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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Novel assay for the detection of water-born algae toxins

    SBC: Attogene Corporation            Topic: 9203

    Ciguatera fish poisoning is an illness suffered by > 50,000 people yearly after consumption of fish containing ciguatoxins (CTXs) or exposure to a harmful algae bloom (HAB). Manufacturing of critical reagents to develop assays to detect ciguatoxin have been elusive due to the constraints in production of viable amounts of the toxin. Thankfully, a significant amount of work has been done to demonst ...

    SBIR Phase I 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  2. Fluorescent Qdot-Antibody or Aptamer Test Strips for Ultrasensitive Algal Toxin Detection

    SBC: NANOHMICS INC            Topic: 9203

    Nanohmics, Inc. proposes to develop the most sensitive antibody and/or DNA aptamer‐quantum dot (Qdot)‐based lateral flow (LF) test strips possible for detection of harmful algal bloom (HAB) toxins in fresh or saltwater and seafood rinsates. Although commercial colloidal gold‐LF test strips for some HABs and anti‐HAB toxin aptamer DNA sequences already exist, Nanohmics’ innovation of inco ...

    SBIR Phase I 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  3. IF Conversion System for High-Bandwidth Multiplexed Sensors Arrays

    SBC: Alphacore, Inc.            Topic: None

    Alphacore will develop an Intermediate Frequency (IF) Conversion System for High-Bandwidth Multiplexed Sensors Arrays for Phase II of NIST's 2018 soliciation for Exploratory Measurement Science Topic 9.04.02.68.The proposing team has already successfully developed and evaluated a prototype board in Phase I.The goal in Phase II is therefore to achieve three primary objectives:1) Optimize the design ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  4. Multimode Chiroptical Spectrometer for Nanoparticle Characterization

    SBC: Applied Nanofluorescence LLC            Topic: None

    This project will develop a new scientific instrument optimized for the advanced characterization of near-infrared fluorescent nanoparticles that can exist as left- or right-handed structures (enantiomers). Single-walled carbon nanotubes (SWCNTs) are the leading current example of such nanomaterials. Applied NanoFluorescence, LLC (ANF) proposes a novel multi-mode chiroptical spectrometer that can ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  5. A Portable Vibrio Cholerae Concentrator for Sensitive Pathogen Detection in Water

    SBC: Omnivis LLC            Topic: None

    This SBIR Phase I project proposes to develop an easy to use, inexpensive, and portable bacterial concentrator to enable more sensitive cholera pathogen (Vibrio cholerae) detection. Cholera affects communities across 41 countries, including Mozambique in 2019 after Cyclone Idai and Yemen in 2017. Current methods used to detect the cholera pathogen in water involves a 3 to 5-day procedure due to th ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  6. Advanced Manufacturing and Material Measurements Software Tool Weave ™ for the Acceleration and Automation of SEM Image Analysis in the Semiconductor Industry

    SBC: Sandbox Semiconductor Incorporated            Topic: None

    In this Phase I SBIR proposal, SandBox Semiconductor™ proposes to develop an Advanced Manufacturing and Material Measurements software tool called Weave ™ for accelerating and automating SEM image analysis for the semiconductor industry. During the development of a new manufacturing process line for a semiconductor device, tens of thousands of scanning electron microscopy (SEM) images are take ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  7. Nanomachine Device for Semiconductor Process Control Monitoring

    SBC: Xallent LLC            Topic: None

    Conventional characterization and test methods are increasingly ineffective when applied to structures less than 100 nanometers, causing challenges across R&D, process control and failure analysis. An increasing number of subtle defects become prominent drivers of failure as device size and operating margins decrease, e.g., processing anomalies in thin gate oxides, substrate problems related to do ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  8. Gap-Free Model-Based Engineering for Manufacturing and Analysis: Digital Thread without Translation

    SBC: Nvariate, Inc.            Topic: None

    Modern Model-Based Enterprise / Engineering (MBE) systems rely on freeform surfaces built as complex combinations of geometric primitives to define engineered objects. Unfortunately, the intersection of freeform surfaces in MBE applications results in highly approximated solutions, degrading models that cost billions annually by US industry to fix. Current technology limits the abilities of users ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  9. Direct Performance Evaluation of Additive Manufacturing Process Plans

    SBC: INTACT SOLUTIONS INC.            Topic: None

    Additive manufacturing is steadily advancing towards fulfilling its promise of customized and on-demand production of functional parts. However, performance of as-manufactured parts can differ significantly from the as-designed parts because the as-manufactured geometry differs from the as-designed geometry and the asmanufactured material properties are not known. Attempts to predict performance o ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  10. IF Conversion System for High-Bandwidth Multiplexed Sensors Arrays

    SBC: Alphacore, Inc.            Topic: NA

    Alphacore will develop an Intermediate Frequency (IF) Conversion System for High-Bandwidth Multiplexed Sensors Arrays for NIST’s 2018 solicitation for Exploratory Measurement Science Topic 9.04.02.68. The proposing team has already successfully developed and evaluated a similar printed-circuit board (PCB)-based system for NIST (ROACH2 BLAST-TNG, refer section 1.2). The goal in Phase I is therefo ...

    SBIR Phase I 2018 Department of CommerceNational Institute of Standards and Technology

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