Award Data

We propose to continue the development and characterization of a polymeric nanoencapsulation technology that can increase the lifetime of a protein therapeutic agent within a biological system. The materials have been demonstrated to exhibit no cytotoxicity and to efficiently deliver antibody against Protective Antigen of bacillus anthracis.

We propose that a comparative colorimetric assay be developed that will use a ticket of the same dimensions as the current ANP immunoassay tickets. This will allow the AChE test to be conducted using a similar workflow as the lateral flow immunoassay-based HHAs and be similarly read on the ANP reader to yield an unambiguous result independent of user judgment.

ANP Technologies proposes to develop a sample concentration system that uses commercial hollow fiber filtration technology with permanent anti-fouling coatings to concentrate biological contaminants in water sources or supplies to a level high enough to be readily detected. The filter technology will allow simple and quick release of the contaminants into a much smaller volume without the use of ...

Low-light-level photodetector arrays are proposed for detecting the weak optical emission spectra from the trace atoms in the laser-induced breakdown spectroscopy (LIBS). The proposed semiconductor image intensifier and low-light-level camera utilize the miniaturized and monolithically integrated version of a proven solid-state detector technology, and is expected to be able to detect femto-watts ...

Software development organizations are faced with developing and verifying required system software capability, functionality, performance, reliability, and safety, while at the same time meeting tight budget and schedule constraints. Due to software complexity, many programs experience mission critical failures and incur schedule delays and cost overruns. The Army and other organizations, there ...

The objective of the proposed research and development work is to create three new types of multiple-pulse, miniature, and autonomous explosive-driven high-power microwave systems. These systems are to be used to construct small to medium caliber munitions (40-mm to 155-mm), to increase the scope of the target set, and to enhance destruction capability as requested by topic A04-221, High Power Mic ...

The proposed effort extends work recently completed (in 2003) at the University of Missouri – Rolla (UMR) and at Texas A&M University (TAMU) under the “Explosive-Driven Power Generation for Directed-Energy Munitions,” Topic 11 of the DoD FY 98 Multidisciplinary Research Program of the University Research Initiative (MURI II). It also leverages the current efforts by Loki in FCG development u ...

The objective of this research is to develop beta versions of tools for automatically migrating radiation effects predicted in TCAD level tools to compact modeling tools. This transition will enable compact models that possess radiation effects to be quickly generated, which can then be used in circuit design activity. This approach is a substantial improvement over the current ad hoc approaches. ...

Preservation of the perishable food, especially fresh fruits and vegetables (FF&V), is particularly challenging due to substantial amount of refrigeration required to prevent spoilage. In the case of FF&V, the refrigerated air can quickly become contaminated with ethylene gas produced by the fruits and vegetables, which can lead to autocatalytic ripening of FF&V and accelerate spoilage even at id ...

The objective of this proposal is to demonstrate the feasibility of producing novel nanoenergetic composites composed of nanoengineered thermites (mainly, copper oxide, iron oxide and Al-nanoparticles) together with other additives. The synthesis of these composites will be achieved by surfactant templating and self-assembly processes. We propose a process that will result in gram quantities of t ...