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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A BIOMATERIAL FOR ESOPHAGEAL REPAIR

    SBC: ACELL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): ACell is a tissue engineering company and its core technology is based upon a porcine derived extracellular matrix (ECM) harvested from the urinary bladder (UBM) that serves as a constructive scaffold for tissue reconstruction. Successful completion of Phase I studies showed that the UBM-ECM can be configured into a tube shaped device with mechanical and materi ...

    SBIR Phase I 2002 Department of Health and Human Services
  2. A BIOMATERIAL FOR ESOPHAGEAL REPAIR

    SBC: ACELL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): ACell is a tissue engineering company and its core technology is based upon a porcine derived extracellular matrix (ECM) harvested from the urinary bladder (UBM) that serves as a constructive scaffold for tissue reconstruction. Successful completion of Phase I studies showed that the UBM-ECM can be configured into a tube shaped device with mechanical and materi ...

    SBIR Phase II 2002 Department of Health and Human Services
  3. NOVEL CATHETER FOR TREATMENT OF VENTRICULAR TACHYCARDIA

    SBC: Thermedical Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Sudden cardiac death kills 300,000 people in the United States yearly. More than half of these deaths are caused by arrhythmias including ventricular tachycardia. Radiofrequency ablation, which successfully treats supraventricular tachycardia, is not successful at treating ventricular tachycardia because conventional RF ablation catheters cannot treat a large e ...

    SBIR Phase I 2002 Department of Health and Human Services
  4. SECRETED PROTEIN FROM ADIPOCYTES AND PREADIPOCYTES

    SBC: ADIPOGENIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. While weight loss is the most effective treatment of type 2 diabetes, current methods for reducing weight are typically insufficient for long-term weight loss. The mission of AdipoGenix, Inc. is to discover, develop, and license novel therap ...

    SBIR Phase I 2002 Department of Health and Human Services
  5. METAL REPRESSOR TARGETS AND PEPTIDE ACTIVATORS

    SBC: ADVANCED MICROBIAL SOLUTIONS CORPORATION            Topic: N/A

    It is becoming more difficult to treat bacterial infections such as, tuberculosis, staphylococcus, and streptococcus due to the emergence of multiple antibiotic-resistant strains. Rational drug design may prove invaluable for developing new antibiotic agents. Advanced Microbial Solutions Corporation (AMS) developing a new class of anti-microbial agents targeted at metal ion-activated transcription ...

    SBIR Phase I 2002 Department of Health and Human Services
  6. HIGH PERFORMANCE DETECTOR FOR SMALL ANIMAL PET

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant):Positron Emission Tomography (PET) is an in vivo analog of autoradiography, which makes it a potentially powerful new tool for imaging biological processes and molecular targets in small laboratory animals. Its fundamental advantage is that functional data can be obtained non-invasively, allowing each animal to be studied repeatedly. Thus, each animal can serve ...

    SBIR Phase I 2002 Department of Health and Human Services
  7. HIGH PERFORMANCE DETECTOR FOR SMALL ANIMAL PET

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant):Positron Emission Tomography (PET) is an in vivo analog of autoradiography, which makes it a potentially powerful new tool for imaging biological processes and molecular targets in small laboratory animals. Its fundamental advantage is that functional data can be obtained non-invasively, allowing each animal to be studied repeatedly. Thus, each animal can serve ...

    SBIR Phase II 2002 Department of Health and Human Services
  8. HIGH RESOLUTION, LOW COST PET MODULE

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) has become an important tool in the fight against cancer. PET is now being used in diverse studies ranging from basic research in animal models of cancer in the mouse, through to diagnosis and staging of cancer patients in the clinic. It is clear that PET technology is playing a prominent and an increasingly visible role in mo ...

    SBIR Phase I 2002 Department of Health and Human Services
  9. NOVEL DETECTOR FOR SMALL ANIMAL SPECT IMAGING

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    Nuclear medicine techniques (such as SPECT) have the potential to become powerful new tools in imaging biological processes in small laboratory animals. With the every increasing number of human disease models, particularly in the smaller animals such as mice and rats, the potential of high resolution nuclear medicine nuclear medicine technologies to contribute unique information is becoming appar ...

    SBIR Phase I 2002 Department of Health and Human Services
  10. SOLID STATE BETA IMAGING SENSOR FOR IMAGE GUIDED SURGERY

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Nuclear Medicine imaging has been widely used to preoperatively image structures of interest for excisional biopsy. Radio-guided intraoperative procedures utilizing radiotracers have facilitated a cost-effective, highly specific means to locate suspect tissue and access it for pathologic analysis. The result of radio-guided surgery is increased tissue specifici ...

    SBIR Phase I 2002 Department of Health and Human Services

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