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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Plasma-assisted atomic layer deposition of alumina and Parylene-C bi-layer encaps

    SBC: BLACKROCK MICROSYSTEMS, INC            Topic: NIBIB

    DESCRIPTION provided by applicant A range of neurological diseases are now being researched or treated using fully implantable electronic systems to either record or modulate brain activity in humans These implants are currently being protected using polymer coatings that envelop the implant and help keep body fluids away from the sensitive electronics Brain implants with complex three dimens ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Development of the VirtualTAVR system for diagnostics and preventative strategies

    SBC: Dura LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Since the first procedure in there has been an explosive growth in transcatheter aortic valve replacement TAVR Up to date more than TAVR had been performed worldwide Despite the increased global experience with TAVR severe adverse events associated with TAVR have been extensively documented including annulus rupture coronary occlusion para ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Cost-effective MHz rate Optical Coherence Tomography for biomedical applications

    SBC: WASATCH PHOTONICS, INC.            Topic: NIBIB

    DESCRIPTION provided by applicant During this SBIR Phase I project we propose to build and test in phantoms a prototype of an innovative cost effective Optical Coherence Tomography OCT system with a X increase in acquisition rate compared to commercially available systems Further development may add an additional X increased acquisition rate for a total of X Current market demand for ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Novel ELISA Kit for Screening Potential JAK3 Inhibitors

    SBC: Twenty First Century Therapeutics, Inc.            Topic: 300

    DESCRIPTION provided by applicant Janus kinase JAK is an intracellular kinase involved in cytokine and antibody receptor signaling it is frequently over activated during the course of inflammatory autoimmune diseases Therefore suitable JAK inhibitors that modulate the overexpression of JAK may be potential agents for treating autoimmune diseases Logically it is of significant import ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Nucleoside Phosphonate Analogs for the Treatment of Adenoviral Infection

    SBC: TSRL, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Adenovirus can be a significant health risk for immune compromised patients both adult and pediatric patients In pediatric patients in particular complications associated with adenoviral infection include pneumonia urinary infections and hepatitis In the military setting adenoviruses are endemic in Department of Defense basic recruit training installation ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Extending an Open-Source Integrated Data Management Platform to Anxiety Disorders

    SBC: PROMETHEUS RESEARCH, LLC            Topic: 101

    DESCRIPTION provided by applicant The goal of this application is to empower anxiety disorders researchers to manage share and repurpose their research data more effectively throughout the research lifecycle by delivering an open source integrated data management platform that meets their needs Mental health research has become more complex collaborative and interdisciplinary and sharing ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Sustainable, Multi-Seasonal, Multi-Species, Marine Algal Aquaculture in Coastal Maine

    SBC: Maine Fresh Sea Farms, LLC            Topic: 81

    This Phase I proposal determines the feasibility of growing multiple species of macroalgae in commercial marine aquafarm environments. Marine aquaculture is a logical outgrowth of successful wild harvest seaweed businesses over the last several years. Developing a marine aquaculture prototype will foster the science of sea farming. Extending growing seasons for multi-species would provide year ...

    SBIR Phase I 2014 Department of CommerceNational Oceanic and Atmospheric Administration
  8. Targeted Inactivation of the CCR5 HIV Coreceptor with Peptide Nucleic Acids

    SBC: L2 DIAGNOSTICS LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Over 34 million people are currently living with HIV/AIDS. Combination antiviral therapies have significantly reduced the morbidity and mortality of the disease; however, there is currently no cure for the disease. Discovery that a naturally occurring variant of CCR5, the delta32 mutation, renders cells resistant to HIV infection has led to efforts by several a ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Formulation of LbL microparticle vaccine in microneedle array for intradermal del

    SBC: ARTIFICIAL CELL TECHNOLOGIES INC            Topic: NIAID

    Abstract The ability of the immune system to recognize and initiate an immune response to foreign particles such as bacteria and viruses has generated interest in development of particulate vaccine technologies. We are developing an innovative approach toproduce particulate vaccines via layer-by-layer (LbL) fabrication of synthetic microparticles (MP). We have shown that LbL-MP loaded with epitope ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. A Quantum Similarity Approach for the Discovery of Anti-Trypanosome Drug Leads

    SBC: GRADIENT BIOMODELING, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Human African trypanosomiasis (HAT) is an infectious disease with a large global health burden occurring primarily in Central and Eastern Africa. HAT is 100% fatal if untreated and the current drug therapies suffer frompoor safety profiles, difficult treatment regimens, limited effectiveness, and high costs. Furthermore, drugs that cross the blood brain barrier ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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