Award Data

PCP Ammunition Company will deliver a family of Lightweight Advanced Polymer Sub-Sonic Ammunition. We will do this by adapting our current family of calibers by decreasing the internal volume and shape of the case to match the optimal performance requirements of the cartridges. This will result in a sub-sonic ammunition that is lightweight, clean burning (due to the internal volume and dimension ...

PCP Ammunition Company will research the design and development of Lightweight .50 caliber precision ammunition under this SBIR Phase I contract. PCP will concentrate our efforts on several separate criteria in order to improve upon the current .50 caliber round by utilizing PCP"s current lightweight polymer .50 caliber case. First, we will compare the performance of the current round agains ...

In the proposed effort, we will leverage this extensive experience and capabilities to realize a frequency agile mmW radiometer that can cover the range of DC-110 GHz and can be scaled to DC-200 GHz under Phase II. Ours is a photonic system that multiplies and up-coverts a low-frequency reference signal onto an optical carrier (laser) using EO modulation, then uses the modulation sidebands to inj ...

Quantifying oceanic CO2 uptake and ocean acidification and understanding their impact on global climate and ocean ecology are key goals of NOAA’s climate change research programs. NOAA’s request for Development of a long-term Lagrangian pH and pCO2 drifter (SBIR Subtopic 8.3.1C) aims to address these goals by developing technology that measures both pCO2 and pH that can be widely deployed in t ...

DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a progressive and ultimately fatal neurodegenerative disease that affects more than five million people in the USA. Currently there is no cure for AD. Available medicines are aimed only at temporarily reducing symptoms and slowing down the progression of the disease. While many new compounds have been developed to treat AD, they ...

DESCRIPTION (provided by applicant): The goal of this project is to synthesize, based on genomic sequence information, a human cytomegalovirus (HCMV) strain with demonstrated ability to establish persistent infection in sero-positive individuals. The resulting synthetic product will form the basis for the development of attenuated HCMV vaccines. Innovative synthetic biology methods will overcome ...

DESCRIPTION (provided by applicant): While there is no doubt smoking is a direct causative factor underlying the development of lung cancer, not every smoker develops lung cancer. In fact, only 10-15% of smokers develop this disease, indicating that otherfactors make certain individuals more susceptible to cancer. A number of single nucleotide polymorphisms are known to correlate with the developm ...

DESCRIPTION (provided by applicant): According to the American Cancer Society, half of all men and one-third of all women in the United States will develop cancer in their lifetime. While chemotherapy has dramatically improved the survival rate of cancer patients, it comes at the cost of severe toxicities and in some cases poor response rates. In order to address these shortcomings, equal investme ...

DESCRIPTION (provided by applicant): Procedures on pre-implantation embryos are a cornerstone of much biomedical research; however in all cases, the procedures are very difficult and delicate, requiring exceptionally skilled technical experts and expensive equipment. The difficulties associated with these procedures often results in most such work being avoided by most biomedical research groups. ...

DESCRIPTION (provided by applicant): Preeclampsia, a hypertensive disorder of pregnancy, is a leading cause of maternal and neonatal morbidity and mortality around the world, responsible for approximately 76,000 maternal and 500,000 infant deaths per year.As a heterogeneous and poorly understood disorder, its pathogenesis and possible treatments are an area of active research. While the majority o ...