Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A CD8+ T cell diagnostic to identify children with pulmonary tuberculosis

    SBC: ViTi, Inc            Topic: NIAID

    DESCRIPTION provided by applicant Tuberculosis TB disease which results from infection with Mycobacterium tuberculosis Mtb is a leading cause of infectious morbidity and mortality in children andlt years old worldwide In TB endemic regions in which the vast majority of the worldandapos s annual million adult cases of TB disease reside children andlt years old account for ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Novel Materials and Methods for Separations of Glycopeptides and Glycans

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: NIGMS

    DESCRIPTION provided by applicant Analysis of glycoprotein polypeptide sites of carbohydrate attachment and the structures of the glycans present on these proteins requires the combination of high resolution chromatographic separations and sophisticated mass spectrometry Hydrophilic interaction liquid chromatography HILIC has great use in separations of glycopeptides and released glycans exhibitin ...

    SBIR Phase II 2013 Department of Health and Human Services
  3. Development of a Long Term pH and pCO2 Lagrangian Drifter

    SBC: SUNBURST SENSORS, LLC            Topic: 831C

    Quantifying oceanic CO2 uptake and ocean acidification and understanding their impact on global climate and ocean ecology are key goals of NOAA’s climate change research programs. NOAA’s request for Development of a long-term Lagrangian pH and pCO2 drifter (SBIR Subtopic 8.3.1C) aims to address these goals by developing technology that measures both pCO2 and pH that can be widely deployed in t ...

    SBIR Phase II 2013 Department of CommerceNational Oceanic and Atmospheric Administration
  4. Dynamic Frequency Passive Millimeter-Wave Radiometer Based on Optical Up-Conversion

    SBC: Phase Sensitive Innovations, Inc.            Topic: 941D

    In the proposed effort, we will leverage this extensive experience and capabilities to realize a frequency agile mmW radiometer that can cover the range of DC-110 GHz and can be scaled to DC-200 GHz under Phase II. Ours is a photonic system that multiplies and up-coverts a low-frequency reference signal onto an optical carrier (laser) using EO modulation, then uses the modulation sidebands to inj ...

    SBIR Phase I 2013 Department of CommerceNational Oceanic and Atmospheric Administration
  5. EMG biofeedback with AMES

    SBC: AMES TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-range goal of this project is to restore functional movement to low-functioning stroke patients using a novel therapeutic regimen and robotic device called AMES, an acronym for Assisted Movement with Enhanced Sensation. In AMES-as it is currently used-the patient's affected limb is moved cyclically with the AMES robotic device while the sensation of ...

    SBIR Phase II 2009 Department of Health and Human Services
  6. Computer assisted disfluency counts for stuttered speech

    SBC: BIOSPEECH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Stuttering is a communication disorder characterized by disfluencies that are frequent and disruptive to communication. Clinicians extensively use disfluency counts to decide whether a client should be treated, to assess treatment progress, and to document treatment outcomes. Clinicians often do disfluency counts in real-time as a speaker is talking. However, ...

    STTR Phase I 2009 Department of Health and Human Services
  7. Tools for Automated Assessment of Language

    SBC: BIOSPEECH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Language and communication problems critically characterize a number of neurodevelopmental disorders including Developmental Language Disorders (DLD) and Autism Spectrum Disorders (ASD). It is increasingly recognized that assessment should include spontaneous natural language samples. There are measures, such as the Index of Productive Syntax (IPSyn), which are ...

    STTR Phase I 2009 Department of Health and Human Services
  8. Evaluating BMY-14802 as an anti-dyskinesia treatment in the 6-OHDA rat model of P

    SBC: SKYBRIDGE PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Our objective is to develop new drug treatments for the side effects of levodopa (L-DOPA) that occur in people with Parkinson's Disease. L-DOPA is the gold standard of treatment for Parkinson's, but unfortunately, the majority of people who take L-DOPA eventually develop debilitating side effects, abnormal involuntary movements called dyskinesias, which may aff ...

    SBIR Phase I 2009 Department of Health and Human Services
  9. Developing MRM-based proteomics software

    SBC: SINGLE ORGANISM SOFTWARE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Multiple reaction monitoring (MRM) is a highly selective, high sensitivity mass spectrometry mode for detecting the presence of particular species in a mixture. In the pharmaceutical industry, many small molecule analytes (e.g. drug metabolites, hormones, and pesticides) are routinely measured in high throughput with MRM's great precision. MRM based assays are ...

    SBIR Phase I 2009 Department of Health and Human Services
  10. Contaminate Removal For Laboratory Pharmaceutical Synthesis

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Most organic pharmaceutical chemical syntheses are done in organic solvents. Oxygen and/or water contaminants in organic solvents will destroy many organic reactants and organometallic reagents and catalysts. As such, the removal of oxygen and water are critical to successful organic synthesis. Unfortunately both oxygen and water are ubiquitous and significant ...

    SBIR Phase I 2009 Department of Health and Human Services
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