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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Microneedle Delivery of Zanamivir for Treatment of Influenza Infections

    SBC: TSRL, INC.            Topic: NIAID

    Abstract Yearly influenza epidemics strike millions of peoplecausing up todeathsFatality caused by most seasonal influenza viruses is ltbut with significant mortality in the young and the elderly populationsWhen a new pathogenic influenza strain enters the populationa pandemic could kill tens of millions of people with a negative economic impact estimated to be overbillion dollarsInfluenza virus i ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. A Rapid Low Cost Point of Care Diagnostic for detection of Zika virus RNA

    SBC: L2 DIAGNOSTICS LLC            Topic: NIAID

    ABSTRACT Zika virus ZIKV has rapidly emerged and spread through South and Central America the Caribbean and Puerto Rico since its last outbreak in Micronesia in Transmitted by the mosquito Aedes sp its forecasted spread will have a major impact on the Southeast U S Most ZIKV infections remain asymptomatic or present with non specific rash and fever therefore they have been difficult ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. High throughput multiplexed characterization and modeling of antibody antigen binding with application to HSV

    SBC: Carterra, Inc.            Topic: NIAID

    Abstract All therapeutic antibodies and most vaccines critically depend on the ability of antibodies to specifically recognize particular antigens consequently detailed characterization of antibody antigen binding can provide invaluable information to understand and guide development Unfortunately due to the time and expense required atomic resolution structure determination is typically use ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a DNA Aptamer Based Electrochemical Assay for Acetazolamide in Urine Using a Handheld Biosensor for Compliance Validation in Clinical Drug Trials

    SBC: ApolloDx , LLC            Topic: NIDA

    Development of a DNA Aptamer Based Electrochemical Assay for Acetazolamide in Urine Using a Handheld Biosensor for Compliance Validation in Clinical Drug Trials Thirty to over eighty percent of patients enrolled in pharmaceutical clinical trials do not comply with trial protocols by discarding the drug under investigation or not using the proper dosages This common practice compromises the medica ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Geostatistical software for space-time interpolation and uncertainty modeling

    SBC: BIO-ANALYTICS, INC.            Topic: NIEHS

    DESCRIPTIONprovided by applicantA key component in any investigation of association and or cause effect relationships between the environmente gair pollutionheat wavesand health outcomese gasthmaheart diseasecanceris the availability of accurate models of exposure at the same geographical scale and temporal resolution as the health outcomesThe computation of human exposure is particularly challeng ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. De-risking ONL1204 to enable venture capital investment for first-in-human clinical trials

    SBC: ONL Therapeutics, Inc.            Topic: NEI

    PROJECT SUMMARYABSTRACTRetinal degenerative disease and injury are among the leading causes of irreversible vision loss and blindness in the United States and the developed worldaffecting hundreds of thousands of people every year and resulting in billions of dollars in added healthcare costs and lost productivityPhotoreceptor cell death is a consequence of many of these acute and chronic retinal ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Development of MTX for the Treatment of KRAS Mutant Colorectal Cancer

    SBC: Mekanistic Therapeutics, LLC            Topic: NCI

    PROJECT SUMMARY Mekanistic Therapeutics seeks to design discover and develop anti cancer agents that selectively inhibit multiple oncogenic pathways Its lead agent MTX was discovered in collaboration with the Leopold laboratory at University of Michigan MTX is a novel kinase inhibitor showing early promise for its therapeutic potential against solid cancers refractory to current treatm ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a nanoemulsion-adjuvanted prophylactic HSV-2 vaccine

    SBC: BLUEWILLOW BIOLOGICS INC            Topic: R

    ABSTRACT Genital herpes simplex virusHSVinfections are a major public health problem affecting rtmillion people in the United States and rtmillion globallyHSVinfection causes recurringgenital sores that are painful and result in considerable psychological distressTransmission can occur during sexual contact and from mother to child during birth with fatal consequencesThere is no effective vaccine ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Commercial Software Using High throughput Computational Techniques to Improve Genome Analysis

    SBC: Genomenon, Inc.            Topic: 172

    Recent advances in DNA sequencing technology have not been matched by improved analytic techniques to quickly and accurately interpret patient genome data to inform diagnosis prognosis and therapy making decisions in the clinic and to identify candidate biomarkers of disease in research laboratories Development of automated techniques to facilitate interpretation of this data will benefit patien ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Tools for Faster and Cheaper Delivery of Integrated Registries

    SBC: PROMETHEUS RESEARCH, LLC            Topic: 103

    The goal of this project is to enable fastercheaper delivery of integrated registries for mental health research centers by improving the Research Exchange DatabaseRexDBan open source integrated registry platform developed by Prometheus Research during a prior Phase I SBIR awardIntegrated research registries can provide many benefits to mental health researchers and organizationsincluding easier d ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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