Award Data

DESCRIPTION (provided by applicant): Recent advances in cellular immunology have revolutionized our understanding of antigen processing and presentation. UBIVAC, LLC, has an exclusive option on technology (patent pending) that exploits these developments that was developed by Dr. Hong-Ming Hu. Further, the founders of UBIVAC (Drs. Hu and Fox) and their collaborators have investigated additional tr ...

DESCRIPTION (provided by applicant): Naturally occurring smallpox has been eradicated but remains a credible threat to the security of the United States due to its potential use as an agent of terror or biowarfare. Given that approximately 25% of the population is contraindicated to receive the vaccine due to direct risk of adverse events or the possibility of placing direct contacts at risk (23), ...

DESCRIPTION provided by applicant Tuberculosis TB disease which results from infection with Mycobacterium tuberculosis Mtb is a leading cause of infectious morbidity and mortality in children andlt years old worldwide In TB endemic regions in which the vast majority of the worldandapos s annual million adult cases of TB disease reside children andlt years old account for ...

DESCRIPTION (provided by applicant): About one third of women smokers stop smoking cigarettes when they become pregnant. Pregnancy therefore represents an important window of opportunity for these women to build upon their cessation success toward the goal of remaining smokefree for life. Unfortunately, the vast majority of these individuals resume smoking within a year postpartum, despite the fac ...

DESCRIPTION (provided by applicant): This project will develop and evaluate a theoretically-based interactive multimedia program for use by parents and their adolescent children (10-14 years of age) to prevent adolescent pregnancy. The program will include behaviorally focused communication skills training and educational content that is designed to support parental values regarding sexual behavio ...

DESCRIPTION (provided by applicant): The Technological Assistance Institute for Intellectual Disability, Inc. proposes to develop a product line of public health and emergency preparedness education programs to meet the needs of people with disabilities, and the institutions and organizations that serve them. The Live Smart Live Safe (LSLS) programs will address material, behavioral, and emotional ...

DESCRIPTION (provided by applicant): Depression is one of the most prevalent mental disorders to afflict adolescents. It seriously impacts role functioning and typically takes a recurrent or chronic course. There is also mounting evidence for familial transmission of depression. Because most depressed youth never receive treatment, there is a critical need to develop easily accessed prevention pro ...

DESCRIPTION (provided by applicant): DesignMedix has developed a novel class of compounds to address the pressing need for an orally available, inexpensive drug to counter the spread of chloroquine-resistant malaria. Preliminary data showed that this novel class of molecules, called reversed chloroquines (RCQs), acts against both chloroquine- resistant and chloroquine-sensitive malaria in vitro. ...

DESCRIPTION (provided by applicant): Asthma is a chronic inflammatory disease of the airway, affecting more than 20 million Americans. Without proper management it can be life-threatening. Children aged 0-17 have the highest prevalence of asthma, impacting an estimated 8.9 million children. Racial disparities exist in asthma prevalence for children; African- American children are (a) the most like ...

DESCRIPTION (provided by applicant): In Phase II we will complete and evaluate a Web-enhanced pre-service training program for prospective foster caregivers. The program, developed by the Institute for Human Services, is a standardized pre-service training curriculum in current use nationally. Face- to-face contact between agencies and parents allows staff to screen and forge relationships with th ...