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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Portable Vibrio Cholerae Concentrator for Sensitive Pathogen Detection in Water

    SBC: Omnivis LLC            Topic: None

    This SBIR Phase I project proposes to develop an easy to use, inexpensive, and portable bacterial concentrator to enable more sensitive cholera pathogen (Vibrio cholerae) detection. Cholera affects communities across 41 countries, including Mozambique in 2019 after Cyclone Idai and Yemen in 2017. Current methods used to detect the cholera pathogen in water involves a 3 to 5-day procedure due to th ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Nanomachine Device for Semiconductor Process Control Monitoring

    SBC: Xallent LLC            Topic: None

    Conventional characterization and test methods are increasingly ineffective when applied to structures less than 100 nanometers, causing challenges across R&D, process control and failure analysis. An increasing number of subtle defects become prominent drivers of failure as device size and operating margins decrease, e.g., processing anomalies in thin gate oxides, substrate problems related to do ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  3. Continuous Learning for Additive Manufacturing Processes Through Advanced Data Analytics

    SBC: Senvol LLC            Topic: NA

    Additive manufacturing (AM) is a promising manufacturing technique for end-use parts that can solve challenges for American manufacturers in many industries, e.g. aerospace, defense, automotive, energy, and healthcare. However, despite the potential that AM offers, the rate of AM adoption in industry is very slow. This is because AM suffers from low repeatability and quality consistency issues, wh ...

    SBIR Phase I 2018 Department of CommerceNational Institute of Standards and Technology
  4. Optical Device for Sorting Particles by Size

    SBC: En'urga Inc.            Topic: NA

    This Phase II SBIR project will continue the development of an optical sorter that will be used to estimate drop sizes in sprays. The optical sorter will determine the size of drops in the 0.1 to 10 microns range. Drops in this size range are prevalent in the automobile industry, where the fuel injection pressures have increased tremendously over the past two decades. These newer injectors provide ...

    SBIR Phase II 2018 Department of CommerceNational Institute of Standards and Technology
  5. Doppler Wind Temperature Sounder

    SBC: Brandywine Photonics, LLC            Topic: 8212

    TECHNICAL ABSTRACT: We propose developing a new observational capability for measuring upper atmosphere (20-Km to 200-Km+ altitude) wind and temperature dynamics, based on Doppler imaging of Limb concentrations of NO, N2O, and CO2 called the Doppler Wind Temperature Sounder. The principle of operation is that by measuring the Doppler shift of trace gases created by the differential velocity betwee ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  6. Horizon: Validation of an improved method for rapid characterization of protein aggregates in biologic drugs for increased quality and safety

    SBC: OPTOFLUIDICS, INC.            Topic: NA

    Optofluidics and the University of Delaware propose to complete the development of the Horizon technology and carry out validation via a comprehensive multi-site study. The technology is a subvisible particle analyzer pioneered during Phase I. The technology is designed to fill two critical gaps in biopharmaceutical product development: (1) Scientists can count and image particles with current too ...

    SBIR Phase II 2017 Department of CommerceNational Institute of Standards and Technology
  7. High Temperature High Resolution in-situ Differential Pressure Sensor

    SBC: Innoveering, LLC            Topic: NA

    Chemical manufacturers require high accuracy/high sensitivity pressure sensors to efficiently monitor the various manufacturing systems and processes in the chemical plant, to ensure any changes proceed in a safe and reliable manner, adhering to expected standards and practices. NIST also has a need for highly accurate pressure measurements, especially determining the thermo-physical properties of ...

    SBIR Phase II 2017 Department of CommerceNational Institute of Standards and Technology
  8. Optical Device for Sorting Particles by Size

    SBC: En'urga Inc.            Topic: NA

    This Small Business Innovation Research Phase 1 project will evaluate the feasibility of an innovative optical sizer for estimating drop sizes in sprays that have very small drops. The technique is based on the NIST provisional patent (application number 62/358,264). The NIST invention sorts particles by size over the range of 10nm to 10μm. Drop sizing is achieved in these sprays using an intense ...

    SBIR Phase I 2017 Department of CommerceNational Institute of Standards and Technology
  9. Protein Qspec: An Improved Method for Rapid Characterization of Protein Aggregates in Biologic Drugs for Increased Quality and Safety

    SBC: OPTOFLUIDICS, INC.            Topic: 90201

    Optofluidics will develop Protein Qspec, a new particle analysis QC instrument designed to characterize protein aggregates in biologic drugs. The primary concern for this class of therapeutics is that they can elicit an immune response from patients who develop anti-drug antibodies which can eliminate the therapeutic benefit. The presence of particulate matter, in these therapeutics (e.g. shed gla ...

    SBIR Phase I 2016 Department of CommerceNational Institute of Standards and Technology
  10. High Temperature High Resolution in-situ Differential Pressure Sensor

    SBC: Innoveering, LLC            Topic: 90105

    Chemical manufacturers require high accuracy and high sensitivity pressure sensors to efficiently monitor the various manufacturing systems and processes in the chemical plant, to ensure any changes proceed in a safe and reliable manner, adhering to expected standards and practices. In addition, NIST has a need for highly accurate absolute and differential pressure measurements, especially for det ...

    SBIR Phase I 2016 Department of CommerceNational Institute of Standards and Technology

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