Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. "BUCCAL DRUG DELIVERY SYSTEM FOR CANCER PAIN MANAGEMENT

    SBC: Anesta Corpon            Topic: N/A

    WORLDWIDE, IT IS ESTIMATED THAT 4.3 MILLION PEOPLE DIE OF CANCER EACH YEAR AND THAT ROUGHLY 70 PERCENT OF THE TERMINALLY ILL CANCER PATIENTS EXPERIENCE PAIN AS A MAJOR SYMPTOM DURING THE COURSE OF THEIR DISEASE. EVEN THOUGH THE MAJORITY OF THESE PATIENTS RECEIVE OPIOIDS FOR PAIN MANAGEMENT, UP TO 30 PERCENT STILL EXPERIENCE BREAKTHROUGH PAIN THAT IS CONSIDERED MODERATE TO SEVERE. THE GOAL IS TO DE ...

    SBIR Phase I 1991 Department of Health and Human Services
  2. "Xenopus Microarrays: A Tool for Molecular Toxicology"

    SBC: DETROIT R & D, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Each year, approximately 120,000 babies are born in the US with a major birth defect and genetic and environmental factors play an important role. Embryonic differentiation pathways are highly conserved among vertebrates. The Xenopus laevis embryo is an established toxicology model with ease of chemical exposure. Inter-laboratory studies demonstrated the reliab ...

    SBIR Phase I 2003 Department of Health and Human Services
  3. 1-D Titania Nanostructure Based Wearable Alcohol Sensor with Tunable Sensitivity and Artificial Intelligence

    SBC: NanoSynth Materials and Sensors Inc.            Topic: 450

    PROJECT SUMMARY The overarching goal of this proposal is to develop an artificially intelligent alcohol sensor that is wearablenoninvasivesmartand aestheticThe aimin Phase Iis to design and develop the alcohol sensor based on metali eCobaltfunctionalized Titanium nanotubesTiNTto detectmonitorand display blood alcohol levels in real time using microcontrollers based wrist band like devicesAt the co ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. 12-Lipoxygenase as a Target for Radiosensitization

    SBC: Biomide Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): The arachidonic acid (AA) lipoxygenase pathway plays an important role in tumor progression through regulating cell survival, proliferation, and angiogenesis. Prostate cancer (PCa) is the most commonly diagnosed neoplasm and the second leading cause of male death in the United States. During PCa progression, it is found that the expression of 12-lipoxygenase ...

    SBIR Phase I 2005 Department of Health and Human Services
  5. 2-Clinic Feasibility Study: Inverse Scatter Breast Scan

    SBC: TECHNISCAN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase-l SBIR project, of a Fast Track pair, will provide concept testing, computer simulation studies, laboratory-based hardware emulation and a final specification for the final scanner to be constructed in the Phase ll SBIR project. The result of this Fast Track effort is intended to be used as the foundation, starting specifications and design for the c ...

    SBIR Phase I 2006 Department of Health and Human Services
  6. 2-Phase Nanogels for Quantitative 3D Radiation Dosimetry

    SBC: MGS RESEARCH INCORPORATED            Topic: N/A

    MGS Research has pioneered the development of polymer gel dosimeters, using both MRI and optical CT scanning. Our goal in Phase I will be to prove the feasibility of an innovative two-phase nanostructured polymer gel for quantitative 3D radiation dosimetry. The new gel structure can be described as a "single-hit 3D photon counter" that can be expected to be linear with dose and to be dose-rate in ...

    SBIR Phase I 2003 Department of Health and Human Services
  7. 2D HOLLOW ARRAY SOLID MEMBRANE FOR BLOOD OXYGENATORS

    SBC: Michigan Critical Care Consultants, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1997 Department of Health and Human Services
  8. 3D ULTRASOUND COMPUTED TOMOGRAPHY BREAST IMAGING SYSTEM

    SBC: ULTRASOUND DETECTION SYSTEMS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): X-ray mammography is the standard for the detection of breast cancer. Mammography is not ideal due to its use of ionizing radiation, its superposition artifacts, its inability to differentiate malignant from benign lesions, and its inability to detect 8-22% of palpable breast cancers. Echo ultrasound imaging is used as an adjunct to mammography for the determin ...

    SBIR Phase I 2002 Department of Health and Human Services
  9. A Bacitracin derivative for systemic use

    SBC: AUREOGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The number of patients treated for antibiotics-resistant infections has increased drastically in recent years. What started as a problem primarily associated with hospital-acquired Enterococcus infections, has not only moved into the general community, but also grown to include a number of widespread and serious pathogens. Drug-resistant Streptococci, Staphyloc ...

    SBIR Phase I 2007 Department of Health and Human Services
  10. A bifunctional antibody screening system for both phage display and yeast two-hyb

    SBC: AFFOMIX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): This is a proposal to establish a proof-of-principle for a vector system to isolate high-affinty antibodies through selective rounds in both yeast and Escherichia coli. Antibodies have quickly become extremely useful as therapeutic medicines to treat a wide-variety of disorders. We propose to develop a means of making the discovery of immunotherapeutics faster ...

    SBIR Phase I 2010 Department of Health and Human Services
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