathogen in infants, especially those born prematurely. It is also an important cause of disease in the elderly and immunosuppressed. There is no vaccine available to protect against RSV and "at risk" infants are presently treated by passive immunization. An effective small molecule drug that ...

    SBIR Phase I 2003 Department of Health and Human Services
  10. Multiplexed Gene Assays by Microtiter Plate Microarrays

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The drug discovery industry is under increasing pressure to rapidly prioritize compound candidates based on their efficacy and specificity. Although traditional chip based gene expression microarrays can provide significant insights, sample format and throughput considerations preclude more widespread use. Microtiter plate based microarray (MPMA) systems can be ...

    SBIR Phase I 2003 Department of Health and Human Services
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