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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Conformable Osteochondral Repair Platforms for Prevention of Post Traumatic Osteoarthritis

    SBC: Theradaptive            Topic: DHA17009

    Our proposal develops an osteochondral repair platform that is conformable to a wide variety of injury geometries without the need for preoperative customization. Further this platform does not rely on any autologous tissue and is amenable to scalable manufacturing methods. The basis of this platform is a targeted delivery technology that permits site-specific osteo-chondral induction within injur ...

    SBIR Phase II 2018 Department of DefenseDefense Health Program
  2. Brain Targeting Nanoparticle for Drug Delivery in Traumatic Brain Injury

    SBC: Weinberg Medical Physics, Inc.            Topic: DHA18A001

    There is an urgent need to bypass or cross the blood brain barrier (BBB) to deliver drugs for TBI treatment. This project aims to develop targted intranasally delivered, magnetically propulsed, and targted nanoparticles for traumatic brain injury (TBI). In Phase I, we will demonstrate the design, fabrication, and in vitro characterization of proposed drug laden magnetic nanoparticles as well as co ...

    STTR Phase I 2018 Department of DefenseDefense Health Program
  3. Medical Electro-Textile Sensor Simulation

    SBC: LR TECHNOLOGIES, Inc.            Topic: DHA17A001

    In this topic, we plan to design a vital EMF sensor to work under any conditions. The sensor will be integrated with smart clothing and using e-textile materials.

    STTR Phase II 2018 Department of DefenseDefense Health Program
  4. Vestibular Rehabilitation Aid (VestAid)

    SBC: Intelligent Automation, Inc.            Topic: DHA172014

    Service members exposed to blasts have frequent complaints of dizziness Appropriate treatment is critical for many reasons: Service members with complaints of dizziness and imbalance are often unable to perform their duties.This results in slower reaction times, decreased productivity (in the form of lost duty days) and negatively impacts force readiness.An integral part of vestibular rehabilitati ...

    SBIR Phase I 2018 Department of DefenseDefense Health Program
  5. Neural Stem Cell Therapy for Severe Traumatic Brain Injury

    SBC: Neuralstem, Inc.            Topic: DHA18004

    We have identified NSI-566, a stable neural stem cell line, isolated and expanded from a single human fetal spinal cord tissue, as the investigational product for TBI treatment.NSI-566 has been approved by the US FDA as an investigational product for clinical testing in ALS (IND# 13905) and chronic SCI (IND# 14413) which are ongoing.For TBI treatment, we propose to place deposits of NSI-566 into t ...

    SBIR Phase I 2018 Department of DefenseDefense Health Program
  6. Delivery System for Cryopreserved Eukaryotic Cell Vaccines

    SBC: SANARIA INC.            Topic: DHP163003

    A cryovial suitable for vaccine storage below -150 C, containing a septum to facilitate syringe preparation in the field does not exist, but is urgently needed for eukaryotic whole cell products. Sanaria PfSPZ Vaccine, consisting of radiation-attenuated whole Plasmodium falciparum sporozoites (PfSPZ), has protected >90% of recipients against malaria in 5 clinical trials in the US, Europe and Afric ...

    SBIR Phase II 2018 Department of DefenseDefense Health Program
  7. SWAC3: Secure Wireless Architecture for Combat Casualty Care

    SBC: Intelligent Automation, Inc.            Topic: A14051

    Current practice for handling pre-hospital documentation is primarily paper based with several major limitations such as ease of loss or destruction, susceptibility to the environment, etc., which along with other factors have been identified as the reasons for the lack of pre-hospital care documentation. Moreover, the information related to care rendered by one unit (e.g., first responders at the ...

    SBIR Phase II 2018 Department of DefenseDefense Health Program
  8. Noninvasive Monitor of Vascular Volume Fluid Shifts

    SBC: INNOVITAL SYSTEMS, INC.            Topic: DHA17007

    Accurate intravascular volume assessment improves the detection of hemorrhage and hypovolemia and facilitates decision-making relative to resuscitation, surgery, and selection of higher level of medical care.Non-invasive assessment techniques are particularly important in the field.Current approaches and devices do not have broad utility and availability.During the Phase I effort, the project team ...

    SBIR Phase II 2018 Department of DefenseDefense Health Program
  9. Virtual Medical Concierge Application

    SBC: Heron Systems, Inc.            Topic: DHP15003

    Enterprises across industry sectors face a common challengehow can they track, analyze and interact with employees, assets and customers based on their movement and physical location Existing solutions, GPS and Wifi, are expensive, battery intensive a

    SBIR Phase II 2018 Department of DefenseDefense Health Program
  10. Delivery System for Cryopreserved Eukaryotic Cell Vaccines

    SBC: SANARIA INC.            Topic: DHP163003

    Sanaria has designed a cryovial for cryopreserving eukaryotic cells that can be used for distribution of cryopreserved eukaryotic cell-based vaccines and is suitable for direct vaccine administration to patients. The cryovials can be stored in liquid nitrogen vapor phase (LNVP) and are currently undergoing testing for suitability as the FDA-registered container for Sanarias Plasmodium falciparum ( ...

    SBIR Phase I 2017 Department of DefenseDefense Health Program

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