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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Prediction Model for Incident Stroke for Early Screening of an Individual at Risk of Stroke

    SBC: iHealthScreen Inc.            Topic: 105

    ABSTRACT Stroke is one of the leading causes of death and disability in the United States and other developed countriesAboutpeople in the United States have a stroke each yearThe incidence of stroke is expected to increasedue to diabetesan aging population and a rise in obesitywhich is a major public health concern and great economic burden to societyEarly identification of people at risk of strok ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Novel Recombinant High Affinity Long and Dual Acting Equine CG Analogs for Improved and More Ethical Reproduction in Pigs and Cattle

    SBC: TROPHOGEN INC            Topic: NICHD

    As their first application for veterinary health the two PI s have already remarkably employed their novel patented superagonist and neoglycosylation technology to develop the first recombinant much more potent and long acting bovine FSH antagonists for improved cattle reproduction and a potential $ Million annual market This work was supported by a previous phase SBIR from FDA CVM whic ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Therapies for Duchenne Muscular Dystrophy

    SBC: MYOLOGICA, LLC            Topic: NIAMS

    Project Summary Myologica is a small business focused on developing therapeutics for neuromuscular diseases Started in collaboration with the University of Maryland Myologica maintains a vigorous in house pre clinical discovery program in Duchenne Muscular Dystrophy DMD while providing consultation and specialized neuromuscular function testing for non profit and corporate clients The object ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. ZeroG TRIP Training Responses in Postural Rehabilitation

    SBC: ARETECH, LLC            Topic: NIA

    Project Summary The goal of this project is to significantly enhance our understanding and treatment of inadequate balance responses in the elderly and in patients with neurological impairments following external perturbations such as a slip or trip Our laboratory studies have shown that balance responses can be improved with practice in the elderly and in patients with Parkinsonandapos s disease ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Capsule endoscopy with 720-degree imaging capability and immersive display

    SBC: Xyken, LLC            Topic: NIA

    Project SummaryAging increases the risk of GI disorders such as CRCinflammatory bowel diseaseand appendicitisNIH statistic shows that an estimatedtomillion Americans are affected by gastrointestinal diseases annually and nearlyof older adults have one or more age related digestive symptom each yearUnfortunatelythe increasing global geriatric population base is expected to further worsen this situa ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Development and Commercialization of Predictive Biomarker Panel and In Office Kit for the Management of Diabetic Macular Edema

    SBC: OCULAR PROTEOMICS, LLC            Topic: N

    Abstract Diabetic Macular Edema DME is a vision threatening stage in Diabetic Retinopathy DR that can result in legal blindness The biochemical mechanisms that drive DME progression are not well understood and treatments address only portions of the disease pathology The available treatment options vary widely from injectable anti VEGF to injectable steroids to laser treatments and carry a ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. An innovative interactive mHealth smartphone app to improve reproductive health outcomes for minority male teens providing medically accurate information for prevention of pregnancy HIV and STIs

    SBC: MetaMedia Training International, Inc.            Topic: NCCDPHP

    Abstract MetaMedia and partner Healthy Teen Network will develop a mobile application aimed at reducing teen pregnancy and sexually transmitted infections STIs among Latino and African American men aged In the U S teen pregnancy teen births and STIs affect African American and Latino youth in greater proportion compared to other youth A comprehensive literature search revealed that ...

    SBIR Phase I 2017 Department of Health and Human ServicesCenters for Disease Control and Prevention
  8. Poly Metallo Liothyronine Complexes for Hypothyroidism Treatment

    SBC: Synthonics, Inc.            Topic: 200

    The work described in this proposal addresses the clinical deficiency of the currently available oral treatments for hypothyroidism Approximately of persons suffering from hypothyroidism report insufficient symptomatic improvement from levothyroxine T Synthroid alone This is thought to be related to a genetic variation in the enzyme that converts T to T the active form of thyroid hor ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a Novel Plasma Based Microsatellite Instability Diagnostic for Guiding Immunotherapy

    SBC: Personal Genome Diagnostics Inc.            Topic: 102

    Abstract Immune checkpoint inhibitors have recently emerged as a revolution in cancer care providing the potential for durable response and improved survival for numerous cancer patients across multiple cancer types However only of patients who are treated with checkpoint inhibitors have responded in most cancer types necessitating biomarker assays that can reliably and accurately ident ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a companion diagnostic to predict response to cetuximab in patients with head and neck squamous cell carcinoma

    SBC: Biomarker Strategies, LLC            Topic: 100

    ABSTRACT Head and neck squamous cell carcinoma HNSCC is the world s th leading cause of cancer accounting for of cancer mortality For many other cancers molecular characterization has led to sub classification of disease based on the status of oncogenic drivers in signal transduction pathways leading to the development of molecularly targeted agents MTAs targeting specific dysregulate ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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