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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel Materials and Methods for Separations of Glycopeptides and Glycans

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: NIGMS

    DESCRIPTION provided by applicant Analysis of glycoprotein polypeptide sites of carbohydrate attachment and the structures of the glycans present on these proteins requires the combination of high resolution chromatographic separations and sophisticated mass spectrometry Hydrophilic interaction liquid chromatography HILIC has great use in separations of glycopeptides and released glycans exhibitin ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A CD8+ T cell diagnostic to identify children with pulmonary tuberculosis

    SBC: ViTi, Inc            Topic: NIAID

    DESCRIPTION provided by applicant Tuberculosis TB disease which results from infection with Mycobacterium tuberculosis Mtb is a leading cause of infectious morbidity and mortality in children andlt years old worldwide In TB endemic regions in which the vast majority of the worldandapos s annual million adult cases of TB disease reside children andlt years old account for ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Dynamic Frequency Passive Millimeter-Wave Radiometer Based on Optical Up-Conversion

    SBC: PHASE SENSITIVE INNOVATIONS INC            Topic: 941D

    In the proposed effort, we will leverage this extensive experience and capabilities to realize a frequency agile mmW radiometer that can cover the range of DC-110 GHz and can be scaled to DC-200 GHz under Phase II. Ours is a photonic system that multiplies and up-coverts a low-frequency reference signal onto an optical carrier (laser) using EO modulation, then uses the modulation sidebands to inj ...

    SBIR Phase I 2013 Department of CommerceNational Oceanic and Atmospheric Administration
  4. Fabrication of Advanced Waveguide Structures for Efficient Violet and Near-UV Generation

    SBC: ADVR, INC.            Topic: N/A

    This SBIR Phase I effort will establish the feasibility of fabricating advanced waveguide structures in potassium titanyl phosphate (KTP) capable of efficiently generating 25 to 40 mW of frequency converted light in the 395 to 480 nm. The key innovation in this effort is to utilize KTP waveguides in a single-pass frequency doubling device to efficiently produce the desired laser wavelengths and po ...

    SBIR Phase I 2009 Department of CommerceNational Institute of Standards and Technology
  5. High Efficiency Up conversion Single-Photon-Detector for 1550 nm Signal

    SBC: ADVR, INC.            Topic: N/A

    This NIST Phase II SBIR effort will two low noise single photon detectors using MgO doped LiNbO3 (LN) periodically poled waveguides and a 980nm (or similar appropriate wavelength) pump to up convert 1550nm photons to 600nm to allow for detection by photomultiplier tube (PMT). The key innovation is using low noise periodically poled waveguides with a long wavelength (1800nm) pump leading to higher ...

    SBIR Phase II 2009 Department of CommerceNational Institute of Standards and Technology
  6. EMG biofeedback with AMES

    SBC: AMES TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-range goal of this project is to restore functional movement to low-functioning stroke patients using a novel therapeutic regimen and robotic device called AMES, an acronym for Assisted Movement with Enhanced Sensation. In AMES-as it is currently used-the patient's affected limb is moved cyclically with the AMES robotic device while the sensation of ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Computer assisted disfluency counts for stuttered speech

    SBC: BIOSPEECH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Stuttering is a communication disorder characterized by disfluencies that are frequent and disruptive to communication. Clinicians extensively use disfluency counts to decide whether a client should be treated, to assess treatment progress, and to document treatment outcomes. Clinicians often do disfluency counts in real-time as a speaker is talking. However, ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Tools for Automated Assessment of Language

    SBC: BIOSPEECH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Language and communication problems critically characterize a number of neurodevelopmental disorders including Developmental Language Disorders (DLD) and Autism Spectrum Disorders (ASD). It is increasingly recognized that assessment should include spontaneous natural language samples. There are measures, such as the Index of Productive Syntax (IPSyn), which are ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. Evaluating BMY-14802 as an anti-dyskinesia treatment in the 6-OHDA rat model of P

    SBC: SKYBRIDGE PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Our objective is to develop new drug treatments for the side effects of levodopa (L-DOPA) that occur in people with Parkinson's Disease. L-DOPA is the gold standard of treatment for Parkinson's, but unfortunately, the majority of people who take L-DOPA eventually develop debilitating side effects, abnormal involuntary movements called dyskinesias, which may aff ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. Developing MRM-based proteomics software

    SBC: SINGLE ORGANISM SOFTWARE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Multiple reaction monitoring (MRM) is a highly selective, high sensitivity mass spectrometry mode for detecting the presence of particular species in a mixture. In the pharmaceutical industry, many small molecule analytes (e.g. drug metabolites, hormones, and pesticides) are routinely measured in high throughput with MRM's great precision. MRM based assays are ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
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