Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Sea Tag-SP: A family of acoustic enabled satellite tags for spawning detection and more

    SBC: DESERT STAR SYSTEMS, LLC            Topic: 812

    Phase-1 demonstrated the powerful and unusual remote sensing opportunities available by adding acoustic signal detection to pop-up satellite tags (PSAT). The time and location of spawning define the starting point in the life history of fish. Yet this event, which is of critical importance to fishery researchers and managers seeking to gain an understanding of distinct reproductive populations and ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  2. Development of a Functional Balloon-borne GNSS-RO System Prototype

    SBC: Night Crew Labs, LLC            Topic: 811

    The SBIR Phase II proposal outlines the approach of Night Crew Labs (NCL) in designing, and developing, and testing a system prototype to perform Global Navigation Satellite System radio occultations (GNSS-ROs) from a high-altitude balloon platform. NCL will continue building from the positive results achieved in Phase I that successfully demonstrated the feasibility of performing balloon-borne GN ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  3. Fog Viewer

    SBC: Areté Associates            Topic: 826

    The presence of fog reduces visibility, contributing to unsafe conditions for many maritime tasks. The current system uses active backscatter and has high power requirements, high maintenance and replacement costs. Areté Associates’ innovative FogViewer system comprises a passive multi-spectral, multi-polarization sensor suite that leverages available degrees of freedom to best characterize the ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  4. Rapid diagnostic to determine CMV serological status

    SBC: NANOCOMPOSIX INC            Topic: NIAID

    The goal of this project is to develop a diagnostic that can support the enrollment of seronegative individuals in clinical trials of candidate cytomegalovirusCMVvaccinesCongenital CMV infection is one of the leading causes of non genetic birth defects worldwideIf a successful vaccine can be brought to marketit will have a significant impact on the number of babies born with hearing and vision los ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. SBIR PHASE II TOPIC 294:SITE-SPECIFIC ANTIBODIES FOR GLCNACYLATED PROTEINS IN CANCER; HHSN261201300058C; POP: 9/13/13-09/12/16; CAN: 8478363 IGF::OT::IGF OTHER FUNCTIONS

    SBC: DETROIT R & D, INC.            Topic: NCI

    O GlcNAcylation of proteins plays a critical role in cell cycle regulationapoptosis and signal transductionModification of O GlcNAcylation of proteins by O GlcNAc transferase is reversible by the activity of O GlcNAcaseAddition and removal of O GlcNAc moiety to serine or threonine regulate the function of proteins directly or via decreased phosphorylationO GlcNAcylation of c myc proteins induces u ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. TOPIC 369: NOVEL DOSING AND DISPENSING SYSTEM FOR MULTIPARTICULATE CANCER DRUGS

    SBC: HS-DESIGN, INC            Topic: NCI

    Oncology drugs continue to advance at a rapid pace with many therapies delivered orally as tablets or capsulesSmaller childrenhowevercannot swallow tablets or capsulesFor these drugs to be used in the pediatric population they need to be reformulatedTraditionally this has meant creating a liquid suspensionchewableor rapid dissolve tabletCancer medicationshoweveroften have terrible taste profiles t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. TOPIC 359: A DEVICE PROTOTYPE FOR ISOLATION OF MELANOMA EXOSOMES FOR DIAGNOSTICS AND TREATMENT MONITORING

    SBC: Aethlon Medical, Inc.            Topic: NCI

    The proposed work aims to develop a pre commercial prototype of an exosome isolation device to be used in clinical diagnostic laboratoriesWe will advance the device to facilitate exosome isolation for downstream liquid biopsy tests requiring analysis of proteinDNAor microRNAwhich rely upon acquisition of intact and pure exosomesThe device strategy will be designed to isolate total exosomes and the ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. TOPIC 366: I-PARTS INTEGRATED PLATFORM FOR ANTI-CANCER RADIATION THERAPEUTICS SCREENING

    SBC: PACT & HEALTH LLC            Topic: NCI

    Tumor Irradiation during cancer treatment induces clonogenic death that can be best assessed by colony forming assaysThese colony forming assays are laborious and never utilized in high throughput screeningHTSformatsWe propose to develop anintegrated platform for HTS clonogenic survival assayfor cancer drug screening as well as radiation effect modulation screeningNamedI PARTSIntegrated platform f ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. TOPIC 353: HIGHLY ACCURATE LOW COST CTDNA DIAGNOSTICS WITH MAGNETIC NANOPARTICLE ENABLED AUTOMATED SAMPLE PREP- MOONSHOT

    SBC: NVIGEN            Topic: NCI

    The goal of the research is to develop a highly accurateautomatedand low cost ctDNA test to monitor efficacy of treatment of metastatic breast cancer patients by identifying the emergence of certain DNA mutations in plasma samplesThere is growing evidence that the presence of certain DNA mutations in the blood stream correlates with breast cancer becoming resistance to hormone treatmentNVIGEN will ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. IGF::OT::IGF TOPIC 372 DEVELOPMENT AND VALIDATION OF NON-MOUSE REAGENTS TO ENABLE PRECLINICAL DEVELOPMENT OF NOVEL THERAPEUTICS- MOONSHOT

    SBC: SYNBAL, INC.            Topic: NCI

    In this Fast track SBIR grant we aimby the end of Phase IIto prepare and commercialize a fully humanized rat with Knock out of many rat drug metabolism related CYPsinout Rat Drug Metabolism CYPModeland Knock in of the human counterpartIN PHASE I we will develop an Active GenesGene DriveAG GDrata rat with a properly configured Casto power Active GeneticsAGANDwe will prepare the first CYPKout KinCYP ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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