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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Affordable Wastewater Disposal for Coastal Households Adapting to Sea Level Rise

    SBC: WAIHOME LLC            Topic: 92

    "Rising sea levels and king tide flooding in coastal areas across America are saturating onsite wastewater disposal systems (OSDS), resulting in the degradation of coastal ecosystems and 200,000+ illnesses annually. Many States are mandating system upgrades, with 88,000 upgrades required by 2050 in Hawaii alone. Unfortunately, existing upgrade options are unaffordable for 97% of Hawaiian homeowner ...

    SBIR Phase I 2023 Department of CommerceNational Oceanic and Atmospheric Administration
  2. Expansion and validation of novel mobile app for guiding home modifications for aging in place

    SBC: HomesRenewed Ventures LLC            Topic: R

    PROJECT SUMMARY In this Phase II SBIR, HomesRenewed Ventures, LLC (HRV Washington, DC) will build on our previous efforts to expand and validate an interactive mobile application (APP) for guiding home modifications (environmental interventions) critical to Aging in Place (AiP). Home modifications (HM) are associated with falls preventions, improved activities of daily living (ADLs), and emotional ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Noregen, a regenerative medicine ocular therapeutic

    SBC: Retinal Solutions LLC            Topic: NEI

    ABSTRACT Ischemic retinopathies, such as diabetic retinopathy and retinal vein occlusion, are the leading cause of blindness in the United States. Common features are leaky vessels, swelling, capillary drop out, aberrant vessel growth and retinal detachment. Current treatments include laser ablation, anti-VEGFs and steroids. All are sub-optimal and only serve to slow disease progression and vision ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. T-cell receptor mimic affinity reagent generation using an in vivo novel immunogen strategy

    SBC: ABBRATECH INC.            Topic: 300

    ABSTRACT Current therapeutic antibodies target the cell surface and within the external cellular environment. Yet intracellular proteins make up half of the proteome. Having a facile means of targeting those intracellular proteins for the generation of therapeutic antibodies would be highly desirable. Targeting MHC complexed with neoantigens from intracellular proteins would greatly allow the gene ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Development of an empathetic chatbot to monitor perinatal mental health longitudinally

    SBC: Poisera, Inc.            Topic: 104

    1 ABSTRACT2 One in five pre- or postnatal women will develop a perinatal mood disorder (PMD). While temporary and3 treatable, 50-65% of mothers with PMD symptoms never receive a diagnosis or treatment due to inadequate4 screening practices. PMDs remain undetected because mothers do not trust clinicians due to fear of judgment,5 stigma, or even loss of parental rights. Untreated PMDs increase risk ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Augmented Reality Personalized Motion Tracking Assessment and Improvement Technology for Fall Prevention for the Spanish Speaking Hispanic/Latino Population in a Community Setting Using Mobile Phone

    SBC: KINIMA, INC.            Topic: NIA

    More than 1 in 4 people 65 and older fall each year, leading to more than $50 billion in annual spending for treatment. This cost is on an upward trajectory. We have less understanding of the impact of falls and risk in the Spanish-speaking Hispanic/Latino population. Although a variety of community-based public health programs are addressing fall prevention, these programs are in English and are ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Dodecafluoropentane emulsion (DDFPe), NanO2™ as Cerebroprotectant in Ischemic Stroke

    SBC: NUVOX PHARMA, L.L.C.            Topic: NINDS

    ABSTRACT / PROJECT SUMMARY Stroke affects more than 795,000 patients per year in the US and kills approximately 40,000. Long-term medical care expense for stroke in the US, costs over $34B per year. Large vessel occlusion (LVO) stroke accounts for almost 40% of ischemic strokes but causes 95% of mortality and 62% of long-term dependence. Mechanical thrombectomy (MT), or a combination of MT and tPA ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Platform for the High Throughput Generation and Validation of Affinity Reagents

    SBC: ABBRATECH INC.            Topic: 300

    ABSTRACT We present a complete platform for the rapid generation and validation of recombinant mAbs. The innovations of this proposal include: (1) the pATHENA vector system for overnight conversion of phage display scFv or Fab clones into IgG molecules, (2) the Epivolve method for the isolation of site-specific Abs, (3) the incorporation of yeast display into pATHENA to allow biophysical measureme ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Topical Eyedrops Increasing Lysyl Oxidase Activity to Control Myopia

    SBC: Iveena Delivery Systems, Inc.            Topic: NEI

    Project Summary Pediatric myopia, also known as nearsightedness, is an eye condition in which one is unable to bring distant objects into proper focus. It is the leading cause of vision impairment in the world. The estimated economic impact of uncorrected refractive error is estimated to be a loss of $202 billion of global gross domestic product. The prevalence of myopia and high myopia are increa ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Stabilization of therapeutic microbes for inclusion in a liquid matrix for delivery to the intestines

    SBC: Vitakey Inc.            Topic: 300

    Project Summary/Abstract Enteral feeding (EF) is an essential medical procedure used to supply nutrients directly to the gastrointestinal (GI) tract of patients who are unable to eat independently. EF formula is often purchased as a ready-to-use liquid that contains carbohydrates, protein, fats, and micronutrients to ensure adequate nutritional benefit for the patient. The addition of therapeutic ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
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