Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. HEART RATE VARIABILITY ANALYSIS USING POLYNOMIAL NETWORK

    SBC: ABTECH CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 1996 Department of Health and Human Services
  2. Pediatric Acceptable Formulation of Amiodarone

    SBC: ACADEMIC PHARMACEUTICALS INC            Topic: N/A

    DESCRIPTION (provided by applicant): IV amiodarone is the first line therapy for life threatening ventricular as well as supraventricular arrhythmias. However, the Tween 80 and benzyl alcohol diluents limits the rate of administration severely, due to hypotension and myocardial contractile depression. These adverse toxicities contribute to the high mortality of cardiac arrest patients who have ma ...

    SBIR Phase I 2009 Department of Health and Human Services
  3. LONG RANGE POPULATION PROJECTION BY DISABILITY STATUS

    SBC: Actuarial Research Corporation            Topic: N/A

    N/A

    SBIR Phase I 1996 Department of Health and Human Services
  4. LONG-TERM CARE INSURANCE: A MANUAL FOR REGULATORS

    SBC: Actuarial Research Corporation            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
  5. In vivo Testing of S. aureus alpha-Hemolysin Inhibitors

    SBC: Innovative Biologics Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): We have recently demonstrated that alpha-hemolysin produced by S. aureus plays a key role in the pathogenesis of staphylococcal pneumonia, and identified beta-cyclodextrin derivatives that potently inhibit the cytotoxic effects of this secreted bacterial toxin. The overall goal of this feasibility study is to examine the ability of these inhibitors to provide i ...

    SBIR Phase I 2009 Department of Health and Human Services
  6. Small Molecule Blockers of B. anthracis Toxin

    SBC: Innovative Biologics Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The results from our SBIR Phase II project demonstrated that ?-cyclodextrin derivatives designed to block the transmembrane channel formed by B. anthracis protective antigen can inhibit the cytotoxic effects of anthrax toxin at low- and sub-micromolar concentrations. Several compounds were tested in vivo and showed effective protection in rats challenged with l ...

    SBIR Phase II 2009 Department of Health and Human Services
  7. Controlled Release Vascular Grafts

    SBC: VesselTek Biomedical LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In the United States, it is estimated that 8 million people suffer from peripheral artery disease (PAD). PAD is characterized by a gradual reduction in blood flow to the muscular arteries of the lower extremities caused by atherosclerosis. For those with severe PAD, lower extremity bypass grafting remains the predominant option for limb salvage. Although native ...

    SBIR Phase I 2009 Department of Health and Human Services
  8. Non-Intrusive Automated Portable Data Collection System for Aging Surveys

    SBC: AFrame Digital, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The Cells and Surveys report (National Research Council 2000) reports that collecting biological information dramatically improves the value of household surveys by adding a rich dataset of information to longitudinal databases that is not collected today. In fact, since the Cells and Surveys report the collection of biological data and performance measures (in ...

    SBIR Phase I 2009 Department of Health and Human Services
  9. Interactive Multimedia to Teach Asthma Self Management

    SBC: American Research Corporation of Virginia            Topic: N/A

    We will investigate and develop an interactive multimedia for asthma self-management educationtargeted toward children aged 6-9 inclusive. Interactive multimedia is the integration of audiovisualtechnology (as well as text and graphics) with computer-simulated human interaction to control activitiesand to monitor user responses to computer-generated questions. Interactive multimedia is theeducatio ...

    SBIR Phase II 1996 Department of Health and Human Services
  10. PORTABLE MULTIMEDIA FOR FAMILY CAREGIVER TRAINING

    SBC: American Research Corporation of Virginia            Topic: N/A

    N/A

    SBIR Phase I 1996 Department of Health and Human Services
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