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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. HQ-55 VTOL UAS for Ship Based Operation

    SBC: Latitude Engineering, LLC            Topic: 832

    TECHNICAL ABSTRACT: The Hybrid Quadrotor concept, developed by Latitude Engineering, combines the high power density of electric motors and propellers with the high energy density of a piston engine and liquid fuel. Together, each technology enables maximum performance in HQ's two regimes of flight: the electric system is responsible for lift while hovering (high power, short endurance), and the g ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  2. Randomized Prospective Phase II Clinical Trial of NVX in Association with Chemoradiation of Glioblastoma

    SBC: NUVOX PHARMA, L.L.C.            Topic: 102

    Glioblastoma multiforme GBM is a malignant primary brain tumor affecting about new cases per year in the U S Average survival is only about months Radiation RT is most commonly administered as fractions of Gray each over weeks with concomitant temozolomide TMZ GBM tumors are hypoxic The primary mechanism of RT is creation of singlet oxygen hypoxia within GBM adversel ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Development of New Improved Perflutren Ultrasound Contrast Agent

    SBC: MICROVASCULAR THERAPEUTICS LLC            Topic: NHLBI

    Three ultrasound contrast agents Definity Optison and Lumason are FDA approved for echocardiography in the U S Definity currently has over market share Definity s dominance in the market is due to its ease of administration via IV infusion and robust ultrasound contrast Definity has shelf life of years and must be stored under refrigerated conditions Definity has an unpleasant ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A fluorescent reporter detecting precise homologous recombination transgenesis activity

    SBC: KDT, LLC            Topic: NICHD

    The broad long term objective and specific aims of the fast track SBIR research are to create a reagent RecombiRED for use in microinjection of embryos for identifying a subset of embryos as recombination competent injections The ability to quickly identify genome editing events in an embryo allows researcher to quickly make precision animal models of human disease states Precise animal m ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. VIRTUAL REALITY FOR MOBILE PAIN CONTROL

    SBC: MEDIA REZ LLC            Topic: NIDA

    Under this Small Business Innovation Research SBIR Phase II project Topic the Contractor will produce anditeratively test a virtual reality VR intervention with diverse populations of patients with chronic pain The Contractorwill develop and refine VR content based on patient and clinician feedback develop and implement a plan forusing the VR content as a therapeutic tool in a ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. PREDICTIVE BIOMARKERS OF ADVERSE REACTIONS TO PROSTRATE CANCER RADIOTHERAPY

    SBC: L2 DIAGNOSTICS, LLC            Topic: NCI

    The overall objective of this project is to advance the development of a clinically usefully multiplex assay todetect biomarkers of radio sensitivity that will identify subsets of prostate cancer patients for whichradiotherapy should be contraindicated This assay will be capable of predicting the risk of developingadverse effects principally urinary morbidity and rectal injury resulting from ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. High Stability Atmospheric Carbon Dioxide and Methane Analyzer

    SBC: LI-COR, Inc.            Topic: 832D

    LI-COR proposes to continue development of a next-generation CO2/CH4/H2O analyzer that will offer an unprecedented combination of high precision and stability, making it the first highperformance gas analyzer suitable for long-term unattended operation. The instrument will be smaller, lighter, and far less expensive than competing technologies. LI-COR’s approach exploits a proprietary, revolutio ...

    SBIR Phase II 2017 Department of CommerceNational Oceanic and Atmospheric Administration
  8. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Improving vaccine development through high throughput immunogenicity screening

    SBC: Carterra, Inc.            Topic: NIAID

    Abstract Vaccines are fundamental in preventing debilitating illnesses and saving millions of lives each year But despite these vaccine oriented victories infectious diseases are still the second leading cause of death as well as the leading cause of disability adjusted life years worldwide About six million deaths were attributed to AIDS malaria and tuberculosis in regions where no vaccine ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Novel Androgen Receptor Degraders to Treat Castration Resistant Prostate Cancer

    SBC: Arvinas, Inc            Topic: 102

    DESCRIPTION provided by applicant The overall aim of this grant is to generate data to understand and enable the development of a novel therapeutic approach for the treatment of patients with castration resistant prostate cancer Prostate cancer is the third most lethal cancer in the US with new cases and deaths projected to occur in While early detection surgery and horm ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health

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