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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Quantitative Handwriting Assessment Tool for Healthy and Impaired Children
SBC: NEWVENTUREIQ LLC Topic: NICHDNo technology currently exists for objective assessment of handwritingeven though overmillion individuals in the United States suffer from disorders that affect handwritingincludingmillion children with dyspraxia and overolder adults with Parkinsonandapos s diseaseThis lack of assessment technology creates a barrier to effective carebecause occupational therapists cannot easily distinguish motor d ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A Noninvasive Platform to Assess Maternal Risk for Perinatal Complications in the First Trimester
SBC: Cradle Genomics, Inc. Topic: NICHDLimited information is available about early human placentation when many pregnancy pathologies originateTo address this knowledge gap and begin development of robust diagnostic tool to manage pregnancy complicationswe propose a pilot study based on a highly sensitive immune assay and our company s base technologyTrophoblast Retrieval and Isolation from the CervixTRICTRIC uses a Pap smearconsidere ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A therapeutic approach for potential prevention of aromatase inhibitor-induced bone loss
SBC: NANOMEDIC INC Topic: NIAAbstractIn this SBIR Phase I applicationour goal is to demonstrate proof of concept of our lead chelating agent as a potential therapeutic for the prevention of osteoporosis induced by aromatase inhibitorAItherapy in postmenopausal women with hormone receptor positive breast cancerAlthough AI therapy shows great improvements in cancer free and overall survivalits treated patients face a risk of os ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Optimizing Direct Delivery of Nucleic Acid Therapeutics
SBC: FHC, INC. Topic: NIMHProject Summary While nucleic acid therapeutics have shown promise in rodent and nonhuman primate models of CNS diseasesall double blind clinical trials to date have failedOne likely explanation for this failure is poor therapeutic distribution in targeted brain regionsFor examplepost mortem studies of patients with Parkinsonandapos s Disease receiving intraparenchymal injections of AAV NTN demons ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Novel Tetrahedron Beam CT for Point-of-Care Imaging in Ear, Nose, and Throat
SBC: TETRAIMAGING LLC Topic: NIBIBABSTRACT Point of care imaging is highly desired in otolaryngologic clinics for the diagnosis of earnose and throatENTdiseases including cancersDue to limited image qualitycurrent cone beam CTCBCTproducts act not as a substitute but rather as a complement to diagnostic Multi slice CTMSCTin maxillofacial and ENT imagingThe emerging multi source x ray source technology suggests new designs of CT sys ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A Deep Learning Model to Improve Pathologist Interpretation of Donor Kidney Biopsies
SBC: NEWVENTUREIQ LLC Topic: 300PROJECT SUMMARY ABSTRACT More people die every year from kidney disease than breast or prostate cancerKidney transplantation is life saving but is limited by a shortage of organ donors and an unacceptably high donor organ discard rateThe decision to use or discard a donor kidney relies heavily on manual quantitation of key microscopic findings by pathologistsA major limitation of this microscopic ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Daily and localized NSAID sonophoresis for symptomatic treatment of knee osteoarthritis
SBC: Zetroz Systems LLC Topic: NIAProject SummaryOsteoarthritisOAis the most common type of arthritisaffecting overmillion adults in the United States inand represents overof medical office visits according to the Centers for Disease Control and Prevention and the National Institutes of HealthOverof individuals overhave symptomatic OA and reduced mobility due to the diseaseOA pain is often mitigated with conservative treatment app ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Establishing the POROS Intracellular Delivery System as a Platform for Cellular Therapeutics
SBC: OPENCELL TECHNOLOGIES, INC. Topic: 100Abstract SignificanceIntracellular delivery of nucleic acids to immune cells is an important component of many current and anticipated cellular therapiesincluding chimeric antigen receptor T CellCAR Ttherapies for the treatment of cancerThese therapies use immune cells called T cellseither from the patient themselvesor a healthy donorand genetically engineer them to kill the tumor cellsThe genetic ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Single-cell Phosphoprotein Assay to Evaluate Brain Tumor Therapeutic Resistance
SBC: ISOPLEXIS CORPORATION Topic: 102Although signal transduction inhibitors occasionally offer clinical benefit for cancer patientssignal flux emanating from oncogenes is often distributed through multiple pathwayspotentially underlying the resistance which causes failure of most such inhibitorsMeasuring signal flux through multiple pathwaysin response to signal transduction inhibitorsmay help uncover network interactions that contr ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Use of Stem Cells to Enhance and Extend Continuous Glucose Monitoring in Vivo
SBC: Cell And Molecular Tissue Engineering LLC Topic: 200Implantable glucose sensor based monitoring of blood glucose levels in diabetic patients has been available for overyearsHoweverdespite improvements to sensor functionalityrecalibration of the sensor device is often a necessity in order to compensate for unreliable sensor performanceThe development of highly accurate and long lived implantable sensors is critical to the development of theartificia ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health