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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Topic 368: Biotherapy of Brain Tumors by Radioiodinated SapC-DOPS Nanovesicles

    SBC: Molecular Targeting Technologies, Inc.            Topic: NCI

    There is an urgent need for more effective drug delivery agents for treatment of brain tumors, which are among the most aggressive and intractable cancers. SapC-DOPS, a nanovesicle composed of saposin C (SapC) coupled to dioleoylphosphatidylserine (DOPS), has proven tumor targeting properties, which include crossing the blood-brain tumor barrier and binding the lipid tumor marker, extracellular ph ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. TOPIC 363: myCare2- Supporting Caregivers and Caregiving

    SBC: BRIGHTOUTCOME INC.            Topic: NCI

    The myCare2 solution will be marketed to cancer care organizations and include three separate portals for cancer caregivers, patients and providers. The system will be mobile-enabled and support standards-based EHR integration. Primary myCare2 features include symptom assessment, communication with the care team, care plan dissemination, tailored education content for caregiving and for caregiver ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Topic 364: SysMet: Integrative Systems Metabolomics

    SBC: OmicsCraft LLC            Topic: NCI

    Metabolomics plays an indispensable role in the growing systems biology approaches to identify reliable cancer biomarkers. Liquid chromatography coupled to mass spectrometry (LC-MS) and gas chromatography coupled to mass spectrometry (GC-MS) have been extensively used for high-throughput comparison of the levels of thousands of metabolites among biological samples. However, the potential values of ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. TOPIC 360: A SIMPLE END-TO-END SYSTEM FOR SERIAL CELL SORTING AND MANIPULATION USING A SINGLE CONTAINER

    SBC: DIAGNOLOGIX, LLC            Topic: NCI

    Chemotherapy may control but rarely cure metastatic cancers. Remarkably, modern immunotherapies, including cell-based therapies, have cured metastatic melanomas and other types of cancers. A major challenge for all cell therapies in general is the need to develop cost-effective and efficient manufacturing and delivery capabilities. We have recently established an innovative cell isolation technolo ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. TOPIC 356: FLOUROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION

    SBC: Lucerna Inc.            Topic: NCI

    Circular RNAs (circRNAs) are a novel class of non-coding RNAs that are an abundant component of the epitranscriptome. Putative functions of circRNAs, include miRNA sequestration, RNA-binding protein scaffolding, mRNA trapping, and protein translation regulation. Deregulation in one or more of these roles has been linked to several types of cancer, including pancreatic cancer, basal cell carcinoma, ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Shallow Water Bathymetric Survey Systems

    SBC: CREARE LLC            Topic: 829

    TECHNICAL ABSTRACT: Ship groundings can cause sever environmental damage to the delicate ecosystems such as coral reefs, seagrass beds, and beaches. At present, survey work is performed by hand – a method that is inefficient and difficult to perform reliably. Improved bottom survey tools are clearly needed to evaluate the extent and type of damage and assist in determining remediation efforts. ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  7. Compact, Lightweight Open-Path Cavity RingdownSpectrometry System for UAS Deployment

    SBC: Nikira Labs Inc.            Topic: 841

    TECHNICAL ABSTRACT: In this Small Business Innovative Research (SBIR) program, Nikira Labs Inc. proposes to miniaturize the patented, open-path cavity ringdown spectroscopy (CRDS) analyzer developed by the National Oceanic and Atmospheric Administration (NOAA). The resulting instrument will be used to measure the optical properties of aerosols aboard Unmanned Aerial Systems (UASs) in highly humidi ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  8. Clean Energy from Air-Sea Temperature Differences

    SBC: SEATREC, INC.            Topic: 8211

    TECHNICAL ABSTRACT: We will demonstrate the feasibility and commercial applicability of a novel energy harvesting system that converts thermal energy from air-sea temperature differences into electricity. This capability will extend the endurance and capability of NOAA observing platforms, reduce lithium battery waste, increase human and environmental safety, and support efforts to detect and moni ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  9. Under Keel Clearance Management in Support ofPrecision Navigation

    SBC: W R SYSTEMS LTD.            Topic: 828

    TECHNICAL ABSTRACT: WR’s approach involves design of a modular, S-129 compliant Under Keel Clearance - Risk Management System (UKC-RMS). This will allow for the Electronic Chart Display and Information System (ECDIS), ECS, PPUs, and other situational awareness applications to have S-129 Exchange Sets developed for a planned route.In WR’s design, a system such as an ECDIS generates an S40X Rout ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  10. Autonomous Meteorological Measurement System

    SBC: CREARE LLC            Topic: 8212

    TECHNICAL ABSTRACT: NOAA and the National Weather Service maintain an immense network of automated maritime, surface, and upper-air observing stations throughout the world and at great expense. These automated stations provide regularly updated data for both short-term weather prediction and long-term climate models. Maritime and surface observations occur as frequently as every 10 to 20 minutes, ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration

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