List
The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.
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Development of the VirtualTAVR system for diagnostics and preventative strategies
SBC: Dura LLC Topic: NHLBIDESCRIPTION provided by applicant Since the first procedure in there has been an explosive growth in transcatheter aortic valve replacement TAVR Up to date more than TAVR had been performed worldwide Despite the increased global experience with TAVR severe adverse events associated with TAVR have been extensively documented including annulus rupture coronary occlusion para ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Randomized Prospective Phase II Clinical Trial of NVX in Association with Chemoradiation of Glioblastoma
SBC: NUVOX PHARMA, L.L.C. Topic: 102Glioblastoma multiforme GBM is a malignant primary brain tumor affecting about new cases per year in the U S Average survival is only about months Radiation RT is most commonly administered as fractions of Gray each over weeks with concomitant temozolomide TMZ GBM tumors are hypoxic The primary mechanism of RT is creation of singlet oxygen hypoxia within GBM adversel ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
SYSTEMIC RADIONUCLIDE THERAPY TARGETED TO VEGF RECEPTORS IN TUMOR VASCULATURE
SBC: SIBTECH, INC. Topic: NCIThe overall goal of this collaborative project between SibTech Inc PI Backer J and Johns Hopkins University PI Pomper M is clinical development of efficient and cost effective anti angiogenic Lu radiopharmaceutical scV Lu for VEGF receptor mediated targeting of angiogenic tumor vasculature Current very expensive anti angiogenic compounds induce transient regression of tumor vascula ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
IGF OT IGF BASE AWARD STANDARDIZED RECHARGEABLE ELECTRONIC NICOTINE DELIVERY SYSTEM POP MARCH THROUGH NOVEMBER N DA EXTEND THE PERIOD OF PERFORMANCE FOR NO ADDITIONAL
SBC: NJOY Inc. Topic: NIDANot Available
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
IGF OT IGF Topic Phase I SBIR Predictive Biomarkers of Adverse Reactions to Prostate Cancer Radiotherapy
SBC: L2 DIAGNOSTICS, LLC Topic: NCINot Available
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
IGF OT IGF Circulating nucleic acid based nanowell label free array technology in cancer
SBC: DETROIT R & D, INC. Topic: NCINot Available
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
IGF OT IGF Topic Phase I SBIR Defining normal tissue and tumor biomarkers of radiosenstivity to detect treatment
SBC: MIRA DX, Inc. Topic: NCINot Available
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Engineering a phosphotyrosyl-tRNA Synthetase
SBC: AXIOMX INC Topic: 300DESCRIPTION provided by applicant Although tyrosine phosphorylation is an important controlling element in cell signaling no tRNA suppressor for phosphotyrosine pTyr incorporation has yet been made We propose to use directed molecular evolution of several aminoacyl tRNA synthetases aaRSs to identify mutations that enable binding of pTyr to the aaRS Specifically ATP molecules will be att ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Rapid Monitoring and Assessment of Tubercuolosis Treatment at the Point of Care Using Breath
SBC: NanoSynth Materials and Sensors Inc. Topic: NHLBIDESCRIPTION provided by applicant Problem and Significance According to the CDC global statistics nearly of the world is infected with Tuberculosis TB In million f peopled infected lived in what is considered a high burden country Countries such as India Peru China sub Saharan Africa and others have significant regions endemic for TB particularly among the lower income ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
TruEnamel: A dental product that treats, protects, desensitizes and whitens teeth
SBC: TruEnamel, LLC Topic: NIDCRDESCRIPTION provided by applicant Dentin hypersensitivity is a painful condition affecting from of the population It is caused by the movement of fluid in the dentinal tubules and can be eliminated by occluding these patent tubules Tooth whitening is a $ billion business in America and is predicted to grow both here and abroad In this grant we propose a treatment for dentin hypers ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health