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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. NOVEL WOUND DRESSING FOR CHRONIC ULCERS

    SBC: AEGIS BIOSCIENCES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Conservative estimates suggest that over 2 million people annually in the U. S. alone suffer from ulcers, and the base of those so afflicted is likely to increase in view of an aging population. Mean hospital charges of patients with a primary diagnosis for pressure ulcers were about $22,000 in 1992, a significant cost that will become increasingly difficult to ...

    SBIR Phase I 2002 Department of Health and Human Services
  2. ARRAYS TO MEASURE ENDOCRINE DISRUPTION IN FISH

    SBC: EcoArray, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Endocrine disrupting compounds (EDCs) in the environment can cause a variety of physiological problems in animals and humans. Thus, measurement and analysis of EDCs in the environment is very important to the Environmental Protection Agency (EPA) in its Superfund monitoring activities. The investigators have developed a prototype macroarray that works excepti ...

    SBIR Phase I 2002 Department of Health and Human Services
  3. USING AL TO ENHANCE VR ANXIETY DISORDER TREATMENT

    SBC: ARGUS VR INTERNATIONAL            Topic: N/A

    DESCRIPTION (provided by applicant) This project will develop an artificial intelligence to provide the core functionality for virtual reality and computer based treatments for anxiety disorders. The use of artificial intelligence offers a number of advantages over existing treatments: (1) artificial intelligence provides personalized treatment - using multiple real time physiologic and subjective ...

    STTR Phase I 2002 Department of Health and Human Services
  4. GROWTH HORMONE SECRETORY DYNAMICS IN PERIPUBERTAL GIRLS

    SBC: Steven M. Pincus            Topic: N/A

    DESCRIPTION (provided by applicant): The primary objective is to determine the relationship between clinical growth in pubertal girls and boys and shifts in the irregularity of underlying growth hormone (GH) secretory patterns. Novel clarifications of this time-evolution could be significant in determining the proper timing of hormone replacement therapies in pathophysiological settings such as T ...

    SBIR Phase I 2002 Department of Health and Human Services
  5. GRATING-COUPLED EVANESCENT WAVE SENSOR

    SBC: CIENCIA INC            Topic: N/A

    The goal of this effort is to develop a novel label-free detection technology for application to protein microarrays. The objective of the Phase I is to build a breadboard prototype to characterize the performance of this new approach and to establish feasibility. The technology is based on a multilayer grating-coupled (MGR) evanescent wave sensing method with the potential to provide highly mul ...

    SBIR Phase I 2002 Department of Health and Human Services
  6. SYSTEM FOR HIGH THROUGHPUT PROTEOME CHARACTERIZATION

    SBC: CIENCIA INC            Topic: N/A

    N/A

    SBIR Phase I 2002 Department of Health and Human Services
  7. SURFACE PLASMON RESONANCE PROTEIN ARRAY PHENOTYPING

    SBC: CIENCIA INC            Topic: N/A

    A microarray-based system for label-free, high throughput protein expression in profiling in very small volumes of tissue or blood (approximately 10 mL) is proposed. The system will consist of an instrument, and a proteomic biosensor chip integrated into a fluidics cartridge. It utilizes a novel grating-coupled surface plasmon resonance (GC-SPR) imaging technology that will enable measurement of t ...

    SBIR Phase I 2002 Department of Health and Human Services
  8. ADVANCED IMAGING TECHNOLOGY FOR BIOCHIP ANALYSIS

    SBC: CIENCIA INC            Topic: N/A

    DESCRIPTION (provided by applicant)The broad objective of this Fast Track project is to develop and commercialize a versatile and inexpensive CCD-based system for microarray imaging and quantification. A differentiating feature of this system will be the capability to perform time-gated imaging, which will provide the benefits of effective background suppression on certain substrates such as membr ...

    SBIR Phase I 2002 Department of Health and Human Services
  9. PROXIMITRY SURGICAL PROBE

    SBC: Constellation Technology            Topic: N/A

    DESCRIPTION (provided by applicant): An intraoperative surgical probe using a mercuric iodide radiation detector is proposed. The probe will have the ability to simultaneously measure the 140 keV gamma-ray emission and the 18 keV x-ray emission from Tc-99m. Good energy resolution is necessary for the lower energy x-rays to separate them from the potentially large scatter background. Comparison of ...

    SBIR Phase I 2002 Department of Health and Human Services
  10. A NOVEL RF TENS DEVICE FOR ACUTE PAIN MANAGEMENT

    SBC: CYCLOTEC ADVANCED MEDICAL TECHNOLOGIES            Topic: N/A

    DESCRIPTION (provided by applicant): Cyclotec AMT, Inc. is developing 'non-invasive' transcutaneous electrical stimulators (TENS) that may prove to be viable adjuncts to or alternatives for drugs for management of recent onset "acute" pain. TENS has long been used for "chronic" pain management. The device complexities have made them prohibitive for short-term 'acute' applications; an application ...

    STTR Phase I 2002 Department of Health and Human Services

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