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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A circular array desktop ultrasound tomography system for cross sectional imaging of small animals
SBC: Sonamed Technologies, LLC Topic: 100The long term goal of the proposed project is the development of a desktop circular array Small Animal Ultrasound Tomography System SAUTS to produce high resolution cross sectional diagnostic images of mice and other small laboratory animals The SAUTS images will look familiar to the radiologist resembling those produced by Micro CT or MRI They will be easy to interpret as the circular tomog ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A fluorescent reporter detecting precise homologous recombination transgenesis activity
SBC: KDT, LLC Topic: NICHDThe broadlong term objective and specific aims of the fast track SBIR research are to create areagentRecombiREDfor use in microinjection of embryos for identifying a subset of embryosas recombination competent injectionsThe ability to quickly identify genome editing events inan embryo allows researcher to quickly make precision animal models of human disease statesPrecise animal models allow for g ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
Amyloid Beta Oligomer Induction of Alzheimer's Disease in Nonhuman Primates
SBC: Virscio Inc Topic: 100PROJECT SUMMARY Patients with Alzheimerandapos s diseaseADsuffer a progressive loss of memory and cognitive abilityand eventual loss of basic bodily functions and deathCurrentlyof Americans overhave AD and its incidence and toll on the healthcare system continues to rise with significant societal impactThere are no treatments for AD to prevent its inexorable courseand a principal obstacle to devel ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A nanoparticle delivery system for CRISPR Cas based therapeutics
SBC: ATGC Inc. Topic: NCATSAbstract Applications of customizable nucleases such as CRISPR clustered regularly interspaced short palindromic repeats Cas CRISPR associated protein have enabled efficient and precise gene correction in vitro and hold promises for eventually achieving in vivo gene correction therapy However to apply CRISPR Cas in therapeutic settings several major challenges remain to be addressed ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A New Co Expressed P and UGT Platform for the Simultaneous Preparation of P Metabolites and Their Glucuronides
SBC: OXFORD BIOMEDICAL RESEARCH, INC. Topic: 300Toxins pharmaceuticals and physiologically indogenous compounds are metabolized by the liver via several classes of enzymes The uridine diphosphate glucuronosyltransferases UGTs are concentrated in the liver but also present in other tissues These enzymes add UDP glucuronic acid UDPGA to a compound thereby increasing its solubility and ability to be excreted in the bile and urine Oxford B ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
An Integrated Microarray Printing and Detection System
SBC: BIOSENSING INSTRUMENT INC Topic: 400DESCRIPTIONprovided by applicantMicroarray technology has dramatically advanced the study of protein interactions leading to discovery and validation of new biomarkers and therapeutic drugsTypicallyprotein microarrays are pre spotted with target molecules in one device and then tested with probe molecules using another deviceDuring each testing cyclethe entire microarray becomes exposed to the pro ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
A novel approach to treat non alcoholic steatohepatitis NASH
SBC: MITOTHERAPEUTIX, LLC Topic: 300Abstract The Specific Aim of this Phase I STTR proposal is to test the feasibility of treating non alcohol steatohepatitis NASH by increasing mitochondrial metabolism which is the main pathway for lipid catabolism in the liver NASH is a stage of non alcohol fatty liver disease NAFLD that has progressed to a pathological state NASH can lead to cirrhosis leading to liver failure or hepatocel ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A Platform for Safe Noninvasive Prenatal Genetic Testing at Five Weeks of Pregnancy
SBC: Cradle Genomics, Inc. Topic: NICHDSUMMARY The overall goal of this research is to provide a flexible prenatal genetic testing kit that can be expanded to detect any inheritable trait as early as and up to weeks of gestation from a safe noninvasive Pap smear Studies show that perinatal Pap tests pose no risk to mother or fetus and capture trophoblast like cells that migrate from the placenta into the reproduct ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Application of PPODA QT for embolization of aneurysms
SBC: ANEUVAS TECHNOLOGIES INC Topic: 101A cerebral aneurysm is an abnormal enlargement or pouch that forms from a weakened vessel segment in the brain Often going unnoticed and untreated an aneurysm can cause a sudden and catastrophic hemorrhage or stroke Approximately of patients die from an aneurysm rupture even before receiving medical attention and of patients die despite medical treatment Patients that survive typical ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A Rapid Low Cost Point of Care Diagnostic for detection of Zika virus RNA
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDABSTRACT Zika virus ZIKV has rapidly emerged and spread through South and Central America the Caribbean and Puerto Rico since its last outbreak in Micronesia in Transmitted by the mosquito Aedes sp its forecasted spread will have a major impact on the Southeast U S Most ZIKV infections remain asymptomatic or present with non specific rash and fever therefore they have been difficult ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health