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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. High throughput Electrophysiological Purification Array HEPA for cell based therapies

    SBC: BIOPICO SYSTEMS Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant High throughput Electrophysiological Purification Array HEPA for cell based therapies Abstract Patient specific reprogrammed somatic cells induced pluripotent stem cells or iPSCs have raised hope for revolutionary regenerative treatments for heart lung and blood diseases and drug development applications For example these iPS cells can be differentiated ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Development of OCT Imaging Adapter for Interstitial Tissue Imaging

    SBC: WEST FACE MEDICAL DEVICES, INC.            Topic: NIBIB

    DESCRIPTION provided by applicant This Phase I STTR Grant Proposal requests $ support for WestFace Medical Device to construct and test the WestFace Imaging Adaptor in conjunction with Ruikang K Wang PhD and his laboratory at the University of Washington Utilizing optical coherence tomography OCT the patented OCT Adaptor USPTO Pats provides r ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Cell Lysates to Sequencing Reads: A Multiplex Gene Expression Profiling Tool for

    SBC: BioSpyder Technologies, Inc.            Topic: 172

    DESCRIPTION provided by applicant This proposed Phase I SBIR project will transfer RASL Seq a targeted sequencing technology developed in academia to a small business Xpress Inc and demonstrate feasibility for its commercialization as a platform for drug discovery and high throughput screening HTS The technology detects hundreds of RNA targets at once in cell lysates using oligo li ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Therapeutic Antibodies for CMV

    SBC: Trellis Bioscience, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Human cytomegalovirus HCMV is the major viral cause of birth defects and of medical complications associated with organ transplantation Passive immunization using human immune globulin HIG has been shown to prevent disease As pooled plasma however HIG is a variable product that potentially contains infectious agents or may cause side effects Native human monoclona ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Therapeutic D-peptide Inhibitor of HIV Entry

    SBC: NAVIGEN, INC.            Topic: NIAID

    DESCRIPTION provided by applicant With million people living with HIV AIDS including million in the US and million AIDS related deaths annually HIV AIDS remains a formidable global epidemic UNAIDS CDC Modern HIV therapy combines drugs from different classes to form andquot cocktailandquot therapies that have significantly prolonged the lives of many HIV patients However side effects and drug resis ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. A Human Fc Bifunctional Fusion Protein to Treat Severe Allergic Asthma

    SBC: TUNITAS THERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The overall goal of this phase SBIR proposal is to position our novel biologic GE for human clinical trials in allergic disease though the completion of critical preclinical development research activities GE a genetically engineered human fusion protein consisting of portions of the human gamma Fc linked to portions of the human epsilon Fc chain has unique mechan ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Magnetic Resonance Imaging Subsystem for Cardiac Ischemia Evaluation

    SBC: HeartVista, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Cardiac magnetic resonance imaging MRI has been shown to be one of the best technologies for the evaluation of cardiovascular pathologies The broad application of this promising technology is expected to significantly improve the treatment of patients with heart disease in general and ischemic heart diseases in particular However widespread adoption of th ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Safety of Allogeneic Cardiosphere-Derived Cells for Dilated Cardiomyopathy

    SBC: CAPRICOR, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant Project Abstract Capricor Inc has an allogeneic cell therapy product CAP presently in clinical development CAP consists of cardiosphere derived cells CDCs grown from a donor unrelated to the recipient using a proprietary process exclusively licensed to Capricor Autologous CDCs have demonstrated their utility as a regenerative agent able to ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Cloud-Based Bioinformatics for Immune Repertoire Analysis

    SBC: Gigagen, Inc.            Topic: NHGRI

    DESCRIPTION provided by applicant The Specific Aim of this Phase II SBIR grant application is to launch ClonoByteandquot a website and cloud based platform for the processing storage analysis comparison and visualization of immune signature data sets generated by deep sequencing of immune repertoires There is a rapidly growing demand for T cell receptor TCR and immunoglobulin Ig repertoire sequenc ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Non-invasive Blood Alcohol Sensor for Emergency Room Applications

    SBC: Epicentre Technologies Corporation            Topic: 150

    DESCRIPTION provided by applicant Project Summary Accurate quantification of alcohol and drugs of abuse intoxication in emergency rooms ERs is an important screening step for a precise diagnosis and hence for prompt treatment Some severe emergencies such as traumatic head injury diabetes and stroke can be misdiagnosed in the absence of screening for alcohol and drug intoxication reliable ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health

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