Award Data

ABSTRACT: Flow Modeling and Simulation, LLC (FMS), proposes to develop a computational software tool, herein designated AUG3D, that is intended to provide physics-based, multi-level, validated computational simulations of turbine engine component flow fields, particularly those associated with thrust augmentors, i.e., afterburners. This tool will be ideally suited for closely integrating physica ...

ABSTRACT: The SCRAMSIM computer code will be able to perform analysis for engineering design, stemming from a low order Reynolds Average Navier-Stokes (RANS) to high order (4th or higher) LES using accurate subgrid scale models (SGS). It will also solve thermal non-equilibrium mechanisms, conjugated heat transfer, general finite-rate chemistry using several databases for hydrocarbon/hydrogen-air ...

DESCRIPTION (provided by applicant): The natural product artemisinin is a sesquiterpene endoperoxide with known anti-malarial activity against both chloroquine-sensitive and chloroquine-resistant strains of the parasite Plasmodium falciparum. In addition to its anti-malarial activity, artemisinin was reported to have cytotoxic activity against several different tumor cell lines. Recently, artemisi ...

DESCRIPTION (provided by applicant): Invasive candidiasis (IC) is one of the most serious threats to patients in a critical setting. With as many as 60,000 cases per year in the U.S., the total cost associated with IC in the U.S. may be as high as 2-4 billion/year. One of the most critical factors influencing patient outcome is early diagnosis. The goal of this project is a rapi and inexpensive i ...

DESCRIPTION (provided by applicant): Current treatment of solid tumors is limited by normal tissue tolerance, inherent tumor resistance to radiation or chemotherapy, and toxicity from systemic administration of antineoplastic agents. The result is a narrow therapeutic index for most current chemotherapeutic agents. Our long term goal is to overcome these limitations by developing a targeted therap ...

DESCRIPTION (provided by applicant): Poison ivy/oak contact dermatitis is the most prevalent skin allergy in the United States, affecting gt50% of the adult population. The condition is the major cause of occupational hazard among outdoor workers in forestry, agriculture and firefighting, resulting in significant medical expenses and workers disability. Attempts have been made to provide prophyla ...

The Unexploded Ordnance Asset RFID System (UARS) is an active low frequency RFID tracking system designed for locating unexploded ordinance (UXO) on the battlefield.  The system is a passive thin collar RFID tag that is placed onto the munition during manufacture and becomes activated after delivery on target.  Once activated, the RFID tag enters a passive listening mode, waiting for a specific ...

The European Union''s RoHS and WEE Directives mandated the elimination of the carcinogenic, hexavalent chromium coatings for metals, including magnesium and zinc-nickel plated substrates.  The purpose of this project is to find chemistry that will meet requirements of industry performance specifications and of the mandate.  METALAST intends to explore trivalent chromium in conjunction with two o ...

The major requirements for this program include the modeling of optical switching fabric technologies appropriate to space-borne systems at very high speed. Specifically, this program will evaluate two OptiComp candidate optical transceiver technologies against a Serial Rapid IO switching fabric. A down-selection to one optical transceiver technology will be made. Then, a simulation of that Serial ...

The major requirements for this program include the modeling of optical routing technologies appropriate to space-borne systems at very high speed. This program will investigate optical routing at speeds to from 3.125 ro 10 Gbps per channel, with a wavelength/channel density from 4 to 16 wavelengths. Models will be constructed for these regimes, and an experimental demonstration of an 8-wavelength ...