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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Portable Vibrio Cholerae Concentrator for Sensitive Pathogen Detection in Water

    SBC: Omnivis LLC            Topic: None

    This SBIR Phase I project proposes to develop an easy to use, inexpensive, and portable bacterial concentrator to enable more sensitive cholera pathogen (Vibrio cholerae) detection. Cholera affects communities across 41 countries, including Mozambique in 2019 after Cyclone Idai and Yemen in 2017. Current methods used to detect the cholera pathogen in water involves a 3 to 5-day procedure due to th ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Nanomachine Device for Semiconductor Process Control Monitoring

    SBC: Xallent LLC            Topic: None

    Conventional characterization and test methods are increasingly ineffective when applied to structures less than 100 nanometers, causing challenges across R&D, process control and failure analysis. An increasing number of subtle defects become prominent drivers of failure as device size and operating margins decrease, e.g., processing anomalies in thin gate oxides, substrate problems related to do ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  3. Continuous Learning for Additive Manufacturing Processes Through Advanced Data Analytics

    SBC: Senvol LLC            Topic: NA

    Additive manufacturing (AM) is a promising manufacturing technique for end-use parts that can solve challenges for American manufacturers in many industries, e.g. aerospace, defense, automotive, energy, and healthcare. However, despite the potential that AM offers, the rate of AM adoption in industry is very slow. This is because AM suffers from low repeatability and quality consistency issues, wh ...

    SBIR Phase I 2018 Department of CommerceNational Institute of Standards and Technology
  4. Rapid SERS-based Detection of Sepsis and TBI Biomarkers

    SBC: Ionica Sciences, Inc            Topic: DHA17B004

    Traumatic brain injury (TBI) often occurs when a sudden trauma or head injury disrupts the function of the brain. Common causes of TBI include damage caused by explosive devices, falls and vehicle or motorcycle accidents. Sepsis is the result of a massive immune response to bacterial infection that gets into the blood. Sepsis often leads to organ failure or injury, and has always been a significan ...

    STTR Phase I 2018 Department of DefenseDefense Health Program
  5. MARS, a Maintenance Application for Remote Systems

    SBC: ATC-NY, Inc.            Topic: DHA172004

    System maintenance is time consuming, expensive, and can cause extensive downtime if done improperly. To avoid improper system maintenance, extensive training is often required for existing systems, with additional training required for new capabilities before they can be deployed. This training often slows the deployment of new capabilities. To address issues with system maintenance, the ATC-NY t ...

    SBIR Phase I 2018 Department of DefenseDefense Health Program
  6. Optical Device for Sorting Particles by Size

    SBC: En'urga Inc.            Topic: NA

    This Small Business Innovation Research Phase 1 project will evaluate the feasibility of an innovative optical sizer for estimating drop sizes in sprays that have very small drops. The technique is based on the NIST provisional patent (application number 62/358,264). The NIST invention sorts particles by size over the range of 10nm to 10μm. Drop sizing is achieved in these sprays using an intense ...

    SBIR Phase I 2017 Department of CommerceNational Institute of Standards and Technology
  7. Rapid field testing of field water samples for total coliform and E. coli using isothermal amplification and unique micro-sized particles for cell capture and concentration

    SBC: IFYBER, LLC            Topic: DHA17004

    iFyber LLC proposes to develop a coliform assay with differential detection of E. coli that will circumvent the current challenges with detecting these organisms at a level of 1 CFU/mL in less than 16 hours. The proposed assay targets a result in less than 6 hours by making use of novel microsphere reagents for capture and concentration of the target cells, and coupling these reagents with loop-me ...

    SBIR Phase I 2017 Department of DefenseDefense Health Program
  8. Noninvasive Monitor of Vascular Volume Fluid Shifts

    SBC: Critical Link, LLC            Topic: DHA17007

    The PV[O]H device probes capillaries noninvasively with a single color of light and uses the elastically remitted light as one signal and the inelastically (Stokes scattered) light as another signal. The algorithm processes these two signals to provide an extremely sensitive, precise and accurate simultaneous measurement of relative changes in total intravascular blood volume, plasma volume, red c ...

    SBIR Phase I 2017 Department of DefenseDefense Health Program
  9. Injectable Off-the-Shelf Cell-Based Therapy Cartilage Filler

    SBC: EpiBone, Inc.            Topic: DHA17009

    EpiBone proposed to develop off-the-shelf injectable cell-based cartilage filler for treating cartilage defect such as cartilage tear caused by traumatic injury. The product is generated from allogenic adipose derived mesenchymal stem cells characterized for anti-immunogenic property and prepared into a pre-chondrogenic form. Previously, we have demonstrated that the the cells have tendency to und ...

    SBIR Phase I 2017 Department of DefenseDefense Health Program
  10. High Temperature High Resolution in-situ Differential Pressure Sensor

    SBC: Innoveering, LLC            Topic: 90105

    Chemical manufacturers require high accuracy and high sensitivity pressure sensors to efficiently monitor the various manufacturing systems and processes in the chemical plant, to ensure any changes proceed in a safe and reliable manner, adhering to expected standards and practices. In addition, NIST has a need for highly accurate absolute and differential pressure measurements, especially for det ...

    SBIR Phase I 2016 Department of CommerceNational Institute of Standards and Technology

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