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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Advanced IM Compliant Dual-Mode Energetic System

    SBC: Systima Technologies, Inc.            Topic: AF173012

    Systima Technologies, Inc. in collaboration with Aerojet Rocketdyne is proposing to develop and demonstrate a dual mode energetic system design that incorporates an advanced energetic formulation, technology for burn-rate control, and features for IM compliance and system performance enhancement (lethality).The Phase I program includes development and refinement of the system design concepts, comp ...

    SBIR Phase I 2018 Department of DefenseAir Force
  2. Hypersonic Data Recovery

    SBC: Systima Technologies, Inc.            Topic: AF151180

    Systima Technologies, Inc. proposes the development of an unmanned hypersonic test vehicle recovery system that will greatly enhance the effectiveness of hypersonic flight testing. Systima plans to perform a comprehensive review of the various hypersonic vehicle test environments and recovery requirements in order to develop recommendations for suitable vehicle recovery technologies for the range ...

    SBIR Phase II 2018 Department of DefenseAir Force
  3. A Blubber- or Dorsal Fin-Piercing Tag Attachment System for Remotely-Deployed Cetacean Tags

    SBC: American Benchmark Machine Works            Topic: 824

    TECHNICAL ABSTRACT: Animal-borne electronic instruments (tags) are critical tools for monitoring the behavior and ecology of cetaceans, providing data needed for managing their populations and mitigating the threats they face. Although remote-deployment of tags onto cetaceans that cannot be captured has provided valuable data, attachment durations have been frustratingly short and variable. Our Ph ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  4. RECAL:A New Tool for Disease Detection and Biomolecular Imaging

    SBC: Photon Biosciences LLC            Topic: 400

    Project SummaryAbstract We envision developing a new ultrasensitive detection platform that combines a recombinant protein with a unique imaging media that results in a luminescent protein that is non bleaching and non blinkingThe excitation and emission wavelengths of this protein can be tuned with the choice of imaging media and span much of the visible and near infrared regions of the electroma ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Real-Time Salivary Testosterone and Extension to Mobile Application and Multiple Biomarker Quantification Capability

    SBC: OASIS DIAGNOSTICS CORPORATION            Topic: NIDA

    Program Director Principal InvestigatorLastFirstMiddleSloweyPaul DAbstract This phase I NIH SBIR proposal seeks support for an interdisciplinary partnership between Oasis Diagnosticsand Iowa State University who collaboratively seek to develop a novel tool that can measure and quantify levels of the sex hormone testosterone in saliva within minutes of collectionVerOFytestosteroneThe FDA has urged ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Development of an alpha-conotoxin RgIA analog as a novel, non-opioid therapeutic for chronic neuropathic pain

    SBC: KINETA, INC.            Topic: NIDA

    PROJECT SUMMARY The objective of this SBIR Phase I application is to select an optimized lead analog ofconotoxin RgIA to develop as a uniquenon opioid therapeutic for chronic neuropathic painRgIAa peptide derived from the predatory marine cone snail Conus regiusis an inhibitor of thenicotinic acetylcholine receptornAChRa novel genetically validated pain targetOur current lead candidateKCPpotently ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Design and Optimization of Clinical Gene Gun for Delivery of Nucleic Acid Vaccines

    SBC: Orlance, Inc.            Topic: NIAID

    Gene gun delivery of DNA vaccinesalso known as particle mediated epidermal delivery or PMEDdelivers DNA vaccines coated ontomicron sized gold particles directly into cells of the epidermisIt achieves pain free deliveryis considerably more efficient than electroporation or other DNA vaccine delivery approachesrequiresfold lower dosesand induces both systemic and mucosal responsesThe gene gun stands ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Novel peptide drug conjugates for the treatment of triple-negative breast cancers: Direct anti-tumor activity and immuno-oncology preclinical studies.

    SBC: ONCOTHERAPY SOLUTIONS LLC            Topic: 102

    ABSTRACT Triple negative breast cancersTNBCsare clinically very aggressive tumors with standard chemotherapy the only therapeutic option for patients with such cancers but the response rates are low and the prognosis remains poorPrevious published studies show that LHRH receptor is detected inof biopsy specimens from patients with TNBC and could be used for delivery of cytotoxic agentsHerewe propo ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Synthetic Universal Flu Vaccine

    SBC: TRIA BIOSCIENCE CORP.            Topic: NCIRD

    Abstract Type A and B Influenza viruses cause severe seasonal epidemics and less frequent but more deadly pandemic infectionsVaccination provides the best protectionalthough serious problems are confronting the global Influenza marketVirus diversity and mutation rates necessitate the annual production of hundreds of millions of vaccines using antiquated egg based technologiesCompounding this is th ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. HLS- A Phase 1 Open-Label Dose-Escalation with Expansion Study of SX-682 in MDS Patients

    SBC: Syntrix Biosystems, Inc.            Topic: NHLBI

    This SBIR Fast Track proposal meets the objectives of NHLBI Small Business Topic of Special Interest for Fiscal YearCode HLSMyelodysplastic syndromesMDSare genetically and morphologically diverse hematopoietic neoplasms that arise from a small pool of mutant clones within hematopoietic stem and progenitor compartmentsOnly three drugs have received regulatory approval specifically for MDS treatment ...

    SBIR Phase I 2018 Department of Health and Human Services

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