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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Polynitroxylated Pegylated Hemoglobin for Traumatic Brian Injury Resuscitation

    SBC: SYNZYME TECHNOLOGIES LLC            Topic: 102

    DESCRIPTION provided by applicant Traumatic brain injury TBI is a leading cause of morbidity and mortality especially when complicated by secondary insults such as hypotension Vulnerability of TBI patients to hypotension is well recognized and identifies a key need for new approaches The goal of this proposal is to develop to IND a neuroprotective hyper colloid oxygen therapeutic polynit ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Rapid, reliable and repeatable platforms for cell-free prototyping

    SBC: SYNVITROBIO, INC.            Topic: SB152001

    Cell-free platforms are a disruptive technology that can dramatically speed up the design-build-test cycle of biomolecular engineering. However, most currently available cell-free platforms are optimized for protein expression rather than for prototyping. Synvitrobio proposes to develop and commercialize a next-generation cell-free platform that allows for rapid, low-cost, high-throughput, and rep ...

    SBIR Phase I 2016 Department of DefenseDefense Advanced Research Projects Agency
  3. Phosphodiesterase-4B (PDE4B) Inhibitors for Alzheimer's Disease

    SBC: Tetra Discovery Partners, Inc.            Topic: 101

    Under the parent grantTetra Discovery Partners is developing phosphodiesteraseBPDE Ballosteric inhibitors as a treatment for major depressive disorderUniquelythe Tetra drug will address inflammation as a contributor to depressionThis is a new mechanism of action for an antidepressant drug which should prove complimentary to current therapeuticsThe company estimates thatof patients with depression ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. A high resolution and high DQE detector optimized for mammography using single shot bi directional tri contrast imaging

    SBC: SIGRAY, INC.            Topic: NIBIB

    DESCRIPTION provided by applicant X ray tricontrast imaging provides three different modes of contrast absorption contrast the mechanism behind how conventional medical X ray imaging equipment images phase contrast which provides up to X more contrast than absorption based contrast for soft tissue and scatter contrast which provides information of features at dimensions smaller than ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a fiber optic high dynamic range magnetic field gradiometer operable in unshielded environments

    SBC: TIPD LLC            Topic: SB161005

    Proposed, is a low cost fiber optic high dynamic range magnetic field gradient measurement system for noninvasive, real-time monitoring of bio-magnetic activities with high spatiotemporal resolution in unshielded environment. Each gradient measurement system would consist of 1 scalar magnetometer, 1 each of horizontal and vertical gradiometers, and additional scalar magnetometers for background ma ...

    SBIR Phase I 2016 Department of DefenseDefense Advanced Research Projects Agency
  6. L-Band Radio Frequency Interference Filtering

    SBC: ADAPTIVE DYNAMICS, INC.            Topic: 844

    In Phase 1, Adaptive Dynamics Inc. (ADI) propose to do a PHY layer MATLAB simulation and optimization of the 'IMPS' Wideband MAGIC® Interference Mitigation (IM) filter for NOAA. This will demonstrate the feasibility and performance of the IMPS Wideband MAGIC® IM filter algorithm in effectively identifying and separating out unwanted interference from the desired signal of interest (SOI), without ...

    SBIR Phase I 2016 Department of CommerceNational Oceanic and Atmospheric Administration
  7. Analog Co-Processors for Complex System Simulation and Design

    SBC: Arete Associates            Topic: ST15C002

    It has long been known that analog computers can be faster and more power efficient than digital processors by many orders of magnitude. Until the 1970s analog computers were the dominant controllers in most industrial and military applications. Even today digital processors are still slower and more power consumptive than analog, but offer much more flexibility (programmability) and precision. ...

    SBIR Phase I 2016 Department of DefenseDefense Advanced Research Projects Agency
  8. Dual-view endoscopic probe

    SBC: Omniscient Imaging, Inc.            Topic: 102

    DESCRIPTION provided by applicant Colon cancer is a leading cause of cancer death in the United States and overseas Colonoscopy is the preferred screening method at an estimated annual cost of over $ billion in the US Unfortunately many lesions are missed because pre cancerous growths remain hidden from view behind folds and flexures of the colon Current methods of increasing the field of ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Small molecule inhibitors targeting oncogenic drivers of hepatocellular carcinoma

    SBC: L2 DIAGNOSTICS LLC            Topic: 102

    DESCRIPTION provided by applicant Hepatocellular carcinoma HCC is the most prevalent cancer in human population and will lead to over deaths in the United States this year alone However the molecular mechanisms driving hepatocellular carcinoma HCC growth and metastasis remain elusive and there is a huge unmet medical need to find new therapeutic targets We performed an unbiased ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Novel SCD1 inhibitors for treatment of cancer

    SBC: MODULATION THERAPEUTICS, INC.            Topic: 102

    DESCRIPTION provided by applicant Metastatic clear cell renal cell carcinoma mccRCC is an incurable cancer with a year survival of less than for which novel therapeutic agents need to be developed urgently It is notoriously resistant to chemotherapy and radiation Although molecularly targeted therapies have led to an improvement in survival the benefit is rather limited due to event ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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