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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Adaptive Clinical Efficacy Evaluation of ONC201 in Recurrent High Grade Glioma

    SBC: Oncoceutics, Inc.            Topic: 102

    Project Summary We propose a two-arm adaptive Phase II clinical trial to evaluate ONC201, a selective antagonist of the G protein-coupled receptor (GPCR) dopamine receptor domain 2 (DRD2), in recurrent glioblastoma (GBM) and diffuse midline glioma associated with very poor prognoses and limited treatment options. DRD2 is overexpressed in high grade gliomas and controls Akt/ERK signaling pathways. ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Topic 368: Biotherapy of Brain Tumors by Radioiodinated SapC-DOPS Nanovesicles

    SBC: MOLECULAR TARGETING TECHNOLOGIES, INC.            Topic: NCI

    There is an urgent need for more effective drug delivery agents for treatment of brain tumors, which are among the most aggressive and intractable cancers. SapC-DOPS, a nanovesicle composed of saposin C (SapC) coupled to dioleoylphosphatidylserine (DOPS), has proven tumor targeting properties, which include crossing the blood-brain tumor barrier and binding the lipid tumor marker, extracellular ph ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Enhanced Canine Performance, Protection and Survivability

    SBC: Metro International Biotech, LLC            Topic: SOCOM172002

    Given the benefits of exercise on general health, orally active compounds that can mimic or potentiate the effects of exercise have been of keen interest as therapeutic and dietary ingredients. Our proposed approach for enhancement of USSOCOM Multi-Purpose Canine (MPC) endurance and sensory performance using an exercise mimetic is based on the observation that age-related decline of nicotinamide ...

    SBIR Phase I 2018 Department of DefenseSpecial Operations Command
  4. Group 2 (<55lbs) Unmanned Aerial System for Special Operations Forces Tactical-Level Intelligence, Surveillance, and Reconnaissance Operations

    SBC: SEALANDAIRE TECHNOLOGIES, INC.            Topic: SOCOM172005

    SeaLandAire Technologies, Inc. (SLA) proposes to meet this Group 2 need with an electric drive concept that will be capable of a 20-30 lbs. modular payload, with comparable range and endurance to current grp 2 ISR UAS, while still maintaining sufficient ISR capabilities. This UAS concept is able to covertly and safely deliver payload to within 1 meter accuracy, then extract a different payload an ...

    SBIR Phase I 2018 Department of DefenseSpecial Operations Command
  5. WesTest Hardware Modeler for LASAR Digital Device Simulationcompatible with the VDATS Di-Series digital subsystem

    SBC: WESTEST ENGINEERING CORP            Topic: AF172005

    Many custom and hybrid integrated circuits (ICs) and custom electronic components cannot bemodeled in simulation software because of their complexity and/or lack of technical data.TPS developers need to use a hardware modeler for these types of integrated circuits.The proposed WesTest Hardware Modeler will be compatible with LASAR and the VDATS Di-Series digital subsystem.It utilizes the Teradyne ...

    SBIR Phase I 2018 Department of DefenseAir Force
  6. Tape-Wrapped Carbon / Silicon Carbide Composites for Launch Vehicle Applications

    SBC: MATERIALS RESEARCH & DESIGN INC            Topic: AF173008

    To ensure continued access to orbit for United States government and commercial payloads, attractive replacement candidates for foreign-made propulsion components must be identified and the associated technology matured. The innovation proposed herein will identify and further maturation of a domestically available, oxidation-resistant, high-temperature C/SiC material candidate for launch vehicle ...

    SBIR Phase I 2018 Department of DefenseAir Force
  7. Advanced IM Compliant Dual-Mode Energetic System

    SBC: Systima Technologies, Inc.            Topic: AF173012

    Systima Technologies, Inc. in collaboration with Aerojet Rocketdyne is proposing to develop and demonstrate a dual mode energetic system design that incorporates an advanced energetic formulation, technology for burn-rate control, and features for IM compliance and system performance enhancement (lethality).The Phase I program includes development and refinement of the system design concepts, comp ...

    SBIR Phase I 2018 Department of DefenseAir Force
  8. Reconstruction Algorithms for High-Energy Computed Tomography Images of Rocket Motors

    SBC: LICKENBROCK TECHNOLOGIES, INC.            Topic: AF121187

    In the Phases I and II of this SBIR project, a software product was developed, delivered and deployed at the Hill AFB CT facility for highly resolving computed tomography of aerospace components.The project was focused upon speed of execution using high-performance computer architectures.In this commercialization readiness program, the technology will be advanced to at least TRL 6 by the following ...

    SBIR Phase II 2018 Department of DefenseAir Force
  9. Just In Time (JIT) Aircraft Maintenance System

    SBC: CYBERNET SYSTEMS CORPORATION            Topic: AF121225

    Roughly 40% of USAF maintenance records have poorly coded work unit codes. This degrades aircraft pre-induction analysis and fleet-wide analysis of top drivers. Manual methods to scrub the data take years to develop for each air platform. Cybernet designed a machine learning algorithm to automatically correct coding errors without expert input. The Smart Data Cleanser (SDC) performed 4 years of wo ...

    SBIR Phase II 2018 Department of DefenseAir Force
  10. Hypersonic Data Recovery

    SBC: Systima Technologies, Inc.            Topic: AF151180

    Systima Technologies, Inc. proposes the development of an unmanned hypersonic test vehicle recovery system that will greatly enhance the effectiveness of hypersonic flight testing. Systima plans to perform a comprehensive review of the various hypersonic vehicle test environments and recovery requirements in order to develop recommendations for suitable vehicle recovery technologies for the range ...

    SBIR Phase II 2018 Department of DefenseAir Force
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