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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Adaptive Clinical Efficacy Evaluation of ONC201 in Recurrent High Grade Glioma

    SBC: Oncoceutics, Inc.            Topic: 102

    Project Summary We propose a two-arm adaptive Phase II clinical trial to evaluate ONC201, a selective antagonist of the G protein-coupled receptor (GPCR) dopamine receptor domain 2 (DRD2), in recurrent glioblastoma (GBM) and diffuse midline glioma associated with very poor prognoses and limited treatment options. DRD2 is overexpressed in high grade gliomas and controls Akt/ERK signaling pathways. ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Topic 368: Biotherapy of Brain Tumors by Radioiodinated SapC-DOPS Nanovesicles

    SBC: MOLECULAR TARGETING TECHNOLOGIES, INC.            Topic: NCI

    There is an urgent need for more effective drug delivery agents for treatment of brain tumors, which are among the most aggressive and intractable cancers. SapC-DOPS, a nanovesicle composed of saposin C (SapC) coupled to dioleoylphosphatidylserine (DOPS), has proven tumor targeting properties, which include crossing the blood-brain tumor barrier and binding the lipid tumor marker, extracellular ph ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Innovative Technologies for High Power Amplification at THz frequencies

    SBC: CARLEY TECHNOLOGIES, INC            Topic: SB162006

    The objective of the proposed project is to develop designs for manufacturable all-metal terminal hot-electron transistors (AMTHETs) that will enable 1W – 10W THz RF amplifiers and oscillators. The proposed work will focus on quantum-mechanical modelin...

    SBIR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency
  4. Explainable AI to support Veterans Transition Assistance Programs (XAI-VTAP)

    SBC: SOAR TECHNOLOGY INC            Topic: SB163007

    A challenge for Artificial Intelligence recommenders is explaining their reasoning to users. Humans tend to explain concepts with symbolic narratives, which contrasts the way non-symbolic machine learning represents concepts. This research addresses this challenge by grounding the research in the problem of helping transitioning veterans find relevant careers. The developed prototype will provide ...

    SBIR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency
  5. Advanced Technologies for Reducing Decompression Obligation and Risk

    SBC: CREARE LLC            Topic: SB131004

    Despite over 100 years of research, decompression sickness (DCS) remains the mission-limiting factor in the design and execution of combat diving operations.Divers may spend over an hour decompressing after spending as little as ten minutes at the target depth.While decompressing, divers are limited in vertical mobility, making then susceptible to detection and threatening their survivability.This ...

    STTR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency
  6. Shallow Water Bathymetric Survey Systems

    SBC: CREARE LLC            Topic: 829

    TECHNICAL ABSTRACT: Ship groundings can cause sever environmental damage to the delicate ecosystems such as coral reefs, seagrass beds, and beaches. At present, survey work is performed by hand – a method that is inefficient and difficult to perform reliably. Improved bottom survey tools are clearly needed to evaluate the extent and type of damage and assist in determining remediation efforts. ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  7. Autonomous Meteorological Measurement System

    SBC: CREARE LLC            Topic: 8212

    TECHNICAL ABSTRACT: NOAA and the National Weather Service maintain an immense network of automated maritime, surface, and upper-air observing stations throughout the world and at great expense. These automated stations provide regularly updated data for both short-term weather prediction and long-term climate models. Maritime and surface observations occur as frequently as every 10 to 20 minutes, ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  8. Development of “Permit Wizard” Software for AssistedPermit Application Completion

    SBC: TOTAL QUALITY SYSTEMS, INC.            Topic: 833

    TECHNICAL ABSTRACT: The objective of this project is to research the technical feasibility of designing a software tool “Permit Wizard” that will automate the process for aquamarine permit application submittal, review, approval/disapproval and issue (including collection of fees). Aquaculture producers are currently faced with slow, complex, and often confusing permitting processes that must ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  9. Clean Energy Source to Power NOAA Long-termObservation and Monitoring Networks

    SBC: CREARE LLC            Topic: 8211

    TECHNICAL ABSTRACT: Creare proposes to develop a self-sustained small-scale power conversion system to power NOAA’s weather monitoring network stations located in harsh uninhabited locations. Our miniature heat engine will take advantage of the existing year-round thermal gradients found between water and air in Arctic regions. Our baseline approach is the development of a compact Turbo-Rankine ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  10. Doppler Wind Temperature Sounder

    SBC: BRANDYWINE PHOTONICS LLC            Topic: 8212

    TECHNICAL ABSTRACT: We propose developing a new observational capability for measuring upper atmosphere (20-Km to 200-Km+ altitude) wind and temperature dynamics, based on Doppler imaging of Limb concentrations of NO, N2O, and CO2 called the Doppler Wind Temperature Sounder. The principle of operation is that by measuring the Doppler shift of trace gases created by the differential velocity betwee ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
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